What are the dangers of an overdose of Glycine for health - harm and side effects. Glycine

Glycine is a drug from the psychoanaleptic group that improves brain metabolism.

Release form and composition

The dosage form of Glycine is sublingual tablets.

The active substance of the drug is microencapsulated glycine. Its concentration in one tablet is 100 mg.

The auxiliary components of the drug are magnesium stearate and water-soluble methylcellulose.

Glycine is sold in blister packs of 50 tablets.

Indications for use

According to the instructions, glycine, the active ingredient of the drug, is a metabolic regulator that has alpha1-adrenergic blocking, antitoxic and antioxidant effects, and also has glycine and GABAergic properties and regulates the activity of glutamate receptors. Due to the described properties, Glycine:

Improves mood;
Increases mental performance;
Reduces conflict and aggressiveness;
Improves psycho-emotional state;
Increases social adaptation;
Facilitates falling asleep, normalizes sleep;
Reduces vegetative-vascular disorders (including during menopause);
Reduces the toxic effect of alcohol and other drugs that depress the central nervous system;
Reduces the severity of brain disorders in TBI and ischemic stroke.

In accordance with the instructions, it is advisable to use Glycine for:

Stressful situations, including psycho-emotional stress (including conflict situations, during exam periods, etc.);
Decreased mental performance;
Organic and functional diseases nervous system accompanied by emotional instability, increased excitability, sleep disturbances, decreased mental capacity: with neuroses, consequences of traumatic brain injury and neuroinfection, neurosis-like conditions, vegetative-vascular dystonia, different forms encephalopathy (including the perinatal form and damage caused by alcohol);
Deviant forms of behavior in children and adolescents;
Ischemic stroke.

Contraindications

The only contraindication to the use of Glycine, according to the instructions, is increased sensitivity to its active or any auxiliary component.

Directions for use and dosage

Glycine is intended for sublingual use. If necessary, the tablet can be crushed into powder and applied buccally (i.e. by placing between upper lip and gum until completely dissolved).

For children, adolescents and adults with temporary emotional difficulties (including decreased attention, memory and/or mental performance), as well as with psycho-emotional stress, deviant forms of behavior, mental retardation, the medicine is usually prescribed 1 tablet two or three times a day. Treatment can last from 14 to 30 days.

For organic and functional lesions of the nervous system, which are accompanied by sleep disturbances, emotional lability, increased excitability, Glycine is prescribed:

Children under 3 years old – 1/2 tablet 2-3 times a day for 7-14 days, then 1 whole tablet for another 7-10 days. Daily dose fluctuates between 100-150 mg, the maximum permissible course dose is 2600 mg;
Children over 3 years old and adult patients – 1 tablet 2-3 times a day. The course of treatment is 7-14 days, in some cases the duration is increased to 1 month. If necessary, with a 30-day break, carry out repeat course therapy.

For sleep disorders, Glycine should be taken before bedtime (no more than 20 minutes) 1/2-1 tablet, depending on age.

For ischemic cerebral stroke, the drug is prescribed within the first 3-6 hours after the attack. The daily dose of Glycine can reach 1000 mg. The medicine should be given to the patient buccally or sublingually with 1 tsp. water. IN high doses The drug is taken for 1-5 days (as prescribed by a doctor), then for 30 days - 1-2 tablets three times a day.

As a means of reducing psycho-emotional stress and increasing mental performance during the period of remission in encephalopathy, organic lesions peripheral and central nervous systems, Glycine is used in narcology. Prescribe the drug 1 tablet two or three times a day. The standard course lasts from 14 to 30 days. As necessary, courses are repeated up to 6 times a year.

Side effects

According to the instructions and reviews from doctors, the use of Glycine is generally well tolerated. In rare cases, mainly with hypersensitivity to components, there are allergic reactions.

special instructions

At simultaneous use Glycine reduces the severity of side effects of antidepressants, anxiolytics, as well as anticonvulsants, hypnotics and antipsychotic drugs.

Analogues

Synonyms of Glycine, i.e. drugs with the same active ingredient are: Glycine forte, Glycine Ozone, Glycine-MHFP, Glycine-Bio, Glycine-Bio Pharmaplant, Glycine-Canon.

The following drugs also belong to the same pharmacological subgroup (“Psychostimulants and nootropics”) and have a similar mechanism of action: Amylonosar, Acefen, Bravinton, Vero-Vinpocetine, Vinpotropil, Vinpocetine, Vincetine, Ginkgo Biloba, Ginkum, Gopantam, Demanol, Idebenone, Cavinton , Calcium hopanthenate, Carnicetin, Cogitum, Combitropil, Cortexin, Lucetam, Memotropil, Minisem, Neuromet, Noben, NooKam, Nooclerin, Noopept, Nootropil, Omaron, Pantogam, Pantocalcin, Picamilon, Picanoil, Pikogam, Piracesin, Piracetam, Pyriditol, Semax, Telektol, Phezam, Ceraxon, Cerebrolysate, Cerebrolysin, Encephabol, Escotropil, etc.

Glycine is used in the composition complex therapy to normalize metabolic processes in the brain, the drug also has calming properties, stimulates mental activity, and improves memory. In fact, this medicinal substance is an amino acid that is part of the tissues of the human body, therefore it is considered harmless, and side effects after taking it, they usually do not occur. However, in some cases an allergy to glycine develops, which occurs with all characteristic features pathological reactions to medications, such as shortness of breath, rhinitis, lacrimation, skin rashes, etc. Experts explain this by the body’s increased sensitivity to glycine and its additional components, caused by a hereditary predisposition to allergies to medications and other irritants, for example, pollen, on food products or on pet hair.

Pharmacological properties and uses of glycine

Glycine or aminoacetic acid normalizes sleep, relieves psycho-emotional stress, and stabilizes brain function. Healing effect on the body due to the formation of special compounds that can remove toxic substances, due to which glycine is used to treat alcoholism, and it also has a stimulating effect on immune system. Glycine is an inhibitory neurotransmitter, that is, it is capable of enhancing inhibition processes that, when in good condition the body must prevail over the processes of excitation. This drug improves metabolic processes in the pituitary gland, blocks the production of stress hormones, which leads to a general antidepressant effect on the body.

Effects after taking glycine:

The person becomes less aggressive and less conflicted.
Mood improves, irritability goes away.
Insomnia disappears.
Neutralization occurs toxic effects ethyl alcohol on the central nervous system.

As a result of glycine therapy in humans, the level of social adaptation, the manifestations of disorders caused by strokes, traumatic brain injuries, neuroinfections and vegetative-vascular dystonia, the psycho-emotional background is normalized. Glycine enhances metabolism, due to which ethyl alcohol and alcohol breakdown products, for example, acetaldehyde, which causes hangover syndrome. When connecting the considered medicinal substance with acetaldehyde, acetylglycine is formed, which is necessary for the synthesis of enzymes, proteins and hormones.

Prescribing glycine is advisable for the following conditions:

Low intellectual and physical performance.
Increased excitability in children, hyperactivity.
Deviant behavior in adolescents.
Muscle tone.
Neuroses.
Stress and depression.
Vegetovascular dystonia.
Hypoxia.
Sleep disorders.
Damage to the central nervous system in infants.
Recovery period after traumatic brain injury, infectious lesions.
Included complex treatment alcoholism.
Ischemic stroke.
Epilepsy.

Glycine is prescribed with caution to patients whose activities require a high concentration of attention (drivers, dispatchers, etc.)

Causes of allergies and risk groups

Despite the simple composition of the drug glycine and the presence of its main active ingredient in the tissues of the human body, uncharacteristic reactions from the immune system still occur when taking it. So could there still be an allergy to this? safe remedy How's glycine? In fact, this is possible, although in very rare cases. Allergies are associated with several main reasons:

Hypersensitivity reactions to the drug usually occur in adults. But can a child be allergic to glycine? Undoubtedly, it can, since in children the immune system is at the stage of development, so it often reacts to various substances, as to allergens, for example, to medications, food products, etc. Usually, pathological reactions occur after the second dose of glycine, since in the interval between the first and second doses of the medicine the production of antibodies begins to occur. The following conditions are risk factors in which allergies are most likely to develop:

Long and uncontrolled treatment with glycine.
Availability of food or drug allergies from close relatives or from the patient himself.
Concomitant diseases, for example, bronchial asthma.
Worm infestations.
Fungal infections of the body.
Dysbacteriosis.

If you are allergic to glycine infant, then this can be attributed to the fact that the nursing mother does not comply special diet recommended for breastfeeding, or she takes it at the same time similar drug, which ultimately leads to an overdose. Other reasons are poor nutrition mothers during pregnancy, smoking, various infections. There are cases in which children are diagnosed with a congenital disorder of glycine metabolism in the body, or hyperglycinomia, the symptoms of which may go away on their own in the second or third month of life. Signs of this pathology include low muscle tone, cramps, and vomiting. The use of glycine in such children is very dangerous.

Allergic reactions to glycine usually cause symptoms characteristic of all other types of drug intolerance. A person develops a rash on the body, accompanied by intense itching, hyperemia, dryness, swelling and peeling of the skin. An unreasonable runny nose occurs, the mucous membranes of the eyes, nose and oral cavity, breathing becomes difficult due to shortness of breath and pathological decrease blood pressure a person may feel weak and dizzy. In particular severe cases, which is rare, an allergy to glycine causes the development of angioedema or anaphylactic shock. Reaction to this drug occurs a few hours after taking it, a day later or a few days later.

As for glycine overdose, it does not occur immediately. With continuous use of tablets, a cumulative effect is observed, and this usually has a beneficial effect on the body, but subject to the correct dosage. Exceeding recommended doses leads to the body becoming accustomed to high content glycine, which causes the occurrence of irreversible processes in neurons. An overdose of a drug provokes the following symptoms:

Nausea and vomiting.
Diarrhea.
Dizziness.
Pain in the head.
Dermatitis.
Apathy.
Problems concentrating.
Decreased mental activity.
Weakness and lethargy.
Reduced blood pressure.
Night cramps.

When using glycine for several weeks and large doses epilepsy may develop, particularly in children and the elderly.

Features of the course in children

Very dangerous, because with a tendency to pathological reactions to this substance in young patients there may be signs of central nervous system disorder, seizures, excessive sleepiness, loss of consciousness, epileptic seizures. It is also likely that a serious strain on the child's kidneys will occur, especially if the cause of the allergic reaction is an overdose of glycine. This usually happens when parents independently decide on the need for treatment with this drug, without taking into account the possibility of such consequences.

Treatment

After diagnostic procedures and the diagnosis is confirmed, the doctor prescribes treatment for glycine allergy. Special therapy is necessary in cases where pathological symptoms do not disappear even after complete discontinuation of the drug. There are several effective methods treatment of allergies caused by various irritants, including medications. We are talking about methods such as:

Elimination treatment.
Pharmacological.
Therapeutic diet.
Ethnoscience.

Elimination

The term elimination means the elimination of irritants from the life of a person suffering from allergic reactions to certain substances. Elimination treatment drug allergies implies the complete exclusion of a drug that is a source of pathology, as well as drugs with a similar composition, including complex drugs containing an allergen substance. It is equally important to protect the patient from other irritants that can worsen health, for example, sources of house dust, food, causing allergies, pet hair, plant pollen, etc.

Pharmacological

Drug therapy for glycine allergy includes taking antihistamines, as well as means for the treatment of local manifestations of reactions, ointments, creams. Doctors prefer allergy medications with a minimum number of side effects, for example, Cetirizine, Rhinital, Erius, Desloratadine, Telfast, Zyrtec. If taking these medications does not bring relief to the patient, then hormonal agents in the form of tablets or injection solutions. As for skin, then the use of ointments such as Fenistil, Desitin, Panthenol, Bepanten is recommended. In cases where the cause of an allergy to glycine is an overdose, the patient’s stomach is washed or sorbents are prescribed - White coal, Enterosgel et al.

Therapeutic diet

A hypoallergenic diet will help reduce the symptoms of the pathology, so following it is important for any type of the disease in question, especially during exacerbations. Products with increased degree allergenicity. These include:

Seasonings and spices.
Smoked meats.
Nuts.
Mushrooms.
Sauces, mayonnaise, ketchup.
Semi-finished products.
Sweets.
Chocolate.
Citruses and exotic fruits.
Milk products.
Eggs.
Strawberry.
Coffee.

Very dangerous for allergy sufferers nutritional supplements, flavorings, dyes, preservatives, flavor enhancers, so you should avoid consuming products with such substances. Preference should be given to gray bread, lean meat, fermented milk products. Very helpful pearl barley, corn, buckwheat and millet. It is recommended to eat colored and regular vegetables and fruits. white cabbage, fresh herbs, apples, cherries, pears. Don't forget about drinking plenty of fluids, because the use large quantity clean water will help remove it from the body faster harmful substances. Compliance with the diet is important at least during the period of treatment of an allergy to the drug, and after withdrawal pathological symptoms the introduction of non-recommended foods into the diet should be gradual.

ethnoscience

As an auxiliary remedy you can use recipes from traditional medicine, suggesting the use medicinal plants, both internally and for treating skin lesions. However, caution should be exercised here, since some herbs themselves can cause allergies. To relieve allergy symptoms, sea buckthorn or olive oil, make a compress from a decoction of oak bark, chamomile or sage. For destruction pathogenic bacteria To heal wounds and eliminate itching and redness, it is recommended to use a rich decoction of pomegranate peels, which can be used to wash the skin or make compresses. To eliminate general signs allergies, tissue swelling, difficulty breathing, etc., use the following recipes:

Infuse a small handful of Lespedeza capitata in one liter for several hours cold water, take the resulting composition orally several times a day.
Drink an infusion of black alder leaves or crushed bark.
Pour boiling water over chamomile flowers, cumin seeds, red clover, cool, then take orally during the day when thirst arises.

Paying attention to your health will help you avoid many health consequences. You should not take glycine unless indicated or recommended by a doctor, especially if you are prone to allergic reactions to medications or other substances.

Update: October 2018

Glycine is one of the most popular metabolic drugs prescribed to improve mental and physical abilities, as well as as a sedative and sleeping pills in pediatrics and for adult patients.

The effect can be both calming and activating in relation to the central nervous system and varies depending on the time of taking the drug during the day - this is stated in the instructions for using Glycine.

However, you should immediately focus on the fact that all nootropic drugs, without exception, work only in pathologically changed tissues, improving directly metabolic processes in brain cells during disorders, but have no effect on healthy tissue . That is, their use for stimulation mental activity children, adults (as is often recommended) - if not completely useless, then ineffective (see).

Pharmaceutical group: A drug to improve brain metabolism. By ATC classification belongs to the group of nootropics and psychostimulants.

Composition of the drug, release form, price

Active ingredient of the drug– glycine. 1 tablet of 100 mg contains 100 mg of glycine. Excipients 100 mg tablets are: 1 mg magnesium stearate, 1 mg water-soluble methylcellulose.
Release form: sublingual tablets with a sweetish taste, white with marble inclusions, flat-cylindrical with a chamfer shape.
In blister packs of 50 sublingual tablets, in a cardboard box.
Glycine tablets are also available in dosages of 150, 400 and 500 mg.

Price: Glycine No. 50, 100 mg: 29-36 rub.

pharmachologic effect

Glycine is the simplest aminoacetic acid. It is part of protein molecules and biologically active compounds. Glycine is the basis for the synthesis of porphyrins, from which hemoglobin and myoglobin are subsequently synthesized, as well as purine bases. It regulates metabolic processes, activates and normalizes defensive reactions inhibition in the central nervous system, eliminates psycho-emotional stress, increases cognitive function and mental capacity. It has alpha1-adrenergic blocking, glycine- and GABA-ergic, antioxidant and antitoxic effects. Glycine regulates glutamate receptors, thereby achieving the following actions drug:

reducing conflict and aggressiveness;
increasing the level of social adaptation;
improvement and stabilization of mood;
acceleration of falling asleep and improvement of sleep quality (see);
reduction in severity, including those associated with menopause (see);
reducing the severity of central nervous system disorders due to stroke and TBI;
decrease toxic effect ethyl alcohol and medicines, inhibiting the activity of the central nervous system.

Pharmacokinetics— the drug quickly penetrates into biological fluids and tissues of the body, including brain matter. Without accumulating in tissues, it is completely metabolized to water and carbon dioxide.

Indications for use

The instructions for use of glycine indicate:

Decreased performance, mental and physical;
Stress and associated psycho-emotional tension;
Overstrain of the central nervous system during periods of increased mental stress(exams, etc.);
Deviant, contradictory accepted standards, behavior in adolescents and children;
Perinatal damage to the central nervous system in infants;
Ischemic stroke;
Organic and functional diseases nervous system, accompanied by emotional instability, high excitability, decreased mental performance and sleep disturbance:
- neurosis-like conditions and neuroses
- vegetative-vascular dystonia
- recovery period after TBI (traumatic brain injury) and neuroinfections
- perinatal and other types of encephalopathies, including alcoholic and drug-induced.

This is written in the instructions for glycine, but the first 4 points should not be taken seriously. As a result of numerous studies, the effectiveness of nootropics (including glycine) for improving mental and physical performance and memory has not been proven. Only 1 small study of glycine has shown that it has little effectiveness in CNS disorders, and not in severe cases. For example, in the USA glycine is not used in these cases (the first 4 points); it is only occasionally used in psychiatric clinics for the treatment of a number of patients.

Contraindications

Glycine is not prescribed if there are individual hypersensitivity reactions to the drug and its components.

Glycine for pregnant and breastfeeding women

It can be used to treat these groups of women, but strictly as prescribed by a doctor.

Dosage

Glycine tablets are intended for sublingual resorption. You can dissolve the drug behind the cheek, or use a pre-crushed tablet in powder form.

Nervous system lesions related to organic and functional changes and occurring with increased excitability, changes in the emotional background, sleep disturbance: adults, 1 tablet (100 mg) of glycine twice or thrice a day for 7-14 days. The course of treatment can be extended up to 30 days. Repeated course use is possible 30 days after completion of the previous course.
Sleep disorders: 0.5-1 tablet per 20 minutes of sleep.
Ischemic cerebral stroke: 1000 mg of the drug buccal or sublingual with 1 tsp. water during the first 3-6 hours; 1000 mg per day for the next 1-5 days; then - 1-2 tablets of glycine three times a day for another 30 days.
Encephalopathies, consequences of organic damage to the nervous system (central and peripheral): 1 glycine tablet twice or thrice a day for 14-30 days. Courses are repeated 4-6 times throughout the year.

Instructions for use of glycine for children

The drug has sweet taste, so children usually take the pills with pleasure. If tablets cannot be absorbed (newborns, early childhood) it is permissible to grind the required amount of the drug into powder and dilute it in a teaspoon of water.

Children under three years old: 0.5 tab. (50 mg) of glycine taken twice or thrice a day for 7-14 days, then 50 mg once a day for 7-10 days. The daily dose for children under 3 years of age is 100-150 mg of glycine, and the course dose is no more than 2000-2600 mg.
Children over 3 years old the drug is prescribed in an adult dosage: 1 tablet (100 mg) twice or thrice a day for 1-2 weeks, with a maximum increase in the course to 4 weeks.

Side effects of glycine

It is possible to develop hypersensitivity reactions in the form of a rash.

Overdose

No cases of overdose have been described. Possible: low blood pressure, dizziness and nausea.

Drug interactions

At simultaneous administration with drugs from the groups of anxiolytics, antipsychotics, anticonvulsants, hypnotics and antidepressants, glycine reduces the severity of the side effects of the former.

special instructions

Prescribed with caution to persons managing vehicles and those involved in working with precision mechanisms.

Glycine analogues

Nootropics also include Piracetam (Nootropil, Piracetam, Lucetam), Noopept. Among herbal remedies We can highlight Ginkgo biloba (Bilobil, Memoplant, Ginkgo Biloba, Tanakan, Ginkum, Doppelherz ginkgo biloba with vitamins gr.B, Vitrum memory), which improves metabolic processes in neurons, as well as enhances the effect of nootropic drugs.

IN pharmacy points you can find Glycine: Glycine ozone, Glycine-Bio, Glycine Evalar, Glycine Forte, Glycine-Canon.

Vita glycine + vit. gr.B

100 pieces. 500 mg. 1100 rub.

Glycine Evalar

20 pcs. 50-80 rub.

Glycine Forte

50 pcs. 17 rub.

Glycine Bio

100 mg. 50 pcs. 30 rub

Doppelhertz glycine (+vit. gr B)

30 caps. 150 rub.

Glycine ozone

Glycine -Canon

From the point of view of pharmaceutical science, “Glycine” is a drug based on one of the amino acids - aminoacetic, which is also called aminoethane. Similar acids are produced by the human body with the help of the liver, however, if their quantity is insufficient, the situation can be corrected by taking the required substance.

Action of "Glycine"

The pharmaceutical effect is based on the fact that the amino acid it contains affects the functioning of one of the most important parts - the pituitary gland. As a result. Metabolic processes in the brain improve, which, in turn, leads to a general antidepressant effect on the body.

The doctor can prescribe the use of “Glycine” in the most various cases. For example, the group of common indications for its use includes a variety of stressful situations, which entail the emergence negative consequences such as insomnia, depressive state, irritability, decreased performance and others. Moreover, this drug can be prescribed both to children, for example, when they display aggressiveness or symptoms of antisocial behavior.

However, in addition to eliminating common symptoms, which to one degree or another are characteristic of almost everyone to modern man, "Glycine" can also be used as medicine as part of complex therapy in the treatment of more serious illnesses. Thus, it is used in the treatment of neuroses of various etiologies, as well as the consequences of neuroinfections, traumatic brain injuries and even strokes.

Side effects of Glycine

As with any drug, taking Glycine may cause some unpleasant consequences, commonly called side effects. However, due to the fact that the action of “Glycine” is based on the content of an amino acid in it, identical to that which is independently produced human body, the nature and intensity of these side effects can be called minimal.

Thus, the drug contains mention of only one possible side effect from its use - the occurrence of allergic reactions, which may result from individual intolerance to the main or auxiliary components included in its composition. Besides, additional effect when taking "Glycine" is that it reduces the intensity of the unpleasant side effects of other drugs that affect the nervous system.

– a drug with antidepressant and sedative effect, used to treat stress conditions and neurological diseases accompanied by sleep disturbances, decreased performance and increased excitability.

The drug can have both a calming and activating effect, which is due to the peculiarities of the effect of glycine on the body. This applies medicine to the group of psychostimulants and nootropics.

The description of the drug Glycine is not intended for prescribing treatment without the participation of a doctor.

Instructions for use:

Composition and release form

Glycine is produced in the form of flat-cylindrical tablets of white color with marbling elements. Sublingual tablets. The composition of the drug includes:

Glycine forte evalar

Dosage form – lozenges 600 mg (20 or 60 pieces per package).

Composition for 1 tablet weighing 600 mg:

glycine 250 mg;
vitamin B1 (thiamine) 2.5 mg;
vitamin B6 (pyridoxine) 3 mg;
vitamin B12 (cobalamin) 0.0045 mg;

pharmachologic effect

Glycine is a metabolic regulator, normalizes and activates protective inhibition processes in the central nervous system, reduces psycho-emotional stress, and increases mental performance.

Glycine has glycine- and GABA-ergic, alpha1-adrenergic blocking, antioxidant, and antitoxic effects; regulates glutamate (NMDA) receptors, due to which the drug is able to:

Patients who completed the course of treatment noted that they stopped having headaches and their memory abilities improved. From the sublingual area, medicine into as soon as possible absorbed into the bloodstream, distributed in tissues and biological fluids. During biotransformation, the amino acid decomposes to carbon dioxide and water. Glycine does not accumulate in the body.

Pharmacokinetics

Easily penetrates most biological fluids and body tissues, incl. into the brain; metabolized to water and carbon dioxide, glycine does not accumulate in tissues.

Indications for use of glycine

Glycine is a popular metabolic agent used to treat autonomic and other disorders. Indications for taking glycine include:

Functional and organic diseases nervous system, accompanied by increased excitability, emotional instability, decreased mental performance and sleep disturbance:

neuroses;
neurosis-like conditions;
vegetative-vascular dystonia;
consequences of neuroinfections and traumatic brain injury;
perinatal and other encephalopathies (including those of alcoholic origin);
ischemic stroke.

In addition, glycine is part of complex therapy at alcohol addiction . This is due to the fact that the amino acid helps reduce the desire to drink alcohol.

The use of amino acid is advisable during the off-season when changes in atmospheric pressure and temperature provoke autonomic disorders.

Glycine is recommended for people suffering from meteosensitivity, increased nervous excitability and insomnia. Amino acid dosages are selected by the attending physician on an individual basis. The dose of the substance depends on the type of disease and the severity of the pathological process.

A drug not addictive, it is possible to take glycine for a long time.

Use in sports

Use of the drug in sports nutrition helps you achieve your goals. This tool creates conditions for good rest and recovery between workouts. The drug is taken on the recommendation of a nutritionist or sports doctor. Official instructions does not prohibit the use of glycine in sports.

Glycine for children

Glycine for children is prescribed by a pediatrician, individually selecting the dosage, focusing on the child’s age and the severity of the pathological condition.

Glycine is also prescribed to healthy children in minimal quantities - 1 tablet per day (provided that the child is over 3 years old). It improves brain activity and the baby’s memory, increases academic performance and reduces aggressiveness in adolescence. The course of taking the drug is 2-4 weeks.

Average daily dosage the drug for children is as follows:

children under 3 years old - 1/2 tablet;
over 3 years – 1 tablet.

Glycine for babies

For children, the drug is prescribed for excessive excitability, restlessness and sleep disturbances. Of course, newborns are not able to absorb glycine on their own, so half the tablet needs to be crushed to a powder and divided into two doses. Before giving it to your child, dissolve the medicine in a spoon of water and drop it into the mouth. Glycine for infants is soaked for a period of no more than two weeks.

Contraindications

Individual hypersensitivity to the components of the drug.

Is it possible to drink glycine during pregnancy?

If an expectant mother or a nursing woman develops nervous disorders, then it is recommended to take the amino acid in a standard therapeutic dosage.

During pregnancy and lactation, the use of glycine needs to be agreed upon with your attending physician.

Directions for use and dosage

Glycine is applied sublingually or transbucally, 0.1 g (in tablets or in powder form after crushing the tablets). For healthy children, adolescents and adults, glycine is prescribed 1 tablet 2-3 times a day for 14-30 days for the following conditions:

psycho-emotional stress;
memory loss;
deterioration of attention;
decreased mental performance;
mental retardation;
deviant behavior.

For functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbance:

For sleep disorders Glycine is prescribed 20 minutes before bedtime or immediately before bedtime, 0.5-1 tablet (depending on age).

For ischemic cerebral stroke: during the first 3-6 hours of stroke development, 1 g is prescribed buccally or sublingually with one teaspoon of water, then for 1-5 days, 1 g per day, then for the next 30 days, 1-2 tablets 3 times a day.

In narcology glycine is used as a means of increasing mental performance and reducing psycho-emotional stress in cases of encephalopathy, organic lesions of the central and peripheral nervous system, 1 tablet 2-3 times a day for 14-30 days. If necessary, courses are repeated 4-6 times a year.

Sublingual and buccal administration

The pharmacological term “sublingual” is derived from two Latin words “sub” and “lingua”, meaning “under” and “tongue”, respectively. In other words, sublingual administration is placement medical supplies under the tongue. To do this, the tablet must be placed in the sublingual area and dissolved until it dissolves.

Transbuccal administration of drugs (lat. buccalis, buccal) is a pharmacological term meaning the administration of a certain drug by placing it between the upper lip and gum or in the oral cavity until completely absorbed. In this case, the medicine is sent into the blood circulation through the mucous membranes of the oral cavity.

Dosage of Glycine forte Evalar

Tablets are intended for oral administration, they should be kept in the mouth until completely absorbed.

do not prescribe pregnant, lactating women and children.

Side effect

Allergic reactions are possible.

Interaction with other drugs

Reduces the severity of side effects of the following drugs:

antipsychotics (neuroleptics);
anxiolytics;
antidepressants;
sleeping pills;
anticonvulsants.

Glycine and alcohol

Most medications should not be taken together with alcohol. However, glycine is also useful in this case. Thanks to the drug entering the body, metabolism accelerates and alcohol is removed from the blood faster, resulting in a person sobers up faster. Yes, and intoxication when using the drug occurs more slowly due to a decrease in negative impact alcohol on the body.

Besides, glycine is used for chronic alcoholism and when eliminating severe consequences binge drinking, but how aid. It is noted that the drug is able to remove poisons from the body formed under the influence of alcohol and reduce cravings for alcohol.

The drug is used and to eliminate a hangover. The condition improves after taking two tablets of the drug. A maximum of four such receptions are allowed per day. It is also recommended to take glycine every sixty minutes during a long feast to avoid a hangover the next day.

However glycine overdose When drinking alcohol, it aggravates the state of intoxication.

In excess doses the drug causes weak drug effect, and this increases intoxication. If the drug is taken incorrectly, the body increases Instructions for use: ammonia and acetic acid, which will have a negative effect on a person who is intoxicated.

Storage conditions

Keep dry dark place out of reach of children, at a temperature not exceeding 25C. Shelf life: 3 years. Do not use after the expiration date stated on the packaging.

Conditions for dispensing from pharmacies

Over the counter.

Special instructions for use

It is recommended to use the drug with caution in patients suffering from arterial hypotension . In this case, the doctor prescribes the drug in a reduced dose and constant monitoring of blood pressure is required during treatment. If upon observation arterial pressure decreased sharply, the drug must be stopped.

Glycine analogues

Analogues with others active ingredients, but with the same operating principle:

Mexidol;
Neurotropin;
Tryptophan;
Cebrilisin;
Elfunat;
Antifront;
Armadin;
Glutamic acid.

Glycine price

What foods are high in glycine?

There is a lot of glycine in gelatin, and accordingly in jelly, marmalade and jellied meat. Glycine in sufficient quantity found in protein foods:

beef;
liver;
bird;
fish;
cottage cheese;
eggs.

In addition, glycine is also found in products of plant origin:

buckwheat;
ginger;
oats;
nuts;
brown brown rice;
sunflower and pumpkin seeds.

Eating fruits such as apricots, bananas and kiwis is also helpful to replenish glycine stores.

It is important to note that when preparing dishes, the amount of glycine in foods changes. For example, when frying, baking and stewing, the amount of glycine increases by 5-25%. And when drying, salting, smoking it decreases by 10-25%.