All this, in turn, is caused by a number of possible reasons, which provokes the rapid development of an aggressive state, often underlying the formation of mental disorders and nervous exhaustion.
Symptoms of increased excitability
Increased excitability V modern world not such a rare problem. People encounter it different ages. It can manifest itself to a greater or lesser extent, but in any of these cases it significantly affects a person’s condition, his worldview and self-perception, often leading to serious psycho-emotional and mental disorders.
To better understand whether you suffer from increased excitability, you should pay attention to your behavior and attitude towards certain things. As a rule, a lot in your life changes when overexcitability takes over you completely.
1. Sleep problems begin. Now it is normal for you to wake up at night and have nightmares, followed by painful falling asleep and tossing and turning in bed. Often you cannot even fall asleep, you feel either hot or cold, and are unable to find a comfortable position.
2. Arise eating disorders. You either refuse to eat or cannot leave the refrigerator. As a rule, the latter is accompanied by serious weight gain and the development of depression against the background of a strong increase. There are also frequent cases of the formation of bulimia against the background of increased excitability and strengthening of the depressive state.
3. Minor difficulties, obstacles, disruptions in plans unsettle you. At the same time, you either withdraw into yourself or openly express your anger, are ready to cross out the whole day because of one small trouble, and tend to blame everyone around you for what happened.
4. You become very vulnerable and suspicious - any careless word can provoke aggression, crying, hysteria.
5. Everything annoys you! The jangling of keys in your pocket, an incorrectly parked car, groceries arranged carelessly in the refrigerator, the smile of your interlocutor, the weather, and so on.
6. You have stopped controlling yourself. Sometimes you may catch yourself laughing unreasonably loudly or talking in a raised voice. Most likely, at such moments you no longer hold back your words and express your dissatisfaction even when it is not very appropriate.
7. Problems with memory and reaction appear. It becomes more difficult to communicate with people in general.
8. Often the world in this state seems hostile. If you have no friends, everyone goes against you.
9. There is a desire to get away from everything and everyone, to hide alone so that no one touches you.
10. As additional symptom Immunity decreases, digestion is disrupted, and you begin to get sick often.
Causes of increased excitability
The main factor in the development of increased excitability is extreme fatigue of the body. When all its resources are depleted, natural defensive reaction, the goal of which is to protect a person from negative influence from the outside, so movements become abrupt and the level of aggressiveness increases. Added to overwork is stress and the development of depression. With regular stress exposure, the nervous system is forced to work in emergency mode, experiencing overload. This becomes the impetus before the formation prolonged depression, which in turn provokes a person’s desire to get away from everything as far as possible.
Excessive use foods such as red meat, sugar, and caffeine over time damage digestion and the central nervous system. If the first one fails, disturbances occur in the production of pancreatic and thyroid gland. If the second fails, the transmission of nerve impulses is disrupted. Taken together, this gives rise to problems that lead to the development of human overexcitability.
Chronic lack of sleep, overwork, fatigue, excessive use of the computer, passion for computer games, addiction to the phone and TV - all these are the reasons for the appearance of increased excitability!
One of the main reasons for its development is also addiction to alcohol, smoking, narcotic substances, which may include antidepressants, as well as a number of other addictions.
IN childhood A frequent impetus for the development of increased excitability is the syndrome of hyperactivity and lack of attention. Unfortunately, it is not always possible to get rid of it completely, and the syndrome passes into the life of an adult, where it behaves unpredictably. Against the background of this neurological disease, overexcitability can be hidden or overt. And each is dangerous in its own way. In the first case, the person goes out due to emotional burnout, quickly loses working capacity, is prone to mental disorders and has a very difficult time getting along with people due to isolation. In the second case, the person is openly aggressive, irritable, does not get along with people due to the complexity of his character, is often dissatisfied with little things, and is prone to arguments and outbursts of rage. In both cases, people remain very susceptible to the influence of others.
How to deal with increased excitability
Home remedies for overexcitability
At home, a person with increased excitability can help himself in several ways.
1. Relaxing baths. Every 2-3 days, take baths with decoctions of chamomile, sage, thyme, lemon balm, motherwort, valerian root, juniper. They can be combined in one composition or used separately. After the procedure, you must go to bed immediately. The room should have a comfortable temperature and fresh air!
2. Instead of black, green tea and coffee, drink herbal teas with chamomile, thyme, lemon balm, mint, motherwort. They will help the nervous system recover, relieve tension, remove toxins from the body and normalize sleep.
3. Do morning exercises, do stretching, yoga, dance! Movement is life not only for the muscle corset, but also for nerve cells. Regular exercise, especially with positive or relaxing music, can improve electrical impulses entering the brain and normalize the state of increased excitability.
4. Eliminate irritating factors. If you realize that there are a lot of things in your room that irritate you and that you can’t concentrate, then immediately or gradually change everything in a way that suits you. Get out of sight the things that bother you the most! And, of course, do not forget about regular cleaning - a mess does not contribute to recovery.
5. Meditation and correct breathing. Regular practices teach you to control your consciousness and keep your emotions in your hands.
To all this, it’s good to add a visit to the pool and periodic massage from a professional, who will help you get physical relaxation.
Medicine against increased excitability
An important element Correction of increased excitability is a visit to a neurologist! Since this problem can be caused by serious deviations in the work of the central nervous system, it is important to exclude the development of the disease before engaging in treatment. In some cases, the doctor prescribes normalization of sleep and rest patterns, diet and physical activity, walks. But the basic approach does not always work, especially if we are talking about chronic condition. Then medications and supportive drugs are used, including mild sedatives, vitamins, nootropics, which allow you to correct nerve impulses and provide the brain with adequate nutrition.
Some of the common remedies are a variety of magnesium, potassium, vitamin C, Pantocalcin, Tenoten, Novopassit and other medications.
Zinaida Rublevskaya
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A person is constantly faced with emotions and various conditions. Now he is irritated, now cheerful, now calm. He observes similar states in other people. Sometimes your mood can change right before your eyes. This is facilitated by the excitability of the nervous system, which is influenced by factors environment. The topic of arousal and the influence of excitability on it will be considered.
What is excitability?
What is excitability? This concept includes the characteristic of a person moving into excited state under the influence of external stimuli. Excitation of the nervous system is the response of nerve cells to irritating stimuli and their entry into the brain, which provokes a corresponding state.
All people varying degrees excitability. Some are difficult to excite, others are easily excitable. The faster the nervous system is excited, the more this indicates various disorders in it.
Excitability is a consequence constant pressure, problems and stress on a person. Concerns, difficulties, tasks, troubles and other problems cause nervous tension inside. The more they accumulate, the more excitable a person becomes. Sometimes this leads to nervous breakdown, exhaustion. Some people develop neuroses based on constant excitability.
No person is free from stressful situations. Even young children constantly have situations when they begin to worry, fear, worry. Even if a person is able to withstand a stressful situation, he is still susceptible to such manifestations as irritability, aggression, nervousness, and anxiety. These experiences affect his productivity as well as behavior. When contacting other people, a person in a state of excitability often provokes conflicts. This negatively affects his quality of life.
Why does excitability occur? This is due to significant factors that a person pays attention to. If the situation involves the loss of something valuable to a person, then the level of his excitability will be much higher than an event when grief happens to other people.
Should be tracked this state. If this doesn’t work, then you can seek help from a psychotherapist on the website. It would be a mistake to think that you can cope with a nervous state with alcohol or cigarettes. In fact, this requires special techniques that directly affect the psyche.
You should not watch negative films (horror films, action films, news), or concentrate on something bad. It is better to think about good things that will calm and increase the stability of the nervous system. Psychologists also recommend using the following practices:
- Yoga.
- Meditation.
- Walks in the park.
- Aerobics.
Extremely severe cases You can resort to sedatives that relieve excitement of the nervous system.
Increased nervous excitability
Quite dangerous and favorable for increased nervous excitability becomes the environment of big cities. Here, a person is constantly accompanied by stress. Household worries, work problems, interpersonal conflicts that arise at every step - all this leads to stress, which affects the nervous state.
It is not surprising that people in big cities suffer more and more from various nervous disorders. Various factors affect a person every day, which causes increased nervous excitability. It often occurs not only in adults, but also in adolescents and children.
Increased nervous excitability can be determined by the following signs:
- Impaired eye movement.
- Lost in space.
- Lost in time.
- Asymmetry of the muscles on the face.
- Irregular headaches.
- Lack of concentration.
- Clumsiness in movements.
- Slowness of thinking.
Also, increased excitability can be recognized by the fact that previously a person calmly reacted to some stimuli, but now they cause him irritation. The more impaired the function of nervous stability, the faster man gets irritated and becomes aggressive when presented with petty stimuli.
Factors that provoke the development of nervous excitability are psychological reasons:
- Problems at work.
- Conflicts with loved ones.
- Lack of support.
- Loneliness.
- Invasion of personal space.
- Lack of personal space.
- Large crowd of people.
- Losses, etc.
The person doesn’t get enough sleep, eats poorly and hardly gets any rest. He is constantly immersed in his own problems, which he tries to solve without achieving the desired result. All this provokes emotional exhaustion, which is expressed by outbursts with people with whom we previously had good relationships.
In rare cases, causes of increased nervous excitability include:
- Hereditary predisposition.
- Metabolic failure.
- Infections.
- Hormonal changes.
- Mental problems: neuroses, schizophrenia, psychopathy.
Sometimes anxious and suspicious thoughts are added to all the reasons described above. A person, based on his irritated state, scrolls bad thoughts in his head for a long time, which prevent him from resting, falling asleep, eating, etc. Absence good rest and nutrition leads to even greater irritability, which starts the mechanism in a circle.
Here psychologists direct their efforts to eliminate the cause that provoked excitability. If an appointment is necessary sedatives, then they must be registered.
Excitability and arousal
It is not always necessary to talk about excitability as exclusively negative reaction body. The body does not have bad qualities, they are just sometimes used incorrectly by a person. Excitability is the property of the nervous system to conduct impulses to specific organs, changing their condition and increasing their performance. In some cases it's about excitement.
We can talk about sexual excitability, which is well developed in men. There are many discussions going on here, one of which concerns the issue of polygamy of the stronger sex. Why can't men be faithful to only women? Many refer to the instinctive desire of the stronger sex to reach the peak of pleasure - ejaculation, which is significantly different from female excitability.
The amount of sex becomes important for men, where they reach the peak of pleasure. Women care about other things – attention, affection, tenderness. That's why it becomes important quality intimacy.
Excitability can be not only sexual. Stimuli can be sent via nerve cells To various bodies which should be activated. This often happens in a state of " full readiness"when it is necessary to repel the attack of infection, remove it from the body foreign bodies, enhance your functionality in order to replenish the energy expended by a person, etc.
Bottom line
The excitability of the nervous system plays important role– it instantly reacts to various stimuli that make the body ready to perform tough and targeted actions. People often talk about the negative side of excitability, which manifests itself in fatigue, dissatisfaction with life, and bad emotions. However, excitability does not always perform a negative function. It often performs exclusively a mobilization function in order to eliminate the negative, which leads to a positive outcome.
Each person has their own level of excitability. Much depends on the structural features of the nervous system. This should also include each person’s ideology and character traits. All this together affects how easily he can be pissed off.
Character qualities, behavior and a person’s attitude to the circumstances of the world around him influence how excited he is. If it's not about psychological factors, and about physiological ones, then we talk about excitation - the accumulation of energy in one area in order to solve a problem or eliminate a difficulty.
Unfortunately, such a phenomenon as increased nervous excitability has become the norm today. This problem occurs in both one-year-old infants and older adults.
If you have become distracted, uncollected, have poor orientation in time and space, and experience regular headaches - think about it. With a high probability, these signs signal that your body has been overtaken by a syndrome of increased excitability, which can lead to the formation of neuroses. What could be the reason of this disease and how to get rid of it?
So, increased emotional excitability- This is one of the most common disorders of the nervous system. Surely you know firsthand how even the best self-control can break under the pressure of daily problems. All of them put pressure on our health, gathering, like puzzles, into a huge lump of psychological complications.
The reasons that you have increased excitability of the nervous system can be very diverse - frequent stress at work and at home, constant lack of sleep and susceptibility to nervousness and irritation. In most cases, these factors can manifest themselves in conflicts with other people, making it difficult to live full life. In addition, the syndrome of increased nervous excitability can affect a person with an anxious and suspicious psychotype.
Be that as it may, the solution to the problem cannot be postponed
According to statistics, every fifth person experiences this disease. If you notice unreasonable tearfulness, aggression, touchiness, and a desire to tear to pieces anyone who dares to touch you, it’s time to start treating increased excitability. It’s worth saying right away that frequent smoking breaks and alcohol will only aggravate the unpleasant condition.
- Help in the fight against similar condition not complicated psychological techniques. For example, put your information background in order - protect yourself from various crime stories and exciting news programs.
- Focus on positive emotions, discarding negative energy.
- Try aerobic exercise - yoga, sports aerobics and walking fresh air can be of great help to you.
- Often the body cannot restore individual anti-stress mechanisms without the use of special sedatives recommended for both men and women.
One of these is NERVOLEK. It does not cause addiction or drowsiness, and does not disrupt the course of processes in the body as intended by nature. Calm, constructive and soberly assessing the situation - this is exactly how the Universe created people. NERVOLEK does everything to return a person to his natural state. Be healthy!
Increased excitability of the nervous system is one of the most common disorders. It occurs in older people, young people, and even children.
Causes of increased nervous excitability
If minor everyday problems cause a violent reaction, everything irritates, a person becomes aggressive and uncollected, then these symptoms signal that you should immediately pay attention to the state of the nervous system.
Excessive excitability of the nervous system is observed in 20% of the population. This figure worries doctors, since the number of people suffering from nervous disorders is growing rapidly from year to year. This is not surprising, because modern life filled with stress, especially in major cities: emotional overload at work, lack of sleep, crowds of people on public transport, traffic jams, constant shortage time, streams of negative information that are splashed out on viewers by television channels, many hours of computer use - all these factors undermine mental health. Family troubles, heavy study load, poor nutrition, strict diets, computer games aggravate the problem.
Nervousness and irritability can develop under the influence hereditary predisposition, are provoked by metabolic disorders, hormonal changes in the body, infections. Sometimes increased nervous excitability may indicate the presence of more serious problems: depression, neuroses, psychopathy, schizophrenia. It is also a companion to alcoholism and drug addiction, especially during periods of withdrawal syndrome.
Manifestation of disorders of the nervous system
People with increased nervous excitability are characterized by conflict, irritability, and impaired temporal and spatial orientation. They get nervous over little things, lash out at loved ones and subordinates, and swear in public transport and in queues. Many of them complain about periodic causeless headache, nightmares, attacks of self-pity, tearfulness, melancholy.
Among external signs asymmetry of the facial muscles and movement disturbances are observed eyeballs. The person fusses, makes impulsive movements indicating motor excitement, and talks a lot. Children with increased excitability of the nervous system may have a slight delay in mental development.
The main sign of nervous system excitability is insomnia. We are not talking about those cases when a person occasionally cannot fall asleep for a long time after an emotional shock. Sleep disorders become systematic. If a person often cannot fall asleep for several hours, tossing and turning in bed, or wakes up for no reason in the middle of the night and does not close his eyes until the morning, this is a syndrome of increased nervous excitability.
Preventive measures
If a person is going through difficult times, or has some personal problems that make him nervous, the main thing is not to start looking for peace in alcohol and cigarettes. This will only lead to a gradual deterioration of the condition and aggravate the problem. It’s worth trying to switch your attention to other aspects of life, play sports, and walk in the fresh air as often as possible.
You should also reduce the amount of time spent at the computer and TV, and minimize the flow of negative information: crime reports, news about political and economic problems, conversations about diseases. You should definitely try to put your daily routine in order, sleep at least 7 hours a day.
If there is an opportunity to take a short vacation and relax for a few days in nature, then this opportunity simply cannot be missed. The state of all body systems largely depends on the nervous system. Increased excitability of the nervous system in itself is not serious illness, but if you do not pay any attention to it, it can lead to dire consequences.
How to deal with nervous excitability?
If serious problems arise with the functioning of the nervous system, you should consult a specialist.
He will hold necessary examination, will assign the appropriate drug treatment and will give related recommendations. Under no circumstances should you take antidepressants, tranquilizers or sleeping pills on your own, even if one of your friends took these drugs on the recommendation of a doctor for similar symptoms.
There are a number of means plant origin, which will have a beneficial effect on the state of the nervous system during periods of unrest, emotional stress, in stressful situations. These include drugs based on valerian and motherwort, which can be purchased in pharmacies without a prescription. Motherwort in the form of a tincture is taken alone or in combination with valerian. Prepared from dry raw materials herbal infusions and decoctions. Recently, motherwort can also be purchased in tablet form. Valerian preparations are also produced by the pharmaceutical industry in various forms.
Modern life with its high cost, intense rhythm, stress, in the wrong way life quickly exhausts the strength of oneself strong man. Unfavorable ecological situation also contributes to this.
It's understandable why we are all overtired, irritable and nervous. Our energy and will weaken, severe fatigue fetters us, interest in work, and in life itself and its joys, disappears. “We need to encourage ourselves, excite ourselves,” many of us think. And alcohol, tobacco, coffee and other various nervous poisons are used, finishing the destruction begun by overwork and an unhealthy lifestyle.
The result of this turns out to be very formidable. Our strength is weakening and we are hastening to take measures that for the most part are unsuccessful and fail to achieve their goals. Neither trips to the country, nor vacations, resorts, nor holidays in the countryside - nothing helps. You swallow all kinds of medicines prescribed by doctors, but nothing helps. You realize that you are becoming disabled and must leave the arena. You are joining the ranks of the huge mass of chronically ill people crowding in lines to see doctors and all the charlatans who promise healing. You believe, try and for the hundredth time you are convinced that you were deceived. Where to look for help? Where is the remedy that can provide healing? I will give you the answer to this question and show you how and with what you can restore your shattered nervous system and again become cheerful, energetic, cheerful, in a word, completely healthy person. Choose what suits you from the recipes below. They are simple, tested in my many years medical practice and give good results.
Honey and neuroses
Use only Bee Honey. Daily dose its 60-100 g (depending on your weight). At the same time, other sweets are excluded. Dilute honey in 500-800 ml boiled water room temperature and drink in 3-4 doses (150-200 ml each) during the day (last dose 30-40 minutes before going to bed) for neurosis. The condition improves after 1-2 weeks of such treatment (sleep normalizes, well-being, performance improves, etc.).
Herbal infusion and neurosis
Prepare the following collection: oregano, herb 30; blood-red hawthorn, herb 25; sweet clover, herb 20; valerian officinalis, roots 15; peppermint, leaves 10.
3 tbsp. l. dry crushed mixture, pour 0.5 liters of boiling water into a thermos, leave for half an hour or an hour, strain and drink 1/2 cup 3 times a day half an hour before meals for neuroses.
The infusion provides deep sleep, improves appearance, strengthens the nervous system.
Oregano infusion and increased nervous excitability
Prepare an infusion of oregano. Why do you need to take 3 tbsp. l. dry crushed herbs, pour 0.5 liters of boiling water in a thermos, leave for 1.5-2 hours, strain and drink half a glass 3 times a day half an hour before meals to calm the nervous system, improve sleep, and also for increased sexual excitability .
Oregano infusion has a fairly pronounced calming effect.
It should be remembered that oregano infusion should not be taken by pregnant women, as it stimulates contraction of the uterine muscles, which can lead to abortion.
Blackberry leaf decoction and increased nervous excitability
2-3 tbsp. l. dry crushed blue blackberry leaves, pour 0.5 liters of boiled water, boil over low heat for 8 minutes, leave for half an hour to an hour, strain and drink half a glass 2-3 times a day at increased irritability as a sedative, vitamin and tonic, as well as for insomnia.
Valerian infusion and nervous excitement
Take 2 tbsp. l. dry crushed rhizomes with valerian roots, pour 0.5 liters of boiling water into an enamel saucepan, leave for 15 minutes with the lid closed in a boiling water bath, leave until cool, then strain, squeeze the remaining raw materials into the resulting infusion, increase its volume boiled water to the initial level (0.5 l) and drink 1/3-1/2 cup after 30-40 minutes. after meals 2-3 times a day in states of nervous excitement, neurasthenia, menopausal disorders, insomnia due to nervous exhaustion and mental fatigue, headaches, neuroses of cardio-vascular system, autonomic neuroses and during treatment early forms angina pectoris, as well as for its prevention.
Ivan tea decoction and increased nervous excitability
3 tbsp. l. dry crushed fireweed herb, pour 0.5 liters of boiled water, bring to a boil and cook for 7-10 minutes. Then leave for 1-2 hours, strain and drink 1/2 cup 20-30 minutes before meals 2-3 times a day for increased nervous excitability, headaches and insomnia.
A decoction of fireweed tea has a calming and restorative effect.
Valerian, fennel and nervous excitement
Prepare the following mixture: valerian officinalis, rhizome with roots 50; common fennel, fruits 50.
2 tbsp. l. dry crushed mixture, pour 0.5 liters of boiled water, bring to a boil and cook over low heat for 7-10 minutes, then leave for half an hour to an hour, strain and drink 1 glass in the morning and evening with increased nervous excitability.
Watch, valerian, mint and nervous excitement
Prepare the following collection: three-leaf watch, 50 leaves; valerian officinalis, rhizome with roots 25; peppermint, leaves 25.
2 tbsp. l. pour 0.5 liters of dry crushed mixture into a thermos. boiling water, leave for half an hour, strain and drink half a glass 2-3 times a day at nervous excitement and insomnia.
Fragrant geranium and increased excitability of the nervous system
If you experience irritability, insomnia, increased arterial pressure, then get geraniums in your house. Inhaling its aroma, as evidenced by the results of some studies, allows you to strengthen the nervous system, normalize sleep and reduce high blood pressure within 2-3 weeks.
Scents and stress
If you are overly excited, then inhaling the aroma of oregano, lemon balm(melissa) or rose flowers will help you relieve nervous tension and calm down without resorting to pills. Inhaling the phytoncides of these plants is especially useful in the evening, after work. A very beneficial effect is also observed when inhaling the volatile substances of hop flowers, pine needles and geranium (stress is relieved, sleep improves, etc.).
Mint aroma and good mood
Inhaling the scent of peppermint helps create good mood. This has been known since ancient times. It’s not for nothing that people love and appreciate mint. This plant contains a lot essential oils, which help relieve spasms, expand coronary vessels and blood vessels of the brain, act as an analgesic, improve mood and sleep.
Phytoncides of oregano, lemon balm, pine needles and nervous disorders
For those experiencing symptoms nervous disorders And mental illness, it is useful to breathe in the phytoncides of oregano, lemon balm (melissa) and pine needles. This helps relieve stress, improves overall well-being, mood and sleep.
Inhaling the soothing volatile substances released by the above-mentioned plants is especially beneficial for children. school age. After all, in lessons they have to absorb a large amount of information every day, and stress during exam periods, and sometimes forced violations of the regime, also takes its toll. All these stressful conditions lead to poor health. Inhalation of odorous substances of oregano, lemon balm, pine needles - good prevention overstrain of the central nervous system.
Sweet clover tincture and increased excitability
Prepare an infusion of sweet clover. Why 2 tbsp. l. dry crushed sweet clover herb, pour 0.5 liters of boiling water into a thermos, leave for 1-2 hours, strain and drink 1/3-1/2 cup 2-3 times a day for increased excitability, menopausal neurosis, melancholy, neurasthenia, headaches pain accompanying hypertension and migraine.
Sweet clover infusion has an analgesic, sedative and antispasmodic effect.
An infusion of primrose flowers is a tonic for nervous weakness.
2-3 tbsp. l. dry crushed spring primrose flowers, pour 0.5 liters of boiling water into a thermos, leave for 1-2 hours, strain and drink 1/2 cup 3 times a day half an hour before meals at nervous weakness, insomnia, headaches, loss of strength, etc.
Valerian, hops and nervous excitement
Prepare the following mixture: valerian officinalis, rhizomes with roots 50; common hop, 50 fruits.
2 tbsp. l. pour 0.5 liters of the mixture into a thermos. boiling water, leave for 20-30 minutes, strain and drink 1 glass before bedtime for nervous excitement or insomnia.
Infusion of hops and neuroses
2 tbsp. l. dry crushed hop heads, pour 0.5 liters of boiling water into a thermos, leave for 1-1.5 hours, strain and drink 1/4 cup 3 times a day for 20-30 minutes. before meals with increased excitability, nervous fatigue, insomnia, as well as vegetative-vascular dystonia, menopausal disorders, frequent emissions and excessive sexual arousal.
An infusion of hop cones has a calming, antispasmodic and analgesic effect.
An overdose of hop cone infusion leads to a feeling of fatigue, headaches, abdominal pain, nausea and even vomiting. But if you take the drug in the doses recommended above, then side effects, as a rule, is not observed (sometimes only drowsiness during the daytime is possible, then you need to slightly reduce the dose).