Nonspecific immunostimulants. Immunomodulators list of drugs, use in treatment

Immunostimulating agents are designed to regulate the body's defenses. Due to a number of diseases, the human immune system does not work properly and does not perform all its functions.

These drugs were invented to help the body’s immune system self-heal. Many of the immunomodulatory drugs have an antiviral effect, and most often they are prescribed when a person suffers from ARVI several times a year.

It should be noted that medical practitioners treat immunomodulators differently. Some see good use in them, while others consider their use useless. You can also find different opinions among patients. To evaluate these drugs, let's look at the most popular immunomodulatory drugs today.

Effective immunomodulatory agents

Lycopid

The drug is used in complex treatment regimens for patients. The main indications for its use are: viral hepatitis, herpes, various secondary immunodeficiencies, purulent-inflammatory processes, tuberculosis, psoriasis and others.

The medicine has a powerful effect, therefore it is indicated for both treatment and prevention. Lykopid has cytotoxic activity, exhibits bactericidal properties, and promotes the resorption of small tumors.

1. The drug is available in tablets. The course of treatment depends on the severity of the disease.
2. In pediatric practice, lykopid is recommended for use from the age of three. In some cases, under the supervision of a doctor, the drug can be used for a child starting from one year of age.
3. In pediatrics, only one dose is allowed - 1 mg per day. For adults, the dose of the drug can vary, reaching up to 20 mg per day.

Pregnancy and lactation are contraindications for use.

The price for Lykopid (1 mg tablets No. 10) is around 230 rubles. For a dosage of 10 mg No. 10 you will have to fork out more; the cost for such a lycopid will be about 1,700 rubles.

Immunal

Immunal contains echinacea. The plant has antiviral, antibacterial, regenerating and anti-inflammatory effects.

Immunal is prescribed for influenza, ARVI, herpes, gynecological problems, and secondary immunodeficiencies. In minimal doses it is used to maintain normal immune function.

Contraindications to the use of Immunal are:

• tubinfection,
• rheumatoid arthritis,
• leukemia,
• allergic reactions,
• various systemic pathologies.

During pregnancy and lactation, the drug is acceptable in extreme cases.

Immunal is produced in tablets, drops, powder, and solution. The doctor selects the necessary form for treatment or prevention.

The price for Immunal (Slovenia) in tablets (No. 20) is 300-350 rubles.

Drops are offered for the youngest patients (from 12 months). Tablets are recommended no earlier than 4 years of age. Some pediatricians believe that it is preferable to use immunostimulating drugs in tablets only after 12 years. Dosing of the drug is carried out according to the instructions.

Kagocel

The drug has antiviral and immunomodulatory effects. Kagocel is similar in action to interferon. It is used to treat ARVI and herpes. Recommended for use from the age of three. The plus of Kagocel is the minimal possible side effects (individual intolerance and allergic reactions).

Depending on age and disease, the dose of the drug varies.

Kagocel (Russia) is available in tablets. The price per package (No. 10) is an average of 260 rubles. A course of treatment usually requires 10-18 tablets. Treatment of herpes will cost more, approximately 780 rubles.

Viferon

This drug acts comprehensively. The active substance is human recombinant interferon alpha-2. The product has the following properties: immunomodulatory, protective, antiviral, antiproliferative.

The range of applications for Viferon is quite diverse. These are ARVI, viral lesions of mucous and skin surfaces, stenosing laryngotracheobronchitis (in complex therapy), herpes, viral hepatitis, HIV, bronchial asthma, and others.

Viferon has also found widespread use in pediatrics. It is used even in newborns and premature babies.

Depending on the form of the drug, the dose of Viferon has its own characteristics. For example, suppositories are used 1-2 times a day, and gel up to 5 times a day.

The price for Viferon is as follows:

• gel 36000IU/ml 10ml costs about 180 rubles;
• suppositories 1000000IU (No. 10) - 520 rubles;
• ointment 40000IU/g 12g - 180 rubles.

In principle, Viferon can be classified as an inexpensive drug, which makes it popular among patients.

Amiksin

This drug, like many drugs with antiviral and immunomodulatory properties, is an inducer of interferon synthesis. It is used for liver diseases, acute respiratory viral infections, tubinfection and other diseases. It has been noted that amiksin is useful for urological, gynecological and neuroinfections.

The dosage of the drug is determined only by the doctor, because amixin is prescribed differently depending on the day of therapy.

Amiksin has few side effects: allergic reactions, chills, diarrhea.

In pediatrics, the drug is used only from the age of seven. The drug is not prescribed to pregnant women and persons with individual intolerance to the composition of amixin.

Tablets of 60 or 125 mg are available. The price of tablets (60 mg, No. 10) is 550 rubles.

Cycloferon

The drug is an inducer of endogenous interferon. Exhibits antiviral, immunomodulatory, antitumor, anti-inflammatory effects. Cycloferon reduces the content of carcinogens in the blood and also helps slow down metastatic processes in malignant neoplasms.

The effectiveness of cycloferon has been proven for hepatitis, HIV, ARVI, herpes, enteroviruses, chlamydia, tick-borne encephalitis and other infections. In systemic diseases, cycloferon exhibits moderate analgesic and anti-inflammatory effects.

The method of application depends on the severity of the infectious process (the instructions for use should be followed).

Contraindications: individual intolerance, allergies, pregnancy, lactation and liver cirrhosis. In pediatrics, the drug is used from 4 years of age.

Cycloferon is available in tablets, liniment and solution for injection. The price, respectively, is 190 rubles (10 tablets), liniment - 105 rubles, ampoules (5 pieces) - 330 rubles.

Thymogen

The drug belongs to the drugs that correct and stimulate the immune system.

The basis of thymogen is glutamine tryptophan. Immunodeficiency states are indications for prescribing this drug. No special contraindications or side effects were found.

Thymogen has three dosage forms: aerosol, injection solution, cream for external use.

The price of the drug depends on the dosage form. Injection solution 0.01% 1 ml No. 5 costs about 330 rubles. The price of cream for external use 0.05% 30g ranges from 270 to 330 rubles. Aerosol 0.025% 10 ml costs about 310 rubles.

Derinat

This drug has established itself as a powerful immunomodulator. The range of its applications is huge. These are oncological processes, chronic gastrointestinal diseases, cardiac pathologies, tubinfection, gynecological and urological infections.

Derinat activates all parts of the immune system and also stimulates regenerative processes. Thanks to derinat, tissue regeneration occurs faster, so this product is prescribed for the treatment of burns and ulcerative processes on the skin.

Dystrophic problems in eye diseases are eliminated faster when taking Derinat.

A big advantage of this remedy is the possibility of its use from the first days of a child’s life, when many medications are contraindicated.

Derinat is available in solution for injection or solution for local and external use.

The course of treatment depends on the disease and can range from 5 to 45 days. In any case, derinat treatment is not carried out independently.

A solution of 0.25% 10 ml for topical use costs about 300 rubles, a solution for injection 1.5% 5 ml No. 5 - 2000 rubles.

Anaferon

The effectiveness of anaferon has been observed in acute respiratory viral infections, bronchopulmonary pathologies, herpes infections, as well as other diseases caused by viral agents. Anaferon is a safe homeopathic drug with high antiviral protection. Bacteria, like viruses, also lose their strength thanks to the “work” of anaferon. Diseases with chronic immunodeficiency are a direct indication for this drug.

Like other immunomodulators, anaferon should not be used during gestation, but if particularly necessary, it can be used in the second and third trimester of pregnancy. This is due to the fact that after the 12th week of pregnancy the fetus is already more protected. The embryonic period passed, the placenta became thicker, and the unborn baby began to gain more body weight.

In pediatrics, anaferon is used once a day. As a rule, the course of treatment lasts a week. The pharmacy chain sells Anaferon for children (in drops and tablets). The form of the drug for therapy is selected by the doctor.

The price for children's and adult anaferon in lozenges (20 pieces) is about 200 rubles, in drops (25 ml) a little more expensive - 250-300 rubles.

Cheap analogues of Anaferon - list.

Lysobacter

The drug is popular in otolaryngology and dentistry. It is based on two active components - lysozyme and vitamin B6. The first fights infection, the second protects the mucous membrane. Despite the fact that lysobact is an antiseptic, its effectiveness in the fight against viruses has been proven more than once. The immunomodulatory effect of lysobact is weak, so it can be safely used during gestation and lactation.

Lysobact is prescribed for infections and inflammation of the pharyngeal space, stomatitis, gingivitis, aphthous ulcerations, and herpes.

Side effects while taking lyzobact appear extremely rarely. Only mild allergic reactions are possible.

The course of treatment lasts about 8 days. The tablets are dissolved slowly under the tongue (sublingually). It is advisable to keep the dissolved mass under the tongue for as long as possible and refrain from eating food and water for several hours.

Tablets are used from 3 to 8 pieces per day. Children from 3 to 7 years old are recommended to take 1 tablet three times. For adults, the following dosage is recommended - 2 tablets 4 times a day.

The price of lysobact (Bosnia and Herzegovina) No. 10 is 250-320 rubles.

Remantadine

Conclusion

Analyzing our article, it is easy to notice that many drugs have much in common. This is especially true for indications for use. To date, there is still a lot of controversy regarding the use of immunomodulators. There are opinions that the body itself is capable of recovering, and immunomodulators act only as a placebo.

Immunostimulants It is customary to call those substances that stimulate the body’s nonspecific resistance and person. Very often the terms " immunostimulant " And " immunomodulator " are used as synonyms. However, there is still a certain difference between such drugs.

Types of drugs that affect the immune system

All drugs that in one way or another affect the immune system are usually divided into four types: immunocorrectors , immunomodulators , immunostimulants , immunosuppressants . Application immunomodulators It is advisable in the case of treatment of malfunctions in the immune system, as well as to restore the functions of this system. Such drugs are used for treatment only after prescription by a specialist.

Preparations- immunocorrectors act only on some parts of the immune system, but not on its work as a whole. Facilities- immunosuppressants , on the contrary, do not stimulate, but suppress its work if its functioning is too active and harms the human body.

Preparations- immunostimulants are not intended for therapy: they only strengthen the human immune system. Under the influence of these drugs, the immune system functions more efficiently.

Immunomodulators have different origins and affect the human immune system depending on its initial state. Experts classify such agents according to their origin, as well as based on the mechanism of their action. If we consider the origin of immunomodulators, they are divided into endogenous , exogenous And chemically clean drugs. The mechanism of action of such drugs is based on the effect on T- , B-system immunity , and phagocytosis .

How do immunomodulators and immunostimulants work?

The human immune system is a unique body system that can neutralize foreign substances entering the body. antigens . Immunity prevents the harmful effects of pathogens of infectious diseases. Immunomodulators are capable of influencing changes in human immunity.

Immunostimulants act specifically on the functioning of a specific part of the immune system, activating it. And immunomodulators are prescribed in order to balance all components of the immune system, while the activity of some increases and the activity of others decreases.

However, taking these drugs must be strictly dosed, since if the treatment is too long, the body’s own immunity may be less active. If immunostimulants are used for too long without proper supervision by the attending physician, such drugs can negatively affect the immunity of both the child and the adult patient.

Indications for the use of immunomodulators

The main indicator that is taken into account when prescribing immunomodulators is the presence of signs of immune deficiency. This condition is characterized by a very frequent manifestation viral , bacterial , fungal infections that are not affected by traditional methods of therapy.

Before starting treatment, the doctor must determine what kind of immune disorders a person has, as well as how severe these disorders are. If a healthy person is diagnosed with a decrease in a certain immunity parameter, then taking such drugs is not always advisable. In this case, it is important that the patient is examined and consulted by a specialist immunologist.

Often, in parallel with immunomodulators, patients are prescribed vitamin-containing drugs, as well as And microelements . In most cases, sorption therapy is prescribed as an additional method in order to reduce the level of endogenous intoxication.

Immunostimulants and immunomodulators of plant origin

In addition to artificially synthesized drugs, immunomodulators and immunostimulants of plant origin are also actively used. Such drugs naturally and gradually restore the body, without changing the hormonal balance. These preparations are created on the basis of medicinal plants: nettle, chicory, lungwort, yarrow, clover, etc. In addition to medicinal plants, some food plants also have immunostimulating properties

Has very powerful immunostimulant properties echinacea . This is a herbaceous perennial plant, the extract of which is very often used today both in cosmetics and in the manufacture of medicines. Echinacea promotes the formation of red blood cells, it enriches the body selenium , calcium , silicon , vitamins A , WITH , E and other elements no less important for life and strengthening the immune system. In addition, preparations based on Echinacea have antiallergic , diuretic , anti-inflammatory , antibacterial , antivirus influence. Mainly used is a ten percent alcohol tincture of Echinacea, as well as herbal preparations that include this plant. Quite popular preparations are also made based on echinacea. , Immunorm . These remedies have a gentle and beneficial effect on the human immune system. They are prescribed even to children who are already one year old. For preventive purposes, these drugs are recommended to be taken three times
per year, one month at a time, which helps strengthen the resistance of the human body as a whole.

Preparations based on echinacea are used as immunostimulants for children. However, it is very important to take into account that immunostimulants of plant origin cannot be used uncontrolled, since there are certain contraindications that need to be known before use.

In addition to echinacea, a popular natural immunostimulant is the extract Eleutherococcus roots . Adults take 30-40 drops of this plant infusion, and children should count one drop of infusion for one year of life. Today, Eleutherococcus extract is very often used as a means of preventing infection. And cold during the epidemic. Quite often in such cases they also use ginger . Immunomodulators for children are often used in kindergartens, and are also recommended for use at home during epidemics.

Use of immunostimulants for children

It is very important that immunostimulants and immunomodulators for children are used especially carefully. After all, a number of such drugs have clear contraindications, information about which is indicated in the instructions for these drugs. Treatment with such means should not be given to children whose relatives have been diagnosed with , since their exposure can provoke the development of such diseases in a child. Among the diseases that are indicated as contraindications, it should be noted insulin type , , multiple sclerosis , scleroderma , as well as other autoimmune diseases. Most of these diseases are incurable.

But there are also direct indications for the use of such drugs to treat children. Thus, immunostimulants for children are prescribed for some serious illnesses. This flu with complications , severe coldA . Immunomodulators are also used to treat pregnant women with colds, since such drugs have relatively few contraindications.

A very useful and practically harmless immunostimulant that is perfect for children is honey. It contains a very large number of useful essential vitamins And microelements Moreover, children consume such a tasty medicinal product with pleasure. Even small children who have not yet turned one year old can be treated with honey. The only contraindication in this case is allergic reactions for honey

In order for a child’s immune system to function at full strength, it is necessary to regularly replenish the supply of certain microelements. It is very important to constantly consume foods containing zinc: peas, carrots, oats, red bell peppers, buckwheat. Garlic is a very strong immunostimulant. However, it is important to note that children under three years of age can only be given boiled garlic.

But still, immunostimulant drugs, as well as drugs of this type that are of plant origin, are not ordinary vitamins. Therefore, if it is necessary to use this type of drug to strengthen the immunity of children, you should still consult with specialists.

Immunomodulators for the treatment of herpes

is a disease in the treatment of which some immunomodulators are also actively used. Drugs belonging to the group of interferons and used for the treatment of herpes are, . The drug amixin has a pronounced effect on viruses and stimulates the body's production of interferons.

Recurrent herpes infections are often treated with medications Viferon , Gyaferon , leukinferon , which contain recombined human interferons. These immunostimulants for herpes effectively support the body's antiviral resistance.

In addition, other drugs of this type are used for herpes. An immunomodulator drug stimulates the formation in the body and activates its antioxidant system.

For young children with herpetic immunodeficiencies, treatment with the drug Lykopid is indicated. The doctor prescribes a treatment regimen for this drug on an individual basis.

In addition, for herpes in children and adults, drugs are used as immunostimulants, Tamerite , epithelamin , and a number of other effective drugs.

After birth, the child has natural maternal immunity for some time, protecting the baby from diseases. But over time, the immune system weakens, and the child’s body independently learns to fight illnesses.

The group of immunostimulants appeared on the pharmaceutical market not so long ago and has already conquered its segment of buyers. The action of these drugs is aimed at strengthening, enhancing and stimulating children's immunity. These are synthetic and natural drugs, which at the initial stage of their appearance were recommended as antiviral agents.

But when observing young patients taking drugs to enhance immunity, it became clear that they can be used not only to treat illnesses of viral etiology, but also for immunodeficiency of other origins.

Due to the action of these funds, all organ systems begin to work more productively.

You cannot take immunostimulants on your own- this is very important for parents to learn, who, at the first appearance of a runny nose in a child, buy a long list of all kinds of medications at the pharmacy. There is a clear list of indications for use that must be strictly followed.

Carefully! Uncontrolled use of immunostimulants can lead to a decrease in the child’s own immunity, and the prescription of immunostimulants for children under 3 years of age is not recommended at all.

It is also worth noting that an immunostimulant is not a magic pill that will rid a child of the disease. Like all drugs, they have contraindications and side effects, so Only an immunologist should prescribe a particular drug taking into account the individual characteristics of the baby’s body. Otherwise, your health may not be strengthened, but undermined.

Taking immunostimulants also does not exempt parents from other ways to strengthen the immune system - vitaminization of the body, hardening, sports. Pills alone will have little effect on the immune system; a set of measures is needed that will complement each other. Only in this case will it be possible to talk about the formation of strong protective forces in the child’s body.

Indications for use

Usually, before prescribing immunostimulants, the doctor prescribes a series of tests that can be used to determine degree of decreased immunity. A carefully collected anamnesis allows you to determine the weakest system of the child’s body, which is most often affected. Based on these data and indications for the use of drugs, appropriate medications are prescribed.

The indications include the following:

• the presence of chronic recurrent diseases;
• taking drugs that weaken the immune system;
• sluggish infectious processes;
• severe viral and bacterial infections;
• the presence of diseases in which secondary immunity is stimulated;
• malignant tumors;
• congenital immunodeficiencies;
• metabolic disease;
• the need for recovery after chemotherapy, radiation therapy;
• immunodeficiencies caused by unfavorable external factors.

Any medications, even those to boost immunity, should not be taken without a specialist’s prescription

Only if these indications are identified, the doctor will select an immunostimulating drug for the child.

Types of immunostimulants

Today, there are several approaches to classifying drugs based on various characteristics, but it is most convenient to divide immunostimulants for children into two categories:

• vegetable (natural);
• synthesized by the pharmaceutical industry.

Laboratory synthesized immunostimulants

Laboratory drugs for enhancing immunity have already survived three generations - each time they become more and more effective and bring fewer side effects. Such drugs vary in form, direction of action and strength. As a rule, they are used in combination with other medications, complementing each other.

The list of immunostimulant drugs for children is wide; all drugs have their own characteristics and indications. Some of them:

• Amiksin- helps the baby get rid of frequent;
• Anaferon, Viferon- from respiratory tract infection;
• Dekaris- activates the immune system in the fight against the herpes virus;
• Bronchomunal- increases local immunity of the respiratory system (the baby will get sick less);
• Derinat- for protection against acute respiratory infections;
• Ronkoleikin- a universal remedy that strengthens the immune system for lesions of various etiologies.

Herbal immunostimulants

Nature has provided humans with a number of immunostimulants that act no less effectively than synthetically generated drugs. Immunostimulant plants have long been used in folk medicine, and today we can evaluate the experience of using this or that remedy.

As practice shows, effective natural analogues are cranberries, honey, garlic, onion and ginger. Extracts of these remedies are included in many preparations, but traditional medicine experts advise giving them to children according to special recipes.

No less powerful immunostimulants are echinacea, nettle, lemongrass, eleutherococcus, licorice, white iris. These products have a gentle effect on the body, almost do not cause allergic reactions, they can be used for quite a long time, since they have a cumulative effect and do not act immediately.

Important! Natural immunostimulants are not as effective as synthetic drugs, so if you need to quickly boost your immunity or if you have a serious illness, they cannot be used, so as not to provoke a worsening of the situation.

Medical opinion

Medical opinions about immunostimulants vary. Some doctors believe that prescribing immunostimulants is a good and almost the only way to boost immunity in children, and doctors often prescribe such drugs at the first treatment with cold symptoms.

Another, rather skeptical opinion regarding immunostimulants is held by the well-known pediatrician Evgeny Olegovich Komarovsky.

In his interviews he shows and ridicules the “deification” of immunostimulants, as magical remedies that restore children to health.

For this reason, the doctor even came up with sonorous names - Immunoukrepin, Kashleprekratin and Sopleischeznovin.

« Unfortunately, this irony is a reflection of our reality,” says the doctor. “Nowadays it’s easier for parents to give a pill of some kind of drug than to harden the child, forming a strong immune system from the cradle. And when the beneficial time has passed, the mother’s immunity has ceased to act, and her own has not yet formed, an endless series of colds, allergies and other ailments begins.»

According to the doctor, there is not a single drug that can improve a child’s weakened immunity one hundred percent. But if you still have to choose immunostimulants for children, Komarovsky recommends doing this only after a thorough examination and immunogram.

Harm and side effects

Prescribing immunostimulants is one of the last resorts when the child’s own strength cannot cope with the disease. Interfering with natural processes can do more harm than good, and the side effects of drugs will be no less negative than the root cause of the disease.

There is always a serious risk of complications among which the following can be noted:

• the appearance of allergic reactions that have not previously been observed;
• joint damage;
• disruption of the cardiovascular system;
• infectious-toxic shock;
• decreased immunity to certain types of pathogens (for example, when taking immunostimulants, children may develop thrush).

Usually, with the correct selection of immunostimulants and compliance with the dosage of drugs, such complications do not arise. Therefore, under no circumstances should you change the dose of the prescribed drug or increase the frequency of its administration.

Immunostimulants for children are not essential drugs as long as the child’s body can cope with the disease on its own. Each transfer is another step towards the formation of stable defenses of the body, and only in extreme cases does it need to be helped to fight diseases.

During seasonal temperature changes, many people think about strengthening the body's defenses. Some people strive to spend more time outdoors and eat healthy foods, while others prefer special immunomodulator drugs without understanding their action. Drug treatment should be used as directed. can cause considerable harm to the body.

What are they?

Medicines that affect the functioning of the immune system are called immunomodulators. All medications in this series can be divided into two groups. Some of them stimulate immune reactions, thus increasing the body's protective functions. But medicine also uses drugs that suppress the immune system. Under no circumstances should immunomodulators be used independently. Such drugs are prescribed only by a doctor.

Immunomodulators can restore the body's defenses in various diseases. Most often they are prescribed for the treatment of viral and bacterial infections in a hospital setting. This allows the body to quickly get into shape after illness. For prevention purposes, doctors never prescribe immunomodulators. Drugs from this series are not beneficial for a healthy body.

Who are immunomodulators really indicated for?

Strong drugs that stimulate the immune system are prescribed to people with serious health problems. There are a number of diseases in which the body cannot cope with simple infections on its own. This is primarily HIV. In order for a person to feel normal and not be in danger at the slightest hypothermia, he needs to support his body with expensive medications.

Improper functioning of the immune system can also occur in babies who were born prematurely. In order for the child to be able to breathe independently and develop normally, he is prescribed immunomodulators. The list of drugs that can be prescribed to newborns is not too long. All medications in this series are quite expensive.

Stimulation of the immune system in children

Most often, parents are concerned about the health of their children when they start going to kindergarten. A child who previously was practically not sick begins to get an infection almost every month. This is absolutely normal. The baby enters a new environment with its own microflora and bacteria. Until the immune system is strengthened, the child will continue to get sick. This is called “adaptation to kindergarten.” It would be wrong to use immunomodulators during this period. Drugs of this type only suppress the normal development of the body's defenses. The child must cope with new microorganisms on his own.

A cause for concern may be the development of complications after another cold. If simple snot ends in purulent otitis, and a sore throat ends in sore throat, the doctor may advise taking immunomodulators. A list of medications is provided to each patient individually based on the form of the disease and the characteristics of the baby’s body.

Why do adults often vomit?

For an adult it should work at full capacity. It is no coincidence that those who feel chronic fatigue and begin to get sick often immediately run to the pharmacy and purchase immunomodulators. But first of all, it is worth understanding the reasons for this condition. It is advisable to visit a doctor. Often, poor health and pain are associated with the presence of old foci of infection in the body. This may be tonsillitis that is not cured in a timely manner or a banal carious cavity in the tooth.

Medicines should only be used when a person’s condition sharply worsens. Immunomodulators are often used together. The presence of malignant cells in the body indicates that the protective functions are not working well. Treatment in this case should be comprehensive. Expensive drugs are used that can restore immunity as quickly as possible. Below is a list of immunostimulating drugs that are found in domestic pharmacies.

"Wilosen"

The drug is made on the basis of the thymus gland. Contains amino acids, oligopeptides and inorganic salts. The drug perfectly strengthens the body's defenses and also suppresses the development of hypersensitivity. The drug "Vilozen" is used topically. In pharmacies, the drug is presented in the form of drops that can be instilled into the nose or added to a solution for inhalation. Most often, such immunomodulators and immunostimulants are prescribed for allergic reactions. Preparations like "Vilozen" cope perfectly with cough and swelling of the mucous membrane during the spring flowering period.

Vilozen drops are prescribed to adults and children over 12 years of age. They cannot be used in their pure form. If the drug is used for instillation into the nose, first add 2 ml of water or sodium chloride to the ampoule. During an exacerbation of the disease, 7 drops are instilled into each nasal passage 5 times a day. Additionally, intranasal inhalations can be performed. The course of treatment can be no more than 20 days. There are side effects from using the product, but it can only be canceled if there is an individual intolerance to individual components. In the first days of taking Vilozen drops, you may experience slight weakness and dizziness.

The drug is prescribed with caution to patients with bronchial asthma. Severe or the presence of acute bacterial infection is a contraindication to the use of Vilozen drops.

"Galium-Hel"

This drug belongs to the group of homeopathic drugs, so it can be used by children from an early age, as well as by women during pregnancy and lactation. The medication activates the action of the neutralizing functions of the body's cellular systems. Stimulation of the immune system occurs with minimal harm to health. The drug "Galium-Hel" is presented in pharmacies in the form of a solution. It is most often prescribed to people who have suffered severe infectious diseases. Chronic ailments that are accompanied by impaired enzyme metabolism are also an indication for the use of Galium-Hel drops. In addition, the medication perfectly stimulates the body’s protective functions in people over 70 years of age.

Even homeopathic immunomodulators (medicines) should not be used without consulting a doctor. It’s easy to guess why they are harmful to children and adults. Protective functions that are additionally supplemented with medications do not work to their full potential on their own. A healthy body can easily cope with an infection. Help is needed only in the most difficult cases.

The drug "Galium-Hel" can only be prescribed by a doctor. The dosage is determined depending on the form of the disease, as well as the individual characteristics of the patient’s body. Usually use 10 drops 3 times a day. During an exacerbation of the disease, you can take 10 drops every half hour. In this case, the daily dosage should not exceed 200 drops. For patients with a precancerous condition, it is advisable to use Galium-Hel drops in combination with other homeopathic medicines.

"Immunal"

The drug contains echinacea juice, which stimulates bone marrow hematopoiesis. As a result of taking Immunal, the number of leukocytes in the blood almost doubles. In addition, the drug has an antiviral effect. It is prescribed in combination with other medications for the treatment of herpes and respiratory diseases.

Immunomodulators are most often used for influenza purposes during seasonal temperature changes. Immunal is not prescribed to children under one year of age. During exacerbation of epidemics, the drug is taken once a day. For adults, 20 drops of solution are enough. For children, the dosage is determined by age. For children under 6 years old, 5-10 drops are enough. For colds, the drug "Immunal" can be taken up to three times a day. The course of treatment should not exceed 8 weeks. To preventively strengthen the immune system, it will be enough to take the drug for a week.

The “Immunal” product has virtually no side effects. In rare cases, hypersensitivity to certain elements of the drug occurs. During long-term storage, Immunal drops may become cloudy. There is no point in throwing them away. You just need to shake the bottle a few times and the contents will return to their previous state.

"Immunoglobulin"

The normal functioning of the protective function of the human body is impossible without special substances - immunoglobulins. But for a number of reasons, this substance stops being produced or is found in the body in large quantities. Medications can come to the rescue, one of which is called “Immunoglobulin”. Most often, the drug is used in replacement therapy as a prophylaxis for primary immunodeficiency syndromes. In addition, the drug can be prescribed when the body's defenses can no longer cope with a severe infection. This could be sepsis, severe bacterial diseases. The drug "Immunoglobulin" can be prescribed to pregnant women in case of Rh conflict with the fetus, as well as to premature infants in order to prevent severe infections.

Immunomodulators of this type are quite expensive. Medicines for children and adults are prescribed only when there is a serious threat to life and health. The cost of one ampoule of immunoglobulin is at least 1000 rubles.

The drug is administered intravenously through a dropper. The dosage is determined by the doctor depending on the form and severity of the disease. A single dose should not exceed 0.8 g/kg body weight. Most often, the medication is administered once and the procedure is repeated after a few weeks. Pregnant women with Rh-conflict are given Immunal after 32 weeks of pregnancy.

Side effects may occur only in the first few hours after taking the drug. This may include dizziness and nausea. The unpleasant sensations quickly pass. On the day of the IV drip, it is advisable for the patient to remain in bed and not plan any serious activities. The drug "Immunal" is contraindicated only in patients with individual intolerance.

"Leakadin"

A medication that is used as part of complex therapy for cancer in adults. In pharmacies, the product is presented in the form of a solution for injection. In case of cancer, immunomodulators must be used. Your doctor will tell you the names of drugs that can replace Leakadin. Medicines of this type not only have an immunostimulating effect, but also stop the growth of malignant tumors.

Before use, Leakadin is diluted with isotonic sodium chloride solution. The patient is given an injection once a day for two weeks. If necessary, the course is repeated after a month. Immunomodulators (drugs) have a number of side effects. Reviews show that Leakadin solution can cause a decrease in blood pressure, dizziness, and headache. In case of a sharp deterioration in health, the dosage of the drug is reduced. The doctor can completely cancel the drug only in case of individual intolerance.

Immunostimulants of natural origin

It is not always useful to use immunomodulators. The list of drugs is quite large. Moreover, all medications are intended to treat serious diseases. How then to strengthen the immune system during seasonal temperature changes? There are a huge number of products that stimulate the body's protective functions. First of all, these are fruits containing ascorbic acid. At the end of autumn, it is worth including citrus fruits in your diet. Just one slice of lemon in tea can perfectly strengthen the immune system.

If it is not possible to avoid a cold, fermented milk products and honey should be added to drug treatment. Interferon preparations and immunomodulators of natural origin are perfectly combined. Additionally, you can strengthen your immune system with echinacea tincture. You can buy it at the pharmacy.

Immunomodulators are now very popular - they improve the body’s protective function and are intended for adults and children. But these medications must be used wisely: improper use can cause serious harm to a person. In this article, the reader will learn how immunomodulators affect the body of adult women and men, including children. The text contains the characteristics of specific drugs and reviews of people who assessed their effects, which are freely available on various Internet sites.

What kind of immunomodulator medicine is this and what effect does it have?

A person can be congenital or acquired. The first type of defense is depleted very quickly and is not able to resist the pathogen for a long time. The acquired one is activated after the innate resources are exhausted; it has memory: in many cases, having once had an illness, a person tolerates re-infection more easily, because the acquired immunity has remembered an effective antibody to a given pathogen.

Attention! This principle is used in vaccination, when a weakened pathogenic microorganism is injected into a person, allowing the immune system to analyze the pathogen and develop effective protection.

When the body is unable to cope with the disease, immunomodulators are used. These are drugs that change the characteristics of the human immune system. There are 2 groups of immunomodulators:

• immunostimulants– force the defense system to act more actively;
• immunosuppressants has a depressing effect on the immune system, lowering it.

There is a difference between immunomodulators and immunostimulants: the former contain useful substances that help a person’s defenses overcome the disease, strengthen it, while stimulants artificially activate the immune system, forcing the use of internal reserves to fight.

The following groups of diseases can be distinguished for the treatment of which immunomodulators are used:

• chronic infections;
• allergy;
• tumors;
• immunodeficiency ().

Attention! Immunosuppressants are needed when the immune system malfunctions, causing it to act against its own body.

Reception and treatment with immunomodulators occurs when a doctor prescribes complex treatment, when the patient takes different groups of medications: antibiotics, antivirals and other drugs. This combination increases the body's defenses during active therapy.

These funds can also be used to speed up the patient’s rehabilitation period. After a course of administration, their effect continues for a long time, up to several years.

Classification of drugs, immunomodulators for children

These drugs, immunomodulators, are divided into 3 groups:

1. Endogenous– synthesis of substances occurs in the body itself.
2. Exogenous– all necessary substances and compounds come from outside with the intake of plant substances and beneficial bacteria.
3. Synthetic- completely artificial drugs.

We can distinguish herbal immunomodulators for adult women and men: many of them are used in traditional medicine recipes; since ancient times, people have discovered the healing properties of some plants. Among them, two groups can be distinguished:

• aggressive;
• soft.

The first group of plants has a more complex composition and is capable of inhibiting the defense system if used incorrectly. This group includes: licorice, yellow egg capsule, mistletoe and etc.

The second group is broader in composition; these plants help the immune system without side effects. This ginseng, Aralia, nettle, thyme, pine and nuts, garlic, figs etc.

Attention! The second group of medications can be recommended for self-medication (according to prescriptions), the first - only after consultation with a doctor and under his supervision.

It is necessary to give immunomodulators to a child very carefully, since the child’s defense system is at the stage of formation. Unreasonable use of immunomodulators and their active substances can lead to suppression of the child’s immunity.

Children over 6 years old are allowed to give immunomodulatory drugs no more than twice a year; children under 2 years old can use them only under the supervision of a doctor in difficult situations.

There are different points of view regarding the possibility of using various immunomodulators in children; for example, Dr. E. Komarovsky, a famous children's doctor, believes that children should not be given immunomodulators - this can lead to abnormal development and inability to protect themselves from the disease. Each parent is free to have their own point of view, but it is recommended to analyze all the pros and cons in advance.

You need to remember the main thing: the use of these medications, immunomodulators, immunostimulants or immunosuppressants, is possible only after consultation with a specialist. For both children and adults, it is possible to obtain a beneficial effect from taking immunomodulators only by selecting the right dose and taking into account the specific characteristics of a person’s health.

Improper use of immunomodulators can lead to a significant weakening of the immune system; in some situations, their use is contraindicated - for example, in the presence of autoimmune diseases, drugs can cause unpredictable and even fatal consequences.

The use of immunomodulators in the treatment of various diseases

1. . It is a viral disease, the causative agent of which is present in almost every person in a passive form. When comfortable conditions arise (the development of other diseases, weakening of protection), the virus begins to manifest itself as a pathogen, causing the development of the disease. Immunomodulators are used, among which the most effective are drugs from the group of interferons and certain nonspecific drugs (Cordyceps, natural immunity modulators, etc.). Treatment is most effective with simultaneous vitamin therapy.
2. Cold. Most often, the disease is of a viral nature and is associated with hypothermia. For treatment the following are used:

• antiviral immunomodulators as prescribed by a doctor;
• all natural remedies (as a complementary self-medication).

For colds, immunomodulators are used only in case of a complicated course of the disease, for example, if the high temperature persists for several days and the symptoms of acute respiratory infections do not subside. Only in this case will the attending physician prescribe an intensive course of therapy.

1. Flu. For the treatment of this disease, all natural, herbal immunomodulatory agents are indicated -, cranberry, rose hip, Melissa, . It is possible to use antiviral and anti-inflammatory immunomodulators (, etc.).

Attention! Herbal immunomodulators are allowed to be used only in the absence of contraindications (allergic reactions or concomitant diseases). It is recommended to consult a doctor before use.

1. Immunodeficiency virus (). This is a dangerous pathology that gradually deactivates the human defense system. Despite the fact that immunomodulators cannot eliminate this virus, the drugs can activate the immune system and significantly alleviate the patient’s condition. Medicines are used in conjunction with antiretroviruses and other drugs necessary for HIV-infected people. In addition to synthetic immunomodulators, natural drugs are widely used.

List of effective immunomodulators and reviews

The list of immunomodulators today is quite large and varied.

Interferon

Interferon is an antiviral and antitumor modulator that is synthesized in the body itself. Interferon is used as:

• prophylactic agent for ARVI epidemics. The sooner you start taking a drug from the interferon group, the better the body will resist the effects of pathogens;
• to restore the body, immune system, after serious illnesses.

It is in the ranking of the most effective drugs for strengthening the immune system. The most common form of interferon release is ampoules with powder, which must be diluted with water and dropped into the eyes and nose. Also available in the form of rectal suppositories and for intramuscular injections.

Reviews of the use of Interferon:

“Interferon” perfectly increases the body’s defenses, I can say this from my husband and I’s experience. I bought it as prescribed by a doctor in the form of a dry powder in ampoules. The important thing is that you should not dilute the medicine too much, because the medicine is stored in the refrigerator for only a couple of days. This is a very good antiviral immunomodulator, protects against influenza and ARVI. It is better to use only after consulting a doctor: there are contraindications.

Anastasia, 29 years old

Not everyone talks about this, but Interferon cannot be used constantly. Yes, he helped me quickly get my child back on his feet. Having seen such a miraculous effect, I instilled the drug in him every day, and when I stopped it in the spring, he immediately fell ill. It turns out that if you give the medicine for a long time, it will suppress the immune system, preventing the body from synthesizing its own interferon. So this medicine needs to be taken in moderation.

Ira, 35 years old

There are restrictions on the use of the immunomodulator Decaris for pregnant women, for example, when taken during lactation, breastfeeding is prohibited.

Children over 3 years old can use decaris in strictly dosed doses. The cost is about 75 rubles per pack with one Dekaris tablet.

Reviews of the use of Decaris tablets:

Kirill 34 years old

Anton, 33 years old

Lycopid

In the photo, Likopid tablets are a strong immunomodulator and immunostimulant for adults and children.

Lykopid is a powerful immunomodulator and immunostimulant. Likopid is effective in the treatment of purulent-septic infections. Due to its bactericidal activity, Lykopid can be used as an antitumor drug, and is also used during therapy:

• psoriasis and other skin diseases;
• eye infections;
• hepatitis (infectious).

Attention! Likopid is considered a very strong drug, so it must be taken in doses; it is contraindicated during pregnancy and breastfeeding.

Lykopid® - instructions for use

Release form, composition and packaging White, round, flat-cylindrical tablets, with a chamfer and a score. 1 tab. glucosaminylmuramyl dipeptide (GMDP) 10 mg Excipients: lactose monohydrate – 184.7 mg, sugar (sucrose) – 12.5 mg, potato starch – 40 mg, methylcellulose – 0.3 mg, stearate – 2.5 mg. 10 pieces. – blister contour packages (1) – cardboard packs. Pharmacological action Pharmacodynamics The active substance of Lykopid® tablets is glucosaminylmuramyl dipeptide (GMDP) - a synthetic analogue of the structural fragment of the membrane (peptidoglycan) of bacterial cells. GMDP is an activator of innate and acquired immunity, strengthens the body’s defense against viral, bacterial and fungal infections; has an adjuvant effect in the development of immunological reactions. The biological activity of the drug is realized through the binding of GMDP to the intracellular receptor protein NOD2, localized in the cytoplasm of phagocytes (neutrophils, macrophages, dendritic cells). The drug stimulates the functional (bactericidal, cytotoxic) activity of phagocytes, enhances their presentation of antigens, the proliferation of T- and B-lymphocytes, increases the synthesis of specific antibodies, and helps normalize the balance of Th1/Th2 lymphocytes towards the predominance of Th1. The pharmacological action is carried out by enhancing the production of key interleukins (interleukin-1, interleukin-6, interleukin-12), TNF alpha, interferon gamma, colony-stimulating factors. The drug increases the activity of natural killer cells. Likopid® has low toxicity (LD50 exceeds the therapeutic dose by 49,000 times or more). In the experiment, when administered orally in doses 100 times higher than the therapeutic dose, the drug does not have a toxic effect on the central nervous system and cardiovascular system, and does not cause pathological changes in internal organs. Likopid® does not have embryotoxic or teratogenic effects and does not cause chromosomal or gene mutations. Experimental studies conducted on animals provided data on the antitumor activity of the drug Lykopid® (GMDP). Pharmacokinetics The bioavailability of the drug when taken orally is 7-13%. The degree of binding to blood albumin is weak. The time to reach Cmax is 1.5 hours after administration. T1/2 – 4.29 hours. Does not form active metabolites, is excreted mainly through the kidneys unchanged. Indications The drug is used in adults in the complex treatment of diseases accompanied by secondary immunodeficiency states: - acute and chronic purulent-inflammatory diseases of the skin and soft tissues, including purulent-septic postoperative complications; - sexually transmitted infections (human papillomavirus infection, chronic); - herpetic infection (incl. with ophthalmoherpes); - psoriasis (including psoriatic); - lungs. Dosage regimen Licopid® is administered orally on an empty stomach, 30 minutes before meals. Elderly patients are recommended to start treatment with half doses (1/2 of the therapeutic dose), in the absence of side effects, increasing the dose of the drug to the required therapeutic dose. If a drug dose is missed, if no more than 12 hours have passed from the scheduled time, the patient can take the missed dose; If more than 12 hours have passed from the scheduled time of administration, you must take only the next dose according to the schedule and not take the missed one. Purulent-inflammatory diseases of the skin and soft tissues, acute and chronic, severe, including purulent-septic postoperative complications: 10 mg 1 time / day for 10 days. Herpetic infection (recurrent course, severe forms): 10 mg 1 time / day for 6 days. For ophthalmoherpes: 10 mg 2 times a day for 3 days. After a break of 3 days, the course of treatment is repeated. Sexually transmitted infections (human papillomavirus infection, chronic): 10 mg 1 time/day for 10 days. Psoriasis: 10–20 mg 1 time/day for 10 days and then five doses every other day, 10–20 mg 1 time/day. For severe psoriasis and extensive lesions (including psoriatic): 10 mg 2 times a day for 20 days. Pulmonary tuberculosis: 10 mg 1 time/day for 10 days. Side effects Often (1–10%) – arthralgia (joint pain), myalgia (muscle pain); at the beginning of treatment, there may be a short-term increase in body temperature to subfebrile values ​​(up to 37.9°C), which is not an indication for discontinuation of the drug. Most often, the side effects described above are observed when taking Lykopid® tablets in high doses (20 mg). Rarely (0.01-0.1%) – a short-term increase in body temperature to febrile values ​​(>38.0°C). If body temperature rises >38.0°C, antipyretics can be taken, which does not reduce the pharmacological effects of Lykopid® tablets. Very rarely (<0.01%) – . Если любые из указанных в инструкции побочных эффектов усугубляются или пациент заметил любые другие побочные эффекты, следует сообщить об этом врачу. Противопоказания к применению - повышенная чувствительность к глюкозаминилмурамилдипептиду и другим компонентам препарата; - беременность; - период лактации (грудного вскармливания); - детский возраст до 18 лет; - аутоиммунный тиреоидит в фазе обострения; - состояния, сопровождающиеся фебрильной температурой (> 38°C) at the time of taking the drug; - rare congenital metabolic disorders (alactasia, galactosemia, lactase deficiency, lactose intolerance, sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption); - use for autoimmune diseases is not recommended due to the lack of clinical data. Likopid® 10 mg is used with caution in elderly people, strictly under the supervision of a physician. Use during pregnancy and breastfeeding Taking Licopid® 10 mg is contraindicated for women during pregnancy and breastfeeding. Special instructions When starting to take the drug Likopid® 10 mg, there may be an exacerbation of the symptoms of chronic and latent diseases associated with the main pharmacological effects of the drug. In elderly people, Licopid® 10 mg is used with caution, strictly under the supervision of a physician. Elderly patients are recommended to start treatment with half doses (1/2 of the therapeutic dose), in the absence of side effects, increasing the dose of the drug to the required therapeutic dose. The decision to prescribe Licopid® tablets 10 mg to patients with a combination of diagnoses of psoriasis and gout should be made by a doctor when assessing the risk/benefit ratio, due to the potential risk of exacerbation of gouty arthritis and joint swelling. If the doctor decides to prescribe the drug Likopid® tablets 10 mg in a situation where the patient has a combination of diagnoses of psoriasis and gout, treatment should begin with low doses, in the absence of side effects, increasing the dose to a therapeutic one. Each Licopid® 10 mg tablet contains sucrose in the amount of 0.001 XE (bread units), which should be taken into account in patients with. Each Licopid® 10 mg tablet contains 0.184 grams of lactose, which should be taken into account by patients suffering from hypolactasia (lactose intolerance, in which the body experiences a decrease in the level of lactase, the enzyme necessary to digest lactose). Influence on the ability to drive vehicles and operate machinery. Does not affect the ability to drive vehicles and complex mechanisms. Overdose Cases of drug overdose are unknown. Symptoms: based on the pharmacological properties of the drug, in case of overdose, a rise in body temperature to subfebrile (up to 37.9 ° C) values ​​may be observed. Treatment: if necessary, symptomatic therapy (antipyretics) is carried out, sorbents are prescribed. A specific antidote is unknown. Drug interactions The drug increases the effectiveness of antimicrobial drugs, and there is synergism with antiviral and drugs. Antacids and sorbents significantly reduce the bioavailability of the drug. GCS reduce the biological effect of the drug Likopid®. Conditions and periods of storage The drug should be stored in a dry place, protected from light, out of reach of children at a temperature not exceeding 25°C. Shelf life – 5 years. Do not use after expiration date. Conditions for dispensing from pharmacies The drug is dispensed with a prescription.

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Reviews of the use of tablets immunomodulatorLycopid:

I have low immunity, and the doctor prescribed me the immunomodulator “Likopid”. The medicine is sold in tablets, the price is high, and this is the only disadvantage. The effect does not appear immediately, the effect is cumulative. I took three courses, only after that I noticed that my immunity had become stronger - I endured the cold autumn and winter calmly, and never got sick, which is an amazing and rare occurrence for me!

Anna, 37 years old

At first, my relationship with this immunomodulator did not work out. When I started taking the medicine prescribed to me, I did not find any positive effect. After some time, I took another course of Lykopid, and began to feel that my health began to improve. Then I learned from the doctor that the drug does not act immediately, first the medicinal substances accumulate, and only then they strengthen the immune system. This happened in my case too; I haven’t been sick during the cold season for several years now.

Oleg, 43 years old

Arbidol

® – proven protection against colds and flu!

is an antiviral drug with moderate effects. Arbidol is used as a therapeutic and preventive measure for severe viral diseases (acute respiratory infections, influenza, bronchitis, etc.).

I have a large family, and every year we use Arbidol to prevent influenza and ARVI diseases. Capsules for children and adults with different dosages are sold - this is a big plus, because you want to protect children without side effects. We use it as a preventive measure, the effect is good - none of the family members have gotten sick in two years. The drug is inexpensive - this is also a plus, it helps to avoid both the disease itself and expensive treatment.

Olga, 40 years old

"Arbidol", of course, is a well-known and time-tested medicine. About ten years ago, my doctor recommended that I use this immunomodulator for prevention, and make it a rule. During all this time I have never regretted this advice. Now this is my little tradition: when autumn comes, I go to the pharmacy and take Arbidol! By the way, I get sick very rarely.

Innocent, 39 years old

Amiksin

Amiksin is a powerful antiviral and immunomodulatory agent.

Amiksin is an antiviral drug with a strong effect. The immunomodulator Amiksin is used in the treatment of hepatitis A, B, C and various viral infections, including influenza, acute respiratory infections, and pulmonary diseases. Children can take Amiksin no earlier than 7 years old - the effect is powerful; before this age can have a destructive effect on the developing immune system.

Reviews of the use of Amiksin tablets:

I live in the south of Russia, where the climate is mild; I once went to visit relatives in Yaroslavl in winter and almost immediately fell ill. High temperature, weakness - in a word, flu. Within an hour after taking the first Amiksin tablet, the temperature almost returned to normal, and three days later I forgot about the illness! But it must be remembered that the medicine is strong, children should be given only a small dosage and consult a doctor first.

Antonina, 41 years old

I became acquainted with this immunomodulator almost two years ago, when I was sick several times in winter and spring. At this time I had to travel around the country in connection with my work. The infection hit me powerfully and knocked me off my feet. A friend bought the drug after consulting with the seller at the pharmacy. I took only three tablets and was cured of the disease! Already on the second day I felt so healthy that I was able to return to work. Then I found out that this drug is contraindicated for those who are allergic to the constituent substances. But Amiksin really helped me!

Nikolay, 49 years old

Amiksin - instructions for use

Release form, composition and packaging Orange film-coated tablets, round, biconvex; on the cross section - the core is orange, minor darker or lighter inclusions are allowed. 1 tab. tilorone (tilaxin) 125 mg Excipients: potato starch - 46 mg, microcrystalline cellulose - 120 mg, povidone (povidone K30) - 3 mg, stearate - 3 mg, croscarmellose (croscarmellose sodium) - 3 mg. Shell composition: hypromellose (hydroxypropyl methylcellulose) – 6.81 mg, titanium dioxide – 3.563 mg, macrogol (polyethylene glycol 4000) – 0.913 mg, polysorbate 80 (Tween 80) – 0.114 mg, quinoline yellow dye (E104) – 0.247 mg, sunset yellow dye (E110) – 0.353 mg. 6 pcs. – blister contour packages (1) – cardboard packs. 6 pcs. – blister contour packages (2) – cardboard packs. 10 pieces. – blister contour packages (1) – cardboard packs. 10 pieces. – blister contour packages (2) – cardboard packs. 6 pcs. – polymer jars (1) – cardboard packs. 10 pieces. – polymer jars (1) – cardboard packs. 20 pcs. – polymer jars (1) – cardboard packs. Pharmacological action Low molecular weight synthetic interferon inducer that stimulates the formation of alpha, beta, gamma interferons in the body. The main structures that produce interferon in response to the administration of tilorone are intestinal epithelial cells, hepatocytes, T-lymphocytes, neutrophils and granulocytes. After taking the drug orally, the maximum production of interferon is determined in the sequence intestine-liver-blood after 4-24 hours. Amiksin® has an immunomodulatory and antiviral effect. Induces the synthesis of interferon in human leukocytes. Stimulates bone marrow stem cells, depending on the dose, enhances antibody formation, reduces the degree of immunosuppression, restores the ratio of T-suppressors and T-helpers. Effective against various viral infections (including those caused by influenza viruses, other pathogens of acute respiratory viral infections, viruses, herpes). The mechanism of antiviral action is associated with inhibition of the translation of virus-specific proteins in infected cells, as a result of which viral reproduction is suppressed. Pharmacokinetics Absorption After taking the drug orally, tilorone is rapidly absorbed from the gastrointestinal tract. Bioavailability is about 60%. Distribution: Binding to blood plasma proteins – about 80%. Metabolism and excretion Tiloron does not undergo biotransformation and does not accumulate in the body. It is excreted almost unchanged in feces (about 70%) and urine (about 9%). T1/2 is 48 hours. Indications In adults - for the prevention and treatment of influenza and ARVI; - for the treatment of viral hepatitis A, B and C; - for the treatment of herpes infection; - for the treatment of cytomegalovirus infection; - as part of complex therapy of allergic and viral encephalomyelitis (including disseminated encephalomyelitis, leukoencephalitis, uveoencephalitis); - as part of complex therapy of urogenital and respiratory diseases; - as part of complex therapy of pulmonary tuberculosis. In children over 7 years of age - for the treatment of influenza and ARVI. Dosage regimen The drug is taken orally after meals. In adults, for nonspecific viral prevention, the drug is prescribed at a dose of 125 mg once a week for 6 weeks. Course dose – 750 mg (6 tablets). When treating a viral infection, the dose of the drug on the first day is 125 mg 2 times a day, then switch to taking 125 mg after 48 hours. The course of treatment is 1.25 g (10 tablets). When treating acute B, in the initial phase of treatment on the first and second days, the dose of the drug is 125 mg/day, and then 125 mg after 48 hours. The course of treatment is 2 g (16 tablets). In case of protracted hepatitis B, on the first day the dose of the drug is 125 mg 2 times a day, then 125 mg after 48 hours. The course dose is 2.5 g (20 tablets). For chronic hepatitis B in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the daily dose is 250 mg, then switch to taking 125 mg after 48 hours. In the continuation phase of treatment, the total dose ranges from 1.25 g (10 tablets) to 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week. The course dose of Amiksin varies from 3.75 to 5 g, the duration of treatment is 3.5-6 months, depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process. In acute cases, on the first and second days of treatment, Amiksin® is prescribed at a dose of 125 mg/day, then 125 mg after 48 hours. The course dose is 2.5 g (20 tablets). For chronic in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the drug is taken at a dose of 250 mg/day, then 125 mg after 48 hours. In the continuation phase of treatment, the total dose is 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week. The course dose of Amiksin is 5 g (40 tablets), the duration of treatment is 6 months, depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process. For complex therapy of neuroviral infections - 125-250 mg/day in the first two days of treatment, then 125 mg after 48 hours. The dose is set individually, the duration of treatment is 3-4 weeks. For the treatment of influenza and other acute respiratory viral infections in the first 2 days of illness, Amiksin® is prescribed at a dose of 125 mg/day, then 125 mg after 48 hours. The course dose is 750 mg (6 tablets). To prevent influenza and ARVI, Amiksin® is prescribed at a dose of 125 mg once a week for 6 weeks. Course dose – 750 mg (6 tablets). For the treatment of herpetic, cytomegalovirus infections, the dose of the drug in the first 2 days is 125 mg, then take 125 mg every 48 hours. The course dose is 1.25-2.5 g (10-20 tablets). For urogenital and respiratory infections, Amiksin® is prescribed at a dose of 125 mg/day for the first 2 days, then 125 mg every 48 hours. The course dose is 1.25 g (10 tablets). For complex therapy of pulmonary tuberculosis, in the first 2 days the drug is prescribed at 250 mg/day, then 125 mg every 48 hours. The course dose is 2.5 g (20 tablets). For children over 7 years of age with uncomplicated forms of influenza or other acute respiratory viral infections, the drug is prescribed in a dose of 60 mg (1 tablet) 1 time/day after meals on the 1st, 2nd and 4th day from the start of treatment. Course dose – 180 mg (3 tablets). If complications of influenza and other acute respiratory viral infections develop, the drug is taken 60 mg 1 time / day on the 1st, 2nd, 4th, 6th day from the start of treatment. Course dose – 240 mg (4 tablets). Side effects From the digestive system: symptoms of dyspepsia are possible. Other: short-term chills and allergic reactions are possible. Contraindications for use: pregnancy; - period of breastfeeding; - children under 7 years of age; - increased sensitivity to the drug. Use during pregnancy and breastfeeding Amiksin® is contraindicated for use during pregnancy and breastfeeding. Use in children Contraindication: children under 7 years of age. Special instructions Amiksin® is compatible with antibiotics and traditional treatments for viral and bacterial infections. Overdose To date, cases of overdose of the drug Amiksin® are unknown. Drug interactions No clinically significant drug interactions between Amiksin and antibiotics and traditional treatments for viral and bacterial infections have been identified. Conditions and periods of storage The drug should be stored out of the reach of children, in a dry place, protected from light at a temperature not exceeding 30°C. Shelf life – 3 years. Conditions for dispensing from pharmacies The drug is available without a prescription.

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Lymphomyosot

Lymphomyosot is a strong homeopathic remedy with immunomodulator properties.

Lymphomyosot is a homeopathic remedy with immunomodulator properties. Lymphomyosot improves the absorption of all medications, in many cases making it possible to reduce their dosage and prevent side effects. Lymphomyosot also fights edema well, has a lymphatic drainage effect, normalizing the exchange of fluids in the human body.

In addition to the effect of activating metabolic processes and strengthening the ability of the immune system to resist, Lymphomyosot removes harmful chemical compounds from the body. Used to treat diseases of the ENT organs, skin diseases, tumors, asthenia, etc.

Lymphomyosot is contraindicated in the presence of diseases of the thyroid gland and liver.