Kudesan for children: instructions for use. Kudesan - a natural protector of children's health: a review

The state of the body directly depends on the activity of biochemical processes occurring in the cellular level. This also applies to the heart muscle. With a lack of certain substances, the metabolic processes in the myocardium. Cardiomyocytes suffer from a lack of oxygen, which affects the efficiency of the heart.

In order to avoid similar problems, and the drug Kudesan was created. Drops and tablets can be used in pediatric and therapeutic practice. There is another form - Kudesan forte. The active component of this drug is coenzyme Q10 (ubidecarinone or ubiquinone). This biologically active substance is a coenzyme that takes part in almost all metabolic processes.

Some diseases as well age-related changes in the body lead to a decrease in the content of coenzyme Q10 in cells, and the additional introduction of ubiquinone with the help of certain dosage forms allows you to fill the emerging deficit.

Mechanism of action

Coenzyme Q10 is present in all cells of the body. It is necessary for the normal occurrence of oxidative phosphorylation reactions. This is a process in which, as a result of oxidation, nutrients energy is released. It is stored by cells in the form of ATP (adenosine triphosphate), a universal energy source. Almost everything biochemical processes occur with the participation of ATP.

The main energy station of the cell is mitochondria - organelles in which oxidation processes occur. To carry out biochemical reactions, it is necessary to move electrons along the electron transport chain of proteins in the inner membrane of mitochondria. Electron transfer is carried out by coenzyme Q10.

Ubiquinone, which is part of the preparations Kudesan and Kudesan forte, has an antioxidant effect itself, and also restores the antioxidant properties of alpha-tocopherol (vitamin E). It fights lipid peroxidation, which produces free radicals that cause aging in the body. But unlike other antioxidants, ubiquinone can be synthesized inside the body from tyrosine and phenylalanine derivatives, as well as mevalonic acid.

Most coenzyme Q10 is found in the heart muscle. A deficiency of this substance can occur with genetic disorders. With age, the amount of ubiquinone in the body also decreases. In elderly people, its content in the myocardium is reduced by 40–60% compared to young people. The concentration of this coenzyme decreases in some diseases, mainly genetic.

With an increase in ubiquinone content, metabolic processes in the myocardium improve and tissue hypoxia decreases. The ischemic zone with insufficient blood supply to the heart muscle is reduced, and exercise tolerance is improved. The likelihood of QT interval prolongation is reduced, which reduces the risk of severe arrhythmias and sudden death.

Thus, we can highlight the main effects of Kudesan:

cardioprotective;
antihypoxic;
cardiotonic;
antioxidant;
immunostimulating;
adaptogenic.

About how a medicinal substance behaves in the human body, official instructions does not contain information.

Indications and use

According to the instructions, Kudesan can be used both for prophylactic purposes and for the treatment of certain diseases. Indications for adults and children are somewhat different.

Use in adults is possible with prophylactic and therapeutic purpose upon detection:

chronic cardiac failure (CHF), including those developed against the background of dilated cardiomyopathy;
interruptions in heart function;
coronary insufficiency – chronic ischemia myocardium (CHD), recently suffered a heart attack myocardium (during the rehabilitation period);
high blood pressure.

It is possible to prescribe this medicine during preoperative preparation if cardiac surgery is planned or coronary vessels. This could be coronary artery bypass surgery or correction of heart defects.

Use in children is possible for the following indications:

diseases of the cardiovascular system: failure heart rate, CHF with various pathologies hearts, preparation for surgical intervention regarding congenital valve defects;
diseases of the digestive system - chronic gastroduodenitis;
urological diseases - nephropathy that developed against the background of metabolic disorders; chronic inflammation kidney (pyelonephritis);
neurological problems – cardiopsychoneurosis, migraine attacks; severe genetic abnormalities such as tuberous sclerosis, MELAS syndrome, congenital myopathies, Leigh's syndrome, as well as dystrophic changes in muscles;
asthenic condition;
restoration of the body after severe surgery and severe illnesses.

At any age, the medicine can be used as additional source coenzyme Q10 to prevent its deficiency or compensate for deficiency. This excellent remedy for athletes, helping to quickly adapt to increased loads. In adults, it is preferable to use Kudesan forte.

The medicine must be taken in the first half of the day directly with meals. The entire dose is taken at once. Kudesan drops should be diluted with water before use, but you can use another drink for this. The dosage depends on the goals of therapy and age. Prophylactic doses less than therapeutic ones, which are used to treat diseases in the composition complex therapy. Take the drug for up to 2-3 months. The course can be repeated later.

Before starting use, be sure to consult a doctor and study the instructions in detail. Kudesan forte contains a high concentration, which should be taken into account during treatment.

Contraindications and side effects

There are few contraindications for prescribing coenzyme Q10 indicated in the instructions:

children under 1 year;
individual intolerance.

The tablet form is contraindicated for children under 3 years of age, and Kudesan forte is not used until 14 years of age. Caution is required if there is a tendency to increase blood pressure. It is not recommended to use the medicine for women during pregnancy, as well as during lactation, since the effect of the medicine in this category of patients has not been studied.

Treatment is usually well tolerated. In rare cases, undesirable complications of therapy, manifested by nausea, diarrhea and allergic reactions, are possible. Cases of overdose due to the use of the drug have not been recorded, which indicates its safety.

Interaction with other drugs

Kudesan forte, like the regular form of the drug, is compatible with most medications. When used simultaneously with warfarin, the effectiveness of the latter is reduced. During treatment, the potentiating effect of ubiquinone in relation to the following drugs should be taken into account:

ACE inhibitor – enalapril;
calcium antagonist - diltiazem;
B-blocker - metoprolol;
antianginal agents - nitrates.

It is not advisable to take Kudesan and Kudesan forte simultaneously with such groups of drugs as tricyclic antidepressants, cholesterol-lowering drugs (fibrates and statins), as well as B-blockers (anaprilin and its analogues, atenolol and metoprolol). This is due to the fact that these drugs reduce the level of ubiquinone in plasma, so the effectiveness of treatment decreases.

Release forms

The medicine is produced in Russia by JSC Akvion. For ease of use, several forms of the drug have been created: drops and tablets. Exists special combination ubiquinone with microelements, as well as a more convenient form - Kudesan forte.

Oral solution

The content of coenzyme Q10 in the solution is 30 mg/ml. This produces a 3% solution. The bottle, which looks like a dropper, contains 20 ml of solution. The shelf life is 2 years. Storage temperature should be between 15–25 °C. This form can be used in both adults and children over 1 year of age. Thanks to special technology, coenzyme Q 10 here has a water-soluble form, which allows this active substance to be better absorbed.

Children's tablets

Chewable tablets Kudesan for children contain 7.5 mg of ubiquinone and 1 mg of vitamin E. Approved for use in children from the age of three. The package contains 30 tablets that have a creamy taste. The daily dose is determined by the age of the child.

This option is more suitable for people suffering from pathologies of the heart and blood vessels. The composition additionally contains microelements: 97 mg of potassium and 16 magnesium. These substances are necessary for normal contraction heart muscle and conduction of nerve impulses. Microelements support elasticity vascular wall and help strengthen the myocardium.

This form can only be used in adults. The main indications, according to the instructions, are the prevention and treatment of diseases such as chronic coronary insufficiency(IHD), hypertonic disease, heart rhythm disturbances. But it is used not as a primary remedy, but as an addition to basic drug therapy. The package contains 40 tablets.

Strengthened formula

There is such a form of the drug as Kudesan forte. It is available in the form of drops and tablets. According to the instructions, it can be used in adults and children over 14 years of age. The main difference is the increased content of coenzyme Q 10. In tablet form there is 30 mg of ubiquinone, and 4.5 mg of vitamin E is added. One tablet satisfies daily requirement in coenzyme Q10 by 100%. The package contains 20 pieces.

Kudesan forte solution contains 60 mg of ubiquinone and 6.8 mg of vitamin E in 1 ml. The volume of the dropper bottle is also 20 ml. Due to the higher concentration of the active substance, fewer drops are required per dose, which is much more profitable than using a 3% solution.

Analogues

Coenzyme Q10 is also produced by other manufacturers:

Kudevita – capsules, Pik-Pharma (Russia);
Valeocor-Q10 – chewable tablets, ZiO-Zdorovye (Russia);
Doppelhertz Coenzyme-Q10 active – capsules, Queisser Pharma (Germany);

Kudesan drops 3%- a drug that normalizes myocardial metabolism, reducing tissue hypoxia. Ubidecarenone (coenzyme Q10, ubiquinone) is a natural substance that is a vitamin-like coenzyme. Ubidecarenone is an endogenous substrate, takes part in the transfer of electrons in the transport chain of redox processes, in the process of energy exchange, in the reaction of oxidative phosphorylation in the respiratory chain of cell mitochondria. Participates in the processes of cellular respiration, increasing ATP synthesis.
Has a clinically significant antioxidant effect. Protects lipids cell membranes from peroxidation.
Reduces the area of myocardial damage under conditions of ischemia and reperfusion. Ubidecarenone prevents QT interval prolongation and improves exercise tolerance.
Due to endogenous synthesis, 100% satisfaction of the body's need for coenzyme Q10 occurs only until the age of 20. The concentration of coenzyme Q10 decreases in elderly patients, as well as in various diseases in both adults and children.

Indications for use

Drops Kudesan intended for complex therapy of diseases of the cardiovascular system: adults: for coronary disease heart, chronic heart failure, arterial hypertension, arrhythmias; children from 1 year: for arrhythmia, asthenic syndrome, dilated cardiomyopathy, congenital myopathy.
To prevent coenzyme Q10 deficiency.

Mode of application

A drug Kudesan should be taken orally 1 time per day during a meal in the first half of the day, after dissolving in a small amount boiled water or other drink room temperature. In order to prevent and compensate for coenzyme Q10 deficiency, take in accordance with the recommendations outlined in Table 1.
Table 1

In complex therapy various diseases Kudesan should be taken depending on age for all stated indications in accordance with the recommendations set out in Table 2.
table 2

The duration of the course of use of the drug Kudesan is 2-3 months. Repeated courses - on the recommendation of a doctor.

Side effects

Possible allergic reactions. Very rare: nausea, diarrhea.

Contraindications

:
Hypersensitivity to the components of the drug, childhood up to 1 year are contraindications to the use of the drug Kudesan.
Use caution in case of arterial hypotension.

Pregnancy

:
A drug Kudesan It is not recommended for pregnant and lactating women due to the lack of sufficient experience in clinical use.

Interaction with other drugs

The simultaneous use of lipid-lowering drugs (statins, fibrates), beta-blockers (atenolol, metoprolol, propranolol), tricyclic antidepressants can lead to a decrease in the concentration of ubidecarenone in the blood plasma.
Ubidecarenone may reduce the effect of warfarin.
Ubidecarenone may potentiate the effects of diltiazem, metoprolol, enalapril and nitrates.

Storage conditions

Store in a place protected from light at a temperature of 15 to 25? C.
Keep out of the reach of children.

Release form

Kudesan - drops for oral administration 3%. 20 ml in light-protective (orange) glass bottles, equipped with polyethylene dropper stoppers and screw caps.

Compound

:
1 ml of drug Kudesan contains: active substance: ubidecarenone - 30 mg.

Main settings

Name:	KUDESAN DROPS
ATX code:	C01EB09 -

Most heart diseases are associated with disruption of activity within the organ - slow metabolism in muscles and tissues, tissue hypoxia, as well as atrophy of the heart muscle.

All this can lead to adverse consequences– myocardial infarction, heart failure, heart rhythm disturbances, etc. To eliminate such phenomena, the modern pharmaceutical market offers a universal natural preparation- Kudesan.

Kudesan is a natural medicine designed to eliminate tissue hypoxia, as well as normalize metabolism in the heart muscle. The main components of the composition are ubidecarenone (ubiquinone, coenzyme) and alpha-tocopherol (vitamin E).

The drug is produced in the form of tablets for adults and children, as well as in the form of drops.

Release form: for adults – Kudesan Forte 20 tablets, Kudesan (potassium and magnesium) – 30 tablets, for children 30 chewable tablets.

Drops 3%-6% aqueous solution presented in the form clear liquid with an orange tint. The liquid is poured into glass containers with a dispenser (dropper) of 15, 20, 30, 60 and 100 ml.

Tablets are available in round flat shape 20-30 pieces in one package, painted in pale orange. Tablets with potassium and magnesium are colored pink color. Available for children special tablets Chewable with a pleasant creamy taste.

Composition of the drug:

Substance	Kudesan Forte	Kudesan for children	Kudesan drops 3%	Kudesan drops 6%	Kudesan (potassium + magnesium)
1. Ubidecarenone	30 mg	7.5 mg	30 mg	60 mg	7.5 mg
2. Alpha tocopherol	4.5 mg	1mg	4.5 mg	6.8 mg	1 mg
3. Additional substances	Kollidon E; Aerosil; calcium stearate; cellulose; primelose; talc.	dextrose monohydrate; silica; magnesium stearate; povidone; talc; creamy flavor.	sodium benzoate; ascorbyl palmitate; lemon acid; cremophor.	sodium benzoate; macrogol glyceryl hydroxystearate; ascorbyl palmitate; lemon acid.	potassium – 97 mg; magnesium – 16 mg.

Kudesan 6% contains large quantity ubiquinone, so its intake must be agreed with a specialist.

Drug action

The drug belongs to the group of cardiac non-glycosides. When used, it has antioxidant, antihypoxic and cardiotonic effects.

Ubiquinone in the composition of the drug is a natural coenzyme that activates redox processes in tissues, accelerates energy metabolism, and also normalizes respiratory function all cells.

Ubiquinone has a powerful antioxidant effect - it protects cell walls from oxidation, and also promotes the activation of other antioxidants in the body. The coenzyme takes part in the synthesis of ATP (adenosine triphosphoric acid), and also prevents the development of atherosclerosis. Tocopherol in the drug activates the action of the coenzyme.

Coenzyme – natural substance, which the body synthesizes as a result of eating food. The human body produces ubiquinone in sufficient quantity V at a young age, after 20 years, the synthesis of ubiquinone slows down, its amount in the body decreases, which leads to weakened immunity, decreased performance, and fatigue.

The medication is able to compensate for the lack of coenzyme in the body, which makes it possible to effectively treat diseases of the heart and blood vessels and prevent the development of a heart attack.

Indications for use

The drug is used in the composition combination therapy heart diseases in adults:

IHD (coronary heart disease);
heart failure;
hypertension;
arrhythmias.

The drug is indicated for patients after a heart attack, as rehabilitation therapy, as well as for patients to prepare for heart surgery.

The medicine for children is used for gastroduodenitis, pyelonephritis, nephropathy and the following diseases nervous system:

vegetative - vascular dystonia;
asthenic syndrome;
Melas syndrome (mitochondrial encephalomyopathy);
tuberous sclerosis;
myopathies;
Leigh's syndrome;

The drug can increase performance and physical endurance, so it is often used by athletes as a dietary supplement (dietary supplement).

For children from one year of age and adults, the drug is prescribed to prevent coenzyme deficiency in the body.

Instructions for use

The drug in drops is taken orally, once a day, before meals, diluting the drops in a small amount of water. Accurate daily dosage The drug is prescribed by a doctor on an individual basis.

Dose of the substance for prophylactic purposes:

children from 1-3 years old – 3 drops once a day;
from 3-7 years – 4-5 drops once a day;
from 7-12 years – 10 drops once a day;
from 12 years and older – 15-25 drops.

Dose of the substance for medicinal purposes:

children from 1 year to 3 years – no more than 10 drops per day;
from 3 years to 7 years – 15 drops per day;
from 7 to 12 years – 20 drops per day;
from 12 years and older – 30-60 drops per day.

The therapeutic course is 2 months or more; in case of urgent need, the course is repeated at intervals of 2 months.

For Kudesan Forte, the dosage will be different, since this form contains an increased dose of ubidecarenone.

Dose of the substance in tablets:

Adults and children over 14 years of age – 1 tablet once a day.
Children from 3 to 7 years old - 1 t. per day, from 7 to 14 years - 2 t. per day.

Before using the medicine for preventive purposes, you should consult your doctor.

Contraindications

The substance is contraindicated for use in infants (under 1 year).

The drug is also contraindicated if the patient has: hypotension, acute glomerulonephritis, duodenal ulcers, hypersensitivity to elements of the drug.

Side effects and overdose

No cases of drug overdose have been identified. Side effects occur rarely, due to hypersensitivity to additional substances of the drug or as a result of disturbances in the gastrointestinal tract. More often side effects speakers:

nausea;
diarrhea;
intestinal colic;
allergies: rashes on the body.

The drug is well tolerated by both adults and children, so the above-described phenomena are rare in medical practice.

Use during pregnancy and lactation

Research results on the impact medicinal substance no effect on intrauterine development of the fetus. Therefore, it is not recommended for pregnant women to use the drug. Due to the lack of clinical data on the presence of ubidecarenone in breast milk, nursing women are advised to stop lactation while taking it.

Interaction with other medications

The medicinal substance can enhance the effect of the following drugs:

Metoprolol;
Diltiazem;
Enapril.

The use of drugs from the group of adrenergic blockers, antidepressants, as well as statins and fibrates in conjunction with the drug helps to reduce the level of coenzyme in the body and reduce the therapeutic effect.

special instructions

Doctors do not recommend taking alcoholic drinks during treatment. The medicine does not affect mental and physical activity, speed of reactions, attention - therefore the product is approved for use by vehicle drivers.

Price of the drug and its analogues

The cost of the drug depends on the form of release. Below is only the approximate cost of the medicinal substance; prices may vary in different pharmacy chains.

Kudesan Forte – 390 rubles;
Kudesan (drops 3%) – 280 rubles;
Kudesan Forte (6% drops) – 499 RUR;
Kudesan for children – 350 rubles;
Kudesan with potassium and magnesium – 361 rub.

Analogues are products with a similar effect, but with different active substances in the composition. These are:

Vazonit (tablets) – the active substance is meldonium dihydrate. Price – 280 rub.
Phosphaden (solution) – contains adenosine 5 monophosphoric acid. Price for one package – 76 - 80 rubles.
Ranexa (tablets) – contains ranolazine. Price for 1 package – 2978 rub.
Zithrom C (drops) – the main substance is citrom lyophysilate, prices – from 1170 rub. for 1 bottle of solution and from 1130 rub. for 5 ampoules.
Kuten (capsules) - contain coenzyme, price for a package of 30 capsules - from 200 rubles.
Kudevit (capsules) - contain coenzyme, price for a package of 30 capsules - from 300 rubles.
Valeocor Q 10 (chewable tablets) – contains coenzyme, one package costs about 200 rubles.

Prices in different pharmacy chains, as well as regions, may differ, so before buying the drug, you should familiarize yourself with all by similar means, form, as well as manufacturers, since prices for domestic medicines will differ from prices for foreign similar medicines.

Release form and composition

The medication is available in the form of an oral solution, tablets and chewable tablets for children.

1 ml of solution contains:

30 or 60 mg ubiquinone (coenzyme Q10);
4.5 or 6.8 mg vitamin E;
Excipients such as macrogol glyceryl hydroxystearate, sodium benzoate, ascorbyl palmitate, citric acid, purified water.

Each tablet contains:

30 mg ubiquinone;
4.5 mg vitamin E;
Excipients: pharmaceutical talc, Kollidon E, aerosil, calcium stearic E470, microcrystalline cellulose, primelose.

Each chewable tablet contains:

7.5 mg ubiquinone;
1 mg vitamin E;
Excipients.

Indications for use of Kudesan

The instructions for Kudesan indicate that this drug is prescribed to adults for the prevention and treatment of various diseases of the cardiovascular system (as part of complex therapy):

Chronic heart failure;
Coronary heart disease;
Myocardial infarction;
Arterial hypertension;
Arrhythmias.

This drug is also prescribed to patients during preparation for heart surgery.

Kudesan can be taken for prevention premature aging. It is recommended for elderly people to use it when increased fatigue and asthenia.

Clinical trials have shown the effectiveness of this medication for neurological and endocrine diseases. IN medical practice Cases have been recorded where, with the help of Kudesan, it was possible to prolong the life of cancer patients.

Kudesan is prescribed for children for the prevention and complex treatment:

Diseases of the cardiovascular system: chronic heart failure, arrhythmia, as well as during preparation for heart surgery (due to congenital or acquired defect);
Diseases gastrointestinal tract, in particular chronic gastroduodenitis;
Kidney diseases, including metabolic nephropathy and chronic pyelonephritis;
Diseases of the nervous system: migraine, Leigh's syndrome, muscular dystrophy, tuberous sclerosis, disorders of the autonomic nervous system, congenital myopathy, mitochondrial encephalomyopathy;
Asthenic syndrome.

For therapeutic and prophylactic purposes, children are recommended to take Kudesan to improve well-being, increase exercise tolerance, reduce fatigue, increase immunity, and normalize the activity of the cardiovascular system.

In addition, Kudesan is prescribed to both children and adults:

To increase the body’s adaptive capabilities to increased physical activity (when playing sports);
To compensate for deficiency and prevent deficiency of coenzyme Q10.

Contraindications

According to the annotation for the drug, the use of Kudesan is contraindicated:

Infants under 1 year in the form of drops;
For children under 3 years of age in the form of chewable tablets;
Children under 14 years of age in the form of tablets;
To all patients, if they have hypersensitivity to any component of the medication.

Carefully medicine used for arterial hypotension.

Method of application and dosage of Kudesan

Kudesan solution, according to the instructions, should be taken orally once a day in the morning during meals, dissolving the required number of drops in a small amount of water at room temperature.

For preventive purposes take:

2-4 drops – children from 1 year to 3 years;
4-8 drops. – children 3-7 years old;
8-12 drops. – children 7-12 years old;
12-24 drops. – from 12 years and adults.

In the treatment of various diseases as part of complex therapy:

4-10 drops – children from 1 year to 3 years;
10-16 drops. – children 3-7 years old;
16-20 drops. – children 7-12 years old;
20-60 drops. – from 12 years and adults.

The duration of treatment with Kudesan is 2-3 months, with repeated courses if necessary. For preventive purposes, it is recommended to take the drug twice a year for 2 months.

Kudesan tablets are prescribed to children over 14 years of age and adults, 1 pc. once a day.

Chewable tablets Kudesan should be used:

1 piece each – children 3-7 years old;
1-2 pcs. – children 7-14 years old;
2 pcs. – teenagers over 14 years old.

Side effects of Kudesan

Numerous reviews from patients who took Kudesan or gave it to their children indicate that this drug in the vast majority of cases is well tolerated and subject to the dosage regimen recommended by the doctor. side effects does not provide. In extremely rare cases, there are complaints of nausea and diarrhea, as well as allergic reactions caused by hypersensitivity to one or another component of the medication.

There have been no cases of overdose with Kudesan in medical practice.

special instructions

Kudesan potentiates the effect of nitrates, enalapril, diltiazem and metoprolol, and reduces the effect of warfarin.

At simultaneous use Kudesana with tricyclic antidepressants, beta-blockers and hypoglycemic agents in the blood plasma reduces the concentration of ubiquinone.

Analogues of Kudesan

With a similar active ingredient, you can also buy drugs such as Ubinon, Kudevita, Velokor-Q10.

Based on belonging to the same pharmacological subgroup and the similarity of the effects on the human body, Kudesan analogues can be considered the following drugs: Angiozil, Biosint, Hawthorn tincture, Vazomag, Deprenorm, Dibikor, Idrinol, Inosin-Eskom, Cardionat, Medarum, Mexicor, Midolat, Mildronate, Neoton, Orocamag, Predizin, Riboxin, Serotonin, Taufon, Trimet, Firazir.

Terms and conditions of storage

Kudesan can be stored for 2 years protected from direct sun rays and a dry place where the air temperature does not exceed 25 ºС.

In this article you can find instructions for use medicinal product Kudesan Q10. Feedback from site visitors - consumers - is presented of this medicine, as well as the opinions of specialist doctors on the use of Kudesan Q10 in their practice. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Kudesan Q10 if available structural analogues. Use for the treatment of heart disease, syndrome chronic fatigue And vegetative dystonia in adults, children, as well as during pregnancy and breastfeeding. Composition of the drug.

Kudesan Q10- a drug that normalizes myocardial metabolism and reduces tissue hypoxia. Ubidecarenone (coenzyme Q10, ubiquinone) is a natural substance that is a vitamin-like coenzyme. Ubidecarenone is an endogenous substrate that takes part in the transfer of electrons in the transport chain of redox processes, in the process of energy exchange, and in the reaction of oxidative phosphorylation in the respiratory chain of cell mitochondria. Participates in the processes of cellular respiration, increasing ATP synthesis.

Has a clinically significant antioxidant effect. Protects cell membrane lipids from peroxidation.

Reduces the area of myocardial damage under conditions of ischemia and reperfusion. Ubidecarenone prevents QT interval prolongation and improves exercise tolerance.

Due to endogenous synthesis, 100% satisfaction of the body's need for coenzyme Q10 occurs only until the age of 20. The concentration of coenzyme Q10 decreases in elderly patients, as well as in various diseases, both in adults and children.

Compound

Ubidecarenone (Coenzyme Q10) + Excipients.

Ubidecarenone (Coenzyme Q10) + vitamin E + excipients (Kudesan Forte).

Ubidecarenone (Coenzyme Q10) + Magnesium aspartate + Potassium aspartate + excipients (Kudesan with potassium and magnesium).

Indications

Adults

For prevention and as part of complex therapy of various diseases of the cardiovascular system:

chronic heart failure (including dilated cardiomyopathy);
IHD, incl. myocardial infarction (during the period of rehabilitation therapy);
arrhythmias;
arterial hypertension;
period of preparation for heart surgery (coronary artery bypass surgery, for heart defects).

Children over 1 year old

For prevention and as part of complex therapy:

diseases of the cardiovascular system: arrhythmias, chronic heart failure (including dilated cardiomyopathy), the period of preparation for heart surgery (congenital and acquired defects);
Gastrointestinal diseases: chronic gastroduodenitis;
kidney diseases: chronic pyelonephritis, metabolic nephropathy;
diseases of the nervous system (including hereditary neurodegenerative diseases): migraine, disorders of the autonomic nervous system (NCD), mitochondrial encephalomyopathy (MELAS syndrome), Leigh's syndrome, tuberous sclerosis, congenital myopathies, muscular dystrophies.

In the complex therapy of diseases associated with metabolic disorders:

asthenic syndrome;
recovery period after serious illnesses and surgical interventions.

Adults and children over 1 year old

for the prevention and replenishment of coenzyme Q10 deficiency;
used for chronic fatigue syndrome;
fights age-related changes;
to improve adaptation to increased physical activity in athletes.

Release forms

Drops for oral administration 3%.

Forte solution.

Chewable tablets 7.5 mg (for children).

Forte tablets, as well as with potassium and magnesium.

There are no other dosage forms such as skin cream or capsules. Coenzyme Q10 is used in cosmetology to produce hand or face cream, but there is no such form in the Kudesan product line.

Instructions for use and dosage regimen

Kudesan should be taken orally once a day during a meal in the first half of the day, after dissolving it in a small amount of boiled water or another drink at room temperature.

For the purpose of prevention, take for all stated indications depending on age:

age 1-3 years - average dose 2-4 drops;
age 3-7 years - average dose 4-8 drops;
age 7-12 years - average dose 8-12 drops;
children over 12 years of age and adults - an average dose of 12-24 drops.

In the complex therapy of various diseases, Kudesan should be taken depending on age for all stated indications:

age 1-3 years - average dose 4-10 drops;
age 3-7 years - average dose 10-16 drops;
age 7-12 years - average dose 16-20 drops;
children over 12 years of age and adults - an average dose of 20-60 drops.

The duration of the course of use of the drug Kudesan is 2-3 months. It is possible to conduct repeated courses on the recommendation of a doctor.

Forte tablets

Adults and children over 14 years of age: 30 mg/day (1 tablet of Kudesan Forte) 1 time per day with meals.

Tablets for children

For preventive purposes:

age 3-7 years - average dose 1 tablet per day;
age 7-14 years - average dose 1-2 tablets per day;
age over 14 years - average dose 2 tablets per day.

When used for therapeutic purposes, the dosage and course of administration are determined by the doctor.

Tablets with potassium and magnesium

Adults: 2 tablets 2 times a day with meals. Duration of use - 1 month.

Side effect

nausea;
diarrhea;
allergic reactions.

Contraindications

children under 1 year of age;
hypersensitivity to the components of the drug.

Use during pregnancy and breastfeeding

Use in children

Contraindicated for children under 1 year of age.

special instructions

Use with caution in case of arterial hypotension.

Impact on the ability to drive vehicles and operate machinery

No data.

Drug interactions

Kudesan can potentiate the effect of diltiazem, metoprolol, enalapril and nitrates, and also reduce the effect of warfarin.

Analogues of the drug Kudesan Q10

Structural analogues according to active substance:

Valeocor Q10;
Kudevita;
Kudesan for children;
Ubidecarenon.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps and look at the available analogues for the therapeutic effect.

Some chronic diseases or monotonous poor nutrition child become the cause of a decrease in the concentration of the substance coenzyme Q10 in his body, necessary for proper operation the whole body. Among the first to experience shortages important element the heart and blood vessels react, and after them other internal organs begin to suffer. For example, an unstable heart rhythm in a baby causes shortness of breath. In this case, in addition to the required medications, pediatrician may prescribe the drug Kudesan to a young patient. This is the remedy stimulates the work of the heart muscle, improves breathing and restores impaired metabolic processes.

Kudesan is a dietary supplement containing coenzyme Q10 and vitamin E.

Composition and effect of the drug

The main component is ubidecarenone (ubiquinone) or coenzyme Q10. This molecule is part of an enzyme protein that serves as a catalyst for biochemical intercellular processes. Ubiquinone is involved in all chemical reactions reproduction, transportation and exchange of energy between the cells of the body.

Due to its properties, coenzyme Q10 has an important effect on the functioning of the entire body:

improves blood flow in the heart vascular system, restores the heart rate of the heart muscle and stabilizes the heart rhythm;
shortens the recovery period of damaged organ tissues and creates good cell protection from free radicals;
restores metabolism;
strengthens the immune system.

The medicine will help strengthen the immune system.

To enhance the antioxidant effect of coenzyme Q10, vitamin E is added to the preparation. Detailed composition Kudesana is indicated in the instructions.

Download instructions for use in pdf format →

Application area

Pediatricians prescribe Kudesan to children in combination with other medications when making the following diagnoses:

diseases of the heart and blood vessels (arrhythmia, heart failure, dysfunction of the cardiac ventricles, etc.);

The drug is intended for complex therapy of diseases of the cardiovascular system.

chronic kidney and digestive diseases;
damage to the central nervous system;
muscular dystrophy;
the presence of benign tumors.

The drug is also often used for:

preparation little patient before and after heart surgery;
rehabilitation after severe course illness;

Kudesan can be given to children for preventive purposes as prescribed by a specialist, but with caution if the child has persistently low blood pressure.

Manufacturer, release form and price

Kudesan is produced in Russia by two pharmaceutical companies: Vneshtorg Pharma LLC and Akvion CJSC, and registration certificate The name is owned by Rusfik LLC.

The drug has two forms of release - drops and chewable tablets.

Drops 3%

The drops are a yellow-orange solution, which is poured into dropper bottles of 15, 20, 25, 50, 60 and 100 ml. Each bottle is packaged in an individual box along with instructions for use.

Drops are an indispensable option for parents whose children cannot take pills or simply do not want to do so.

At the pharmacy you can buy 2 types of Kudesan drops, which differ in the different amounts of active substance in the main composition.

Chewable tablets

They are placed in 10, 12, 15 pieces per contour cell, of which there can be 1, 2, 3 or 4 in one box.

Chewable tablets have a pleasant creamy taste.

Kudesan in tablet form is available in three options, differing in the concentration of coenzyme Q10 and the presence of additional components in their composition.

Dosage and administration

The drug is needed Give to children only once a day in the morning during breakfast. If the pediatrician has prescribed Kudesan drops to the child, then the required amount of solution is first diluted in a liquid (water, juice) at room temperature and given to the child to drink during meals.

Just dilute the drops with water or juice.

The dosage depends on the age of the small patient and on the purpose for which the medicine was prescribed by the doctor: how prophylactic or as part of complex therapy.

Kudesan apply for 2-3 months. The second course of therapy is determined by the attending physician.

Contraindications and side effects

The drug should not be given to children with:

exacerbation of chronic kidney and gastrointestinal diseases;
individual intolerance to the drug.

In rare cases, young patients may experience the following symptoms after taking the drug:

nausea;

Side effect is nausea.

diarrhea;
allergy.

If your child experiences side effects, show him or her to the pediatrician.

Compatibility with other drugs

Do not give your child Kudesan and medications at the same time:

reducing cholesterol and high blood pressure;
antiarrhythmic;
vasodilators;
blood thinners (for example, Warfarin);
antidepressants.

This combination of drugs reduces the amount of coenzyme Q10 in the baby’s blood and impairs the functioning of his cardiovascular system.

Analogues

Kudesan has two Russian analogues, but they can only be taken from adolescence:

Kudevita (30 mg tablets). Prescribed to children from 12 years of age. average price- 128 rubles. Manufacturer - FSUE "TsNKB".
Coenzyme Q10 Forte with vitamin E (tablets 500 mg). Approved for treatment when grown uptkov from 14years. average cost- 320 rubles. Manufacturer: Realcaps.

If a child has an intolerance to the components of Kudesan, and you could not find an analogue composition suitable for your child’s age, then you can buy drugs with a similar effect at the pharmacy:

Elkar. Active substance- levocarnitine. Prescribed to children with3 year oldage. Treatment of children under 3 years of age should be carried out strictly under the supervision of a pediatrician. The average price for 1 bottle of solution (50 ml) is 440 rubles. Manufacturer: PIK-Pharma PRO LLC, Russia.

Elkar is an analogue of Kudesan.

Panangin. Used to treat children only in exceptional cases under the supervision of a doctor. The main substances are potassium and magnesium aspartate. The average cost for 1 package (5 ampoules) is 140 rubles. Manufacturer: Gedeon Richter, Hungary.

Reviews

Anastasia from Moscow shares:

“When my girl was one month old, she had heart surgery. After being discharged from the hospital, we were prescribed a whole bunch of heart medications and Kudesan. I dilute two or three drops of the drug in the mixture and give it to the child once during the morning feeding. The treatment regimen is as follows: 1 month - Kudesan, the second - Elkar, and then - Kudesan again. My daughter recovered very quickly, our heart is growing. Doctors did not notice any developmental delays in her. And one more nice moment I want to note. My eldest son goes to kindergarten and has already been sick several times colds, and the baby never got infected from him.”

Polina from Naberezhnye Chelny says:

“My son is 6 years old. We underwent an examination before school and gave the child a cardiogram, the result of which was not very good: an irregular heart rhythm. Our pediatrician referred us to a cardiologist. The doctor examined his son, said that so far he didn’t see anything wrong, and prescribed treatment. First we took vitamin B6 for 2 months, and then Kudesan - also for 2 months. A repeat cardiogram showed that everything is fine with my child.”

The medicine replenishes energy levels, which helps children remain full of energy when they come home from school.

Cardiologist Yuri Kirillovich from Syktyvkar advises:

“The drug has long been good result used to treat children under one year of age and even infants. In the extensive list cardiovascular diseases almost 30% are due to pathologies associated with heart rhythm disturbances. The fact is that with diseases of the heart muscle, the antioxidant protection of blood cells from free radicals is reduced, which leads to a dangerous malfunction of the heart. Therefore, as part of complex therapy for arrhythmia, I always prescribe Kudesan, which contains the natural antioxidant ubiquinone. Thanks to its action, children pass faster rehabilitation period after acute course disease, and the number of relapses is significantly reduced."

Give the drug to infants only under the supervision of the attending physician.

Bottom line

A constant lack of just one microelement - ubidecarenone in a child's body can lead to a serious deterioration in his health. And timely replenishment the required substance will protect your baby from unpleasant consequences. The drug Kudesan copes well with several tasks at once:

eliminates coenzyme Q10 deficiency;
serves as a good prevention of the development of chronic diseases;
reduces the manifestations of existing diseases;
restores metabolic processes;
improves adaptation to increased physical activity;
helps rapid recovery after operations;
strengthens the immune system.

Inga Fedorova

1 ml drops contain ubidecarenone 30 mg, as well as additional substances: ascorbyl palmitate, tocopherol acetate, citric acid, cremophor, sodium benzoate, water.

Children's drug in 1 tablet includes 7.5 mg ubidecarenone. As additional substances: dextrose monohydrate, silicon dioxide, povidone, magnesium stearate, talc, creamy flavor.

Tablets for adults Kudesan Forte consist of 30 mg ubiquinone and 4.5 mg tocopherol acetate. Additional substances: colidon, aerosil, calcium stearate, primelose, microcrystalline cellulose.

Kudesan Forte in the form of a 1 ml solution contains 60 mg of coenzyme Q10 and 6.8 mg of tocopherol.

Kudesan with magnesium and potassium in 1 tablet includes: 7.5 mg of ubiquinone, potassium - 97 mg (in the form of potassium aspartate 450 mg), magnesium - 16 mg (in the form of magnesium aspartate 250 mg).

What is the difference between Kudesan and Kudesan Forte?

Kudesan Forte per 1 ml contains twice as much ubidecarenone and additionally it includes tocopherol acetate.

Release form

Kudesan and Kudesan Forte drops for oral administration in 20 ml bottles.
Chewable tablets for children in contour packages of 30 pcs.
Kudesan Forte tablets, 20 pcs. packaged.
Kudesan with magnesium and potassium 40 pcs. packaged.

pharmachologic effect

Normalizes metabolic processes in the myocardium and reduces tissue hypoxia. By its nature it is a coenzyme similar to vitamins. Increases ATP synthesis and takes an active part in cellular respiration reactions.

It has antioxidant effect– protects cell membranes from damage by lipid peroxidation products.

Able to reduce the area of ischemia in the myocardium, increases exercise tolerance. Sufficient education coenzyme Q10 in the body occurs only in young people under 20 years of age. After this age the level ubiquinone starts to decline. Also, a decrease in content can be observed even in children with illnesses.

Possesses cardioprotective And cardiotonic effect, has immunostimulating And adaptogenic Effect. Restores performance, increases the body's adaptive capabilities when increased loads and stress, increases resistance to hypoxia.

Pharmacodynamics and pharmacokinetics

No data.

Indications for use

The drug is used as part of complex treatment and for prevention.

In adults:

cardiomyopathy;
heart failure;
arrhythmias;
myocardial infarction during the recovery period;
cardiac ischemia;
arterial hypertension;
preparation for aortic surgery - coronary bypass surgery and other surgical interventions on the heart.

Instructions for use of Kudesan for children determine the possibility of taking it for the following diseases:

heart diseases ( cardiomyopathy, heart failure, arrhythmias);
preparation for operations for congenital and acquired defects;
kidney diseases (metabolic nephropathy, chronic pyelonephritis);
diseases of the nervous system ( autonomic-vascular dysfunction, neurodegenerative diseases hereditary nature, muscular dystrophies, congenital myopathies);
chronic gastroduodenitis;
recovery period after operations and serious illnesses;
asthenic syndrome.

In children and adults, the drug is used to increase adaptation at elevated physical activity and to make up for the lack coenzyme Q10 in organism.

Contraindications

individual intolerance;
children under 1 year old.

At reduced blood pressure use carefully.

Side effects

May rarely be observed nausea And diarrhea. Possible allergic reactions.

Instructions for use of Kudesan Q10 (Method and dosage)

The drug in the form of a solution is dissolved in a small amount of liquid and taken with meals in the morning 1 time per day.

For prevention, the medicine is taken:

adults and children over 12 years old, 12–24 drops;
children 7-12 years old 8 - 12 drops;
children 3 - 7 years old are prescribed 4-8 drops;
children from 1 year to 3 years - 2-4 drops.

The following dosages are used in the treatment of diseases:

adults and children over 12 years old take up to 60 drops per day;
age 7 - 12 years – 20 drops;
at the age of 3-7 years, up to 16 drops per day;
Children from 1 year to 3 years are prescribed up to 10 drops.

The duration of treatment is about 2-3 months. Repeated courses of treatment are possible on the recommendation of a doctor.

At coronary heart disease The medicine is prescribed three times a day, 30–45 mg.

To increase the tolerance of increased physical activity in athletes, a dose of 90-150 mg/day is used in 2-3 doses.

The instructions for Kudesan Forte drops for children over 14 years of age and adults recommend prescribing 5 drops 1 time per day with meals, with increased physical activity - 10 drops. 1-2 times a day during meals.

Forte tablets are dosed in 1 tablet. 1 r/d.

Kudesan with magnesium and potassium take 2 tablets. 2 times a day The course of treatment is 1 month.

Overdose

No cases were observed.

Interaction

Reception together with statins or fibrates(lipid-lowering drugs), beta-blockers ( metoprolol, atenolol, propranolol), tricyclic antidepressants leads to a decrease in the level ubidecarenone in blood.

Action enalapril, metoprolol, nitrates, diltiazem may intensify ubiquinone.

Coenzyme Q10 capable of weakening the effect warfarin.

Terms of sale

Kudesan in solution, Kudesan for children - according to prescription.

Kudesan Forte, Kudesan with magnesium and potassium - without a prescription.

Storage conditions

Maintain the temperature between 15° and 25°C, in a dark, dry place away from children.

Best before date

Analogues of Kudesan Level 4 ATX code matches:

Coenzyme Q10 Doppelhertz Active
Coenzyme Q10 Evalar

The price of analogues is from 210 rubles. up to 400 rub. for 30 tablets (capsules).

Contraindicated for children under 1 year of age.

During pregnancy and lactation

Since there is no clinical experience with its use, it is not recommended.

Kudesan for children is biologically active additive, which contains coenzyme Q10, as well as the substance tocopherol acetate. With the help of this remedy, the function of the heart apparatus is improved, the functions of organs are improved respiratory system, metabolic processes in the body are restored.

Main active ingredient The drug contains ubidecarenone (ubiquinone) or coenzyme Q10. This is a molecular component that stimulates biochemical intercellular reactions. This substance takes part in chemical processes metabolism at the cellular level.

With its help, the following effects occur on internal organs and systems:

Improving blood flow in the cardiac apparatus and in the vascular system, restoring heart rate, stabilizing heart rate;
Reducing the duration of tissue repair during internal organs, Creation reliable protection cell membranes from harmful effects free radicals;
Restoration of metabolic processes;
Increasing the body's endurance under increased loads;
Strengthening the natural resistance functions of the body.

The instructions for use indicate that the main forms of release are Kudesan drops and Kudesan chewable tablets for children. Such a form as syrup does not currently exist.

Chewable tablets have a pleasant creamy taste. Pharmacy chains have three options:

Kudesan with potassium and magnesium;
Kudesan for children;
Kudesan for adults.

Combining with others medications, Kudesan is very effective.

Indications

This medicine is prescribed to children as part of complex therapy for the following diseases:

Development of cardiomyopathies of various origins;
The presence of chronic heart failure;
Development of different forms;
Migraine-like conditions, genetic disorders in the function of the central nervous system (encephalopathy, tuberous form);
Development of chronic gastroduodenitis;
Myopathy, metabolic disorders;
, chronic nature.

Indications for use also include acute shortage coenzyme, disturbances during the adaptation period with increased physical activity in people who engage in heavy sports or physical work, in preparation for surgical intervention on the heart. Only a doctor can prescribe such a remedy for children, taking into account his condition, the severity of symptoms and the nature of the disease.

Instructions

The dosage of the drug is as follows: babies are allowed to give Kudesan drops only once a day. Before taking, you should dilute the drops in water or juice. Drink during the main meal.

All doses are determined by the return category of the child and the purpose for which the drug is prescribed:

Children from one to three years old are given 2-4 drops;
From 3 to 7 years old, give 4-8 drops;
From 7 to 12 years – 8-10 drops;
Adolescents over 12 years of age are given up to 24 drops once a day.

The duration of the course of therapy is at least two months. Then take a short break. Repeat course prescribed by the doctor after preliminary examination and consultations.

Contraindications

It is not allowed to give this medicine to children if there is an exacerbation chronic pathologies urinary system and organs digestive system, and also if there is individual intolerance active component drug.

Interaction Basics

Reduce concentration bad cholesterol in blood fluid;
Reduce blood pressure levels;
Drugs that are intended to combat;
Medicines that dilate the lumen of blood vessels;
Means for reducing the viscosity of blood fluid;
Antidepressants and muscle relaxants.