Immunostimulants list of drugs. Natural immunostimulants – Eleutherococcus

Immunomodulators are called drugs that affect the immune system and change its functioning. Immunomodulators can be divided into 2 groups:
1. Immunostimulants – stimulate immune reactions, increase immunity.
2. Immunosuppressants – lower the immune system.

Thus, any immunostimulant is an immunomodulator, but not every immunomodulator is an immunostimulant.

In any case, it is more correct to use the term “immunomodulators”, because increasing immunity with the help of immunostimulants is not unlimited, but only to the level physiological norm.

What are immunomodulators - video

Use of immunomodulators

Immunomodulators are used mainly to increase the body's defenses in various diseases:

• chronic, indolent infections;
• allergic diseases;
• tumors;
• states of immunodeficiency.

But in some cases (with autoimmune diseases, when the immune system begins to work not against “external enemies”, but against own body), immunomodulators are used to reduce immunity.

The use of immunomodulators is based on the following principles:

• As part of complex treatment, in parallel with the prescription of antibiotics, antiviral, antifungal and other agents.
• Appointment from the first day of treatment.
• Under control immunological research blood.
• Separately, without other drugs, immunomodulators are used at the stage of rehabilitation and recovery after illness.

Treatment with immunomodulators is not quite the correct term. These drugs do not cure the disease - they only help the body overcome it. The effect of immunomodulators on the human body is not limited to the period of illness - it continues for a long time, for years.

Classification of immunomodulators

There are several classifications of immunomodulators. According to one of them, all these drugs are divided into three groups:
1. Endogenous(synthesized in the body itself). A representative of this group is interferon.
2. Exogenous(enter the body from the environment):

• bacterial: Bronchomunal, IRS-19, Ribomunil, Imudon;
• herbal: Immunal, "Echinacea liquidum", "Echinacea compositum SN", "Echinacea VILAR".

3. Synthetic drugs (representatives: Levamisole, Polyoxidonium, Glutoxim, Galavit, Poludan, etc.).

Another classification divides immunomodulators into generations, according to chronological order their creation:
I. First generation drugs (created in the 50s of the 20th century): BCG vaccine, Pyrogenal, Prodigiozan.
II. Second generation drugs (created in the 70s of the 20th century): Ribomunil, Bronchomunal, Broncho-Vaxom, Likopid, IRS-19.
III. III generation drugs (created in the 90s of the 20th century): this group includes the most modern immunomodulators - Kagocel, Polyoxidonium, Gepon, Myfortic, Immunomax, Cellsept, Sandimmune, Transfer Factor, etc. All these drugs, except Transfer Factor, have narrowly targeted use, and they can only be used as prescribed by a doctor.

Immunomodulators of plant origin

Plant immunomodulators have been used in folk medicine since ancient times - these are many of medicinal herbs included in old recipes. Exactly these, natural immunomodulators, have the most harmonious effect on our body.

Immunomodulator plants are divided into two groups. The first group includes licorice, white mistletoe, milky white iris, yellow egg capsule. These plants have complex composition, can not only stimulate, but also suppress the immune system. Therefore, treatment with them is possible only with careful selection of the dose, with immunological blood tests and under the supervision of a doctor.
The second group of plant immunomodulators is very extensive. These include:

• echinacea;
• ginseng;
• lemongrass;
• Aralia;
• Rhodiola rosea;
• Walnut;
• elecampane;
• cranberry;
• rose hip;
• Melissa;
• figs and many other plants.

They have a mild, slow, stimulating effect on the immune system, causing almost no side effects. Immunomodulators of this group can be recommended for self-medication.

It is prescribed for adults and children, but is contraindicated in case of an allergy to the drug itself, or in case of exacerbation of any allergic disease.

Dibazol

Dibazol is an outdated immunomodulatory drug. It promotes the production of interferon in the body, and is a means of lowering blood pressure. Therefore, Dibazol is prescribed mainly to hypertensive patients as an immunomodulator. Available in tablets and as a solution for injection.

Dekaris

Decaris is a drug whose main effect is anthelmintic. However, it also has immunomodulatory properties, and can be prescribed to adults and children as part of the complex treatment of herpes, acute respiratory viral infections, and warts. Available in tablets.

Transfer Factor

Transfer Factor is a drug considered the most powerful modern immunomodulator. Made from cow colostrum. This safe remedy, which has no contraindications or side effects. Age restrictions not in use either.

Transfer Factor is also used for preventive purposes.

Available in gelatin capsules for internal use.

Cordyceps

Cordyceps– immunomodulator plant origin. The raw material for its production is the cordyceps mushroom, which grows only in China, high in the mountains.

Cordyceps, as a true immunomodulator, increases reduced immunity, and reduces immunity when it is excessively increased. Capable of eliminating even genetic disorders immunity.

The drug has not only an immunomodulatory effect on the human body. It regulates the functioning of all organs and systems, slows down the aging of the body.

Cordyceps – drug fast action. Already in the oral cavity its absorption begins, and maximum effect appears just a few hours after ingestion.

Contraindications to the use of Cordyceps are epilepsy and breastfeeding. Prescribed with caution to pregnant women and children under five years of age.

In Russia, Cordyceps is considered not a medicine, but a biological one. active additive(dietary supplement), produced by the famous Chinese corporation Tianshi. Available in gelatin capsules.

Forms of release of immunomodulators

Immunomodulatory drugs are available in various forms dosage forms: in tablets, drops, capsules, suppositories, injection solutions.

Manufacturers are trying to give modern immunomodulators a form that is convenient for use. For example, Gepon is available in the form of a sterile powder contained in bottles. This provides a wide choice of methods of administering the drug: externally, orally, sublingually, in an enema, by instillation into the nose or by irrigation.

Modern immunostimulating drugs are classified according to their origin into the following groups:

• Herbal remedies– extracts or tinctures of Echinacea, Eleutherococcus, Schisandra, Immunal, etc. These products have a mild adaptogenic and immunostimulating effect and are prescribed to patients with immunodeficiencies. When taken prophylactically, such drugs significantly reduce the risk of influenza or respiratory infections, prevent radiation pathology and reduce harm from cytostatics;
• Microbial preparations - Imudon, IRS-19, etc. The drugs act directly on macrophages and monocytes, which, after activation, intensively produce cytokines that trigger immune reactions that promote the elimination of microbes;
• Interferon agents – Anaferon, Viferon. The drugs protect the body from various types of antigenic attacks of bacterial, viral and other origins;
• Synthetic drugs - Amiksin, Trekrezan, etc. Increase general organic resistance to negative external influence and stimulate immune responses;
• Endogenous agents – Thymogen, Timalin. These are drugs based on placental or bone marrow cells or thymus. They restore the normal number of blood cells, cause increased interferon production and immune activity.

It is strictly not recommended to take drugs with adaptogenic or immunomodulatory activity on your own; the need for their use should be determined by an immunologist.

Popular drugs

Trekrezan (250 RUR*)

The adaptogenic immunomodulator Trecrezan stimulates interferon production, corrects and improves the patient's immune status. As a result of using the medication:

• Increases the body's endurance during mental and physical stress;
• Decreasing toxic effects various medications and chemical substances;
• The body becomes especially resistant to oxygen deficiency, temperature changes and other aggressive factors.

Thanks to such effects, Trekrezan is successfully used for therapeutic and prophylactic purposes for respiratory infections, flu or colds. In the presence of stressful influences (for example, lack of oxygen, hypothermia or overheating), it helps to increase the performance and resistance of the body.

This immunomodulator is prescribed for complex treatment alcohol withdrawal or heavy metal poisoning. The drug is contraindicated during pregnancy, children under 12 years of age and pregnant women with lactose intolerance.

Immunal, Echinacea (300 RUR*)

Immunal contains components of plant origin (echinacea juice). The drug provokes an increase in nonspecific immunity. By activating phagocytosis and increasing leukocytes, the drug inhibits reproduction and growth pathogenic microorganisms. In addition, Immunal has antiviral activity against herpes or influenza. The drugs Echinacea and Immunal are analogues, having the same active substance(extract from the herb Echinacea), so they have similar effect.

Both drugs are used:

1. Whenever initial signs flu or cold processes, as well as for the prevention of these pathologies;
2. In order to improve the immune status during long-term treatment with antibiotics;
3. In the treatment of recurrent genitourinary and respiratory pathologies.

Echinacea is contraindicated in case of autoimmune pathologies, immunodeficiency (HIV), AIDS, multiple sclerosis, hypersensitivity to the plant and its components, children under 12 years of age, in the presence of systemic pathologies such as leukemia, tuberculosis, etc. It is not recommended to take it unless particularly necessary and for pregnant women , because there are no definitive research results on the effect of the drug on the fetus and the course of pregnancy.

Immunal in the form of a solution is contraindicated for children under one year of age, and in tablets for children under 4 years of age. The drug should not be taken if you have autoimmune and systemic pathologies such as AIDS or HIV, multiple sclerosis and leukemia, tuberculosis, etc. Immunal should not be taken by persons who have hypersensitivity or intolerance to echinacea and other components of the drug. Unlike Echinacea, Immunal can be taken by nursing and pregnant women, but only with a doctor's prescription.

Immunomax (800 RUR*)

Effective immunostimulant, under the influence of which there is a threefold increase in the activity of cellular structures immune system. Immunomax increases the body's resistance to viruses like herpes or plague, papillomavirus or parvovirus. In addition, the drug protects the body from bacterial microorganisms like chlamydia, staphylococcus, coli, salmonella or mycoplasma, ureaplasma, etc.

Immunomax contraindications:

• Up to 12 years of age;
• Breast-feeding and pregnancy;
• Hypersensitivity to the drug or its individual components.

The drug does not cause any adverse reactions. And in exceptional cases may be prescribed during pregnancy.

Galavit (tablets RUR 300*, injections RUR 600*)

Modern immunomodulator, which is available in the form of suppositories, tablets and powder for injection solution. The medication has an additional anti-inflammatory effect. Galavit is a synthetic immunostimulant and currently has no analogues. The drug has a broad-spectrum effect:

1. It enhances the production of necessary antibodies;
2. Enhances the production of macrophages, which are distinguished by their ability to eliminate pathogenic pathogens;
3. Increases the production of interferons, which promote resistance to various infections;
4. Has an antioxidant effect;
5. It has hepatoprotective activity, i.e. it protects the liver.

Galavit is contraindicated for use in patients under 6 years of age, breastfeeding, pregnant women or people with intolerance of this medicine.

Arbidol (250 RUR*)

Antiviral agent, which has moderate immunomodulatory activity. The drug is indicated for diseases such as:

• ARVI, severe cases respiratory diseases complicated by pneumonic or bronchial processes, types of influenza A and B;
• Pneumonic lesions, complex treatment of chronic inflammation of the bronchi, recurrent herpes, pneumonia;
• Restoration and improvement of immune status, prophylactic administration of the drug after surgery;
• In the complex treatment of acute intestinal lesions rotavirus origin in pediatric patients (over 3 years).

The drug has virtually no contraindications or side effects. It is not prescribed to children under three years of age, as well as to patients hypersensitive to the drug. Among the possible adverse reactions very rarely observed allergic manifestations.

Isoprinosine (600 RUR*)

Tablet drug with antiviral and immunostimulating effects. Means synthetic origin, a purine derivative, is used for diseases such as:

1. Papillomavirus, including with lesions of the genital organs and larynx;
2. Various shapes ARVI and influenza;
3. Shingles and chickenpox;
4. Cytomegalovirus;
5. Various modifications of herpesvirus of all types, as well as herpetic keratitis, genital herpetic lesions etc.;
6. Molluscum contagiosum;
7. Corey;
8. Mononucleosis infectious origin etc.

Among the disadvantages of the drug, patients note the presence of adverse reactions in the form of nausea and vomiting syndrome and epigastric pain, itchy sensation on the skin, joint pain and dizziness, sleep disorders and headaches, exacerbations of gout or intestinal disorders. Since the drug causes an increase in urea in the blood, it is contraindicated in cases of urolithiasis, gout, insufficient renal activity and arrhythmia. In addition, Isoprinosine is contraindicated in children weighing less than 20 kg and under 3 years of age.

Imunofan (500 RUR*)

The drug Imunofan is an immunomodulatory drug with hepatoprotective, detoxification, antioxidant and immunostimulating activity. In addition, the drug prevents the emergence of cellular resistance to drugs antitumor action.

The drug is available in the form of injections, rectal suppositories or nasal spray. Imunofan is effective in treating:

• HIV infections;
• Various types of immunodeficiency conditions;
• Papillomavirus;
• Cytomegalovirus;
• Viral hepatitis different types;
• Herpes;
• In complex antitumor therapy, etc.

The drug is not used in the treatment of children under 2 years of age and pregnant women with a Rhesus conflict with the fetus.

Tiloron (600 RUR*)

The medications Lavomax, Amiksin and Tiloram are analogues, have the same active ingredient (tilorone) and belong to the group of drugs - inducers of interferon synthesis, which have immunomodulatory and antiviral effect. The drugs are produced in tablet form.

1. Lavomax provokes an increase in the formation of antibodies, stimulates bone marrow stem cell structures, and reduces immunosuppressive activity. Used for herpetic and cytomegalovirus infections, viral hepatitis, respiratory and influenza infections in adult patients. Contraindicated for pregnant women, children and adolescents under 18 and breastfeeding.
2. Amiksin has a similar effect and is able to stop viral reproduction. Can be used in pediatrics from the age of 7, however, it is contraindicated during breastfeeding and pregnancy.
3. Tiloram, like Lavomax, is contraindicated in patients under 18 years of age, pregnant and breastfeeding patients. Adverse reactions sometimes include allergic rashes, slight chills and dyspepsia (digestive disorders).

Timalin (500 RUR*)

The drug is produced in the form of a lyophilisate for the preparation of injection solutions. The active substance of the drug is thymus extract, which is obtained by extracting from thymus animals.

The drug is effective when it is necessary to restore immune activity. In addition, while taking Timalin, patients experience an improvement in cellular metabolic processes, hematopoiesis is restored and regeneration is accelerated.

Timalin is indicated:

• With a reduced immune status against the background of various types of soft tissue and bone purulent-inflammatory pathologies;
• For infectious lesions of bacterial or viral origin;
• With inhibition of hematopoietic and immune functions against the background of chemotherapy or radiation treatment tumor and oncological processes, as well as during long-term antibiotic therapy, etc.

The drug has no contraindications and is not prescribed only to people with hypersensitivity to it. In rare cases, the use of Timalin is accompanied by adverse allergic reactions.

There is an analogue based on the same substance - Taktivin.

Riboxin

It is a metabolic regulator and has antiarrhythmic and antihypoxic activity. As a result of taking the drug, blood circulation in the coronary network is normalized and the energy balance of the heart increases. Active substance– inosine. The drug is used only in adult patients in the treatment of myocardial ischemia and arrhythmia caused by taking cardiac glycosides.

Cytoflavin

A multicomponent preparation containing inosine, succinic acid, vitamins B₂ and PP. Cytoflavin is a metabolic drug that improves tissue nutrition and cellular respiration, blood circulation. Has anti-ischemic and neuroprotective activity. Produced in tablets and injections, it is used in the treatment of patients of any age. It is not advisable to use in pregnant and lactating patients.

Can pregnant women take it?

Doctors do not have a clear opinion regarding the use of immunomodulators in pregnant women, however, the majority is inclined to believe that they should not be taken. Most of the funds in this group exist on pharmaceutical market relatively short-lived, so the long-term side effects of taking them are still unknown.

To increase immunity, it is better for pregnant women to adjust their diet, enriching it with vegetables, herbs and fruits, rationally organize their regime, spend more time walking in the fresh air, etc.

In childhood

In the treatment of children, the use of immunomodulators and adaptogens is justified in the following cases:

• Frequent ARVI, colds and flu;
• In the absence of hyperthermic symptoms during respiratory infections and flu;
• For sleep disorders, severe weakness, frequent headaches;
• For food allergies;
• With a noticeable enlargement of the lymph nodes.

Up to 1.5 years of age, immunomodulators are used only in exceptional cases. Older children, strictly according to medical indications, can be given immunomodulators of the interferon group. Give specific names similar means makes no sense, because only a pediatrician should prescribe them. It is better to use them as immunostimulants and adaptogens in children. natural remedies like honey, rose hips, garlic or onions, eucalyptus, etc.

General operating principles

Immunomodulatory drugs are intended to balance the level of cellular structures of the immune system in the presence of autoimmune pathologies. These drugs balance the activities of all immune components, if necessary, suppressing their activity or activating it. The action of adaptogens is aimed at increasing the resistance of organic structures to infectious, viral and other types of external influences.

Immunomodulatory drugs are prescribed to patients with serious health problems. There are a number of pathologies against which the body is unable to resist even the simplest infectious lesions. The most famous similar pathology is a human immunodeficiency virus. To avoid constant colds and flu with any minor hypothermia, such patients are prescribed immunomodulators.

Premature babies also need immunomodulatory therapy, especially when they begin to attend preschool educational institutions. IN similar situation children find themselves in a completely new environment that has its own bacteria and microorganisms, so sometimes during the adaptation period children are prescribed adaptogens, which:

1. Has little effect on nervous system structures;
2. Restore endocrine activity;
3. Accelerate material exchange reactions;
4. Form the body's resistance to adverse external influences;
5. Helps improve performance, tolerance of excessive loads, etc.

At the same time, adaptogenic drugs do not disrupt the processes of normal functioning of the body. They are recommended to be taken by workers in hazardous industries and hard work, athletes and people in a state of stress or stress. depressive disorder. If you take adaptogens during increased mental and physical stress, the drugs will accelerate the body's adaptation without harm to brain and muscle activity.

According to statistics, immunomodulators are among the best-selling drugs in the pharmaceutical market. This is understandable - everyone wants to take a magic pill and not get sick. In addition, manufacturers claim that these products will protect against viruses and improve health. However, doctors themselves have a rather complex attitude towards drugs that are designed to simulate human immunity.

The so-called killer T cells are responsible for our immunity.

When the virus enters the body, they attack it.

Therefore, body aches appear.

If the disease drags on, it means that the killer T cells are tired, in simple terms, and cannot perform their function.

Immunomodulators are substances that stimulate the immune system to regulate the body's defenses. Such substances are obtained from plant or animal tissues using methods genetic engineering and synthesis of chemical compounds.

Indications for which diseases it is prescribed

Immunomodulators are divided into 2 groups. In the first group - potent drugs, which have a lot of serious side effects, so they are not recommended for everyone. They are prescribed when:

• primary lack of immunity;
• immunodeficiencies associated with HIV;
• colds;
• at .

The second group includes products that can be easily purchased without a prescription and that suppress the symptoms of the disease:

• reduce;
• stops runny nose.

They are often advised to be purchased for prevention and in the first days of treatment of the disease.

Classification

By origin, immunomodulators are divided into:

• synthetic;
• natural.

Based on their effect on the immune system, they are classified as:

• immunostimulating;
• immunosuppressive (immunosuppressants).

Immunostimulating drugs include:

• interferons;
• therapeutic vaccines;
• thymus preparations;
• active peptides;
• interleukins;
• mushroom polysaccharides.

Immunosuppressants are a group of the following drugs:

• cytostatics;
• anti-Rhesus and antilymphocyte immunoglobulins;
• hormonal drugs;
• monoclonal antibodies.

Immunostimulants, affecting cellular metabolism, activate cells of the immune system. Immunosuppressants are used in the treatment of autoimmune diseases, suppressing the activity of lymphocytes in the case of or.

Classification and indications for the use of immunomodulators:

Rating of popular drugs

The list of these drugs today is quite wide, starting with inexpensive prices. They are offered at any pharmacy, even if a person is not sick, especially with the onset of cold weather and on the eve of flu epidemics.

For adults

For children

For the treatment of children are provided separate forms release of immunostimulants, which should only be prescribed by a doctor. Unintentional interference with a child’s immune system can cause allergies, autoimmune disorders, and other pathologies.

- for adults and children, they are medications that eliminate the imbalance of various parts of the immune system. Thus, the action of these drugs should be aimed at normalizing immunity parameters, i.e. to reduce high or increase low indicators.

In the Russian Federation, some are effective immunomodulators-registered as immunostimulants, including those of plant origin. It is believed that the use of these drugs leads to an increase in immunity levels, however, this is not entirely true, since immunity levels under the influence of such drugs do not exceed the physiological norm. In connection with the above, it is more correct to use the term immunomodulators.

In this section we will dwell in detail on the description of the various types - immunomodulators, which, depending on their origin, can be divided into three large groups: exogenous, endogenous and synthetic.

Exogenous immunomodulators (bacterial and plant origin)

Among immunomodulators of exogenous origin, bacterial and herbal preparations are distinguished.

Bacterial immunomodulators

Most known drugs of this group are: “imudon”, “IRS 19”, “broncho-munal”, “ribomunil”.

Main indications: Chronical bronchitis, tonsillitis, pharyngitis, laryngitis, rhinitis, sinusitis, otitis.

Contraindications: allergy to medicine, acute stage infections of the upper respiratory tract, autoimmune diseases, HIV infection.

Side effects: The drugs are very well tolerated and are rare allergic reactions, nausea, diarrhea.

Herbal immunomodulators

The most well-known drugs in this group are: “Imunal”, “Echinacea Vilar”, “Echinacea compositum CH”, “Echinacea liquidum”.

Main indications: prevention of ARVI.

Contraindications: allergies to medicine, tuberculosis, leukemia, autoimmune diseases, multiple sclerosis, allergic reactions to pollen.

Side effects: the drugs are very well tolerated, allergic reactions (Quincke's edema) are rare, skin rash, bronchospasm, decreased blood pressure.

Endogenous immunomodulators

Endogenous immunomodulators can be divided into the following groups: drugs isolated from the thymus and bone marrow, cytokines (interleukins, interferons and interferon inducers) and nucleic acid preparations.
drugs isolated from the thymus and bone marrow.

Medicines obtained from thymus tissue (an organ of the immune system) are: “tactivin”, “thymalin”, “timoptin”; from the bone marrow - “myelopid”.

Main indications:

• for preparations from the thymus - immunodeficiencies with a predominant lesion of the T-cell component of immunity, developing in purulent and tumor diseases, tuberculosis, psoriasis, ophthalmic herpes;
• for preparations from bone marrow - immunodeficiencies with predominant damage to the humoral immunity; purulent diseases, as part of complex therapy of leukemia and chronic infectious diseases.

Contraindications: for thymus preparations - allergy to the medicine, pregnancy.
for bone marrow preparations - allergy to the medicine, pregnancy with Rhesus conflict.

Side effects: for drugs from the thymus - allergic reactions.
for bone marrow preparations - pain at the injection site, dizziness, nausea, increased body temperature.
cytokines - interleukins: natural (“superlymph”) and recombinant (“betaleukin”, “roncoleukin”)

Main indications: for natural cytokines - treatment of wounds and trophic ulcers.
for recombinant cytokines: “roncoleukin” - purulent-inflammatory diseases, some malignant tumors; "betaleukin" - leukopenia (reduced number of blood leukocytes).

Contraindications: for natural cytokines - drug allergy, thrombocytopenia, renal and liver failure, epilepsy.
for recombinant cytokines: “roncoleukin” - drug allergy, pregnancy, autoimmune diseases, cardiovascular diseases; "betaleukin" - allergy to a medicine, septic shock, high fever, pregnancy.
Side effects: for natural cytokines - exacerbation of inflammation (short-term)
for recombinant cytokines - chills, fever, allergic reactions.

cytokines - interferons: this class of immunomodulators is very extensive, it includes three types of interferons (alpha, beta, gamma); Depending on their origin, interferons are divided into natural and recombinant. Most common form administration - injection, but there are other forms of release: suppositories, gels, ointments.
Main indications: very different depending on the type of interferon. Interferons are used in the treatment of viral, tumor diseases and even multiple sclerosis. For some diseases, the effectiveness of interferons has been proven by many studies, while for others there is only moderate or even little experience with successful use.

Contraindications: allergies to medications, severe autoimmune diseases, cardiovascular diseases, epilepsy, diseases of the central nervous system, serious illnesses liver, pregnancy, childhood.

Side effects: interferons have undesirable effects of varying severity and frequency drug reactions, which may vary depending on the drug. In general, interferons (injectable forms) are not well tolerated by everyone and may be accompanied by a flu-like syndrome, allergic reactions and other undesirable drug effects.

cytokines are interferon inducers: this class of immunomodulators is represented by substances that stimulate the production of interferons in our body. There are forms of medicine for oral administration, in the form of means for external use, and injectable forms. Trade names interferon inducers: “cycloferon”, “alloferon”, “poludan”, “tiloron”, “neovir”, “megosin”, “ridostin”.

Main indications: treatment of chronic viral infections as part of complex therapy.

Contraindications: allergies to medicine, pregnancy, breastfeeding, children (up to 4 years).

Side effects: allergic reactions.
nucleic acid preparations: “ridostin” and “derinat”.
Main indications: secondary immunodeficiencies manifested by viral and bacterial infections.

Contraindications: allergies to medicine, pregnancy, breastfeeding, children (up to 7 years), myocardial diseases, severe renal and liver failure.
Side effects: allergic reactions, increased body temperature.

Immunomodulators of synthetic origin

This group of immunomodulators is represented by different chemical structure drugs, and therefore each drug has its own characteristics of the mechanism of action, tolerability and unwanted effects. This group includes: “isoprinazine”, “galavit”, “gepon”, “glutoxim”, “polyoxidonium”, “imunofan”, “thymogen”, “lykopid”.

Main indications: secondary immunodeficiencies associated with chronic viral and bacterial infections.

Contraindications: allergy to medication, pregnancy, breastfeeding. "Isoprinasine" is also contraindicated in case of padagra, urolithiasis, chronic renal failure and arrhythmias.

Side effects: allergic reactions, pain at the injection site (for injectable drugs), exacerbation of gout (isoprinazine), etc.

Immunoglobulins

Intravenous immunoglobulins - medications, which are protective blood proteins that protect us from bacteria, viruses, fungi and other foreign microorganisms.

There are immunoglobulins (antibodies) directed against a specific foreign particle (antigen), in which case these antibodies are usually called monoclonal (i.e., all as one clone - the same), but if immunoglobulins (antibodies) are directed against many foreign particles they are called polyclonal, and intravenous immunoglobulins are precisely such polyclonal antibodies. Monoclonal antibodies are medicines of the 21st century that can effectively fight certain tumors and autoimmune diseases. However, polyclonal antibodies are also very useful, because they are successfully used under the most various diseases. Intravenous immunoglobulins, as a rule, consist predominantly of immunoglobulins G, however, there are intravenous immunoglobulins also enriched with immunoglobulins M (“pentaglobin”).

To the main intravenous immunoglobulins, registered in the Russian Federation, include: “intraglobin”, “octagam”, “humaglobin”, “cytotect”, “pentaglobin”, “gamymn-N”, etc.

Main indications: primary immunodeficiencies associated with a lack of immunoglobulin synthesis, severe bacterial infections, autoimmune diseases (Kawasaki disease, Guillain-Barre syndrome, some systemic vasculitis etc.), idiopathic thrombocytopenic purpura, etc.

Contraindications: allergic reactions to intravenous immunoglobulins.
Side effects: allergic reactions, increased or decreased blood pressure, increased body temperature, nausea, etc. With slow infusion, many patients tolerate these drugs well.

The strongest herbal immunomodulators

Root of life ginseng

Ginseng is a herbaceous plant with a magical root, to which people have long attributed various healing and magical properties. It is believed that ginseng root has the ability to restore youth, beauty, and health. The most common ginseng is Far East– in China, Thailand, Korea, Japan and some other countries. It was there that many beautiful legends arose about the “root of life,” as the Chinese call it, who believe that it was born from heavenly fire. The external similarity of the root with a human silhouette among some peoples became the reason for the belief that it can turn into a person, among others - that the root, on the contrary, used to be beautiful girl, which the emperor imprisoned in a tower and turned into ginseng.

But no matter what fairy tales and legends develop around this bizarre plant, it medicinal properties undeniable. Thanks to many years of research, it has been proven that ginseng root contains many active elements: vitamins B 1 and B 2, ascorbic acid, phosphoric acid, iron, manganese, essential oil, starch, fatty oil, cane sugar and etc.

Chinese medicine claims that ginseng increases the body's defenses, and when long-term use has an anti-inflammatory effect. Preparations from ginseng root are recommended for use in case of general loss of strength, nervous exhaustion, for inflammation and other diseases. Ginseng leaves have wound healing properties.

Back in Ancient China, local healers discovered the ability of ginseng to improve memory by affecting the blood vessels of the brain. Scientists have proven that preparations from ginseng root have a beneficial effect on the condition of the blood, increase gas exchange, regulate contractions of the heart muscle, and accelerate the healing of ulcers and wounds.

Over time, they learned to cultivate ginseng, and the first country to establish mass cultivation of ginseng under artificial conditions was Korea.

Official medicine uses ginseng as a tonic and tonic with asthenia, neurasthenia, mental and physical stress, in old age, after long and serious illnesses, with excessive fatigue, with low blood pressure, as well as to strengthen the immune system and improve performance.

Taking medications containing ginseng root increases physical and mental performance, regulates body weight, improves overall well-being, appetite, mood and sleep.

Attention! Use ginseng in one form or another only after consulting with your doctor. It is not recommended to take ginseng for children under sixteen years of age, and it is also better to limit the use of drugs during the summer heat.

Helpful advice

To improve performance and strengthen the immune system, take 30–50 drops in the morning alcohol tincture ginseng.

Pour 2 g of ginseng root into 2 cups of boiling water, add green tea. Heat over low heat for 20–30 minutes, without bringing to a boil. If desired, add honey to taste.

Attention! Contraindications to the use of ginseng preparations: increased arterial pressure, increased excitability, insomnia, sleep disorders, childhood, pregnancy, lactation.

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Vegetable oils Many plants provide people with their oil. In every country there are types of plants that supply the population with oil traditional for a given area: in Asia - cotton, in Spain, Greece and Cyprus - olive, in the USA - corn and sunflower, in China - soybeans. Before

From the book Nutrition author

Vegetable oils Peanut oil has high content fatty acids and lipotropic substances (lecithin, phosphatides), is effective as a choleretic agent. Corn oil contains many antioxidant forms of tocopherols and vitamin E, which helps reduce

From the book Success or Positive Way of Thinking author Philip Olegovich Bogachev

20.1. Plant adaptogens Man is designed in an amazing way: he is upset when he loses wealth, but is indifferent to the fact that the days of his life are irrevocably passing away. Abul-Faraj ibn Harun Almost all popular adaptogens of plant origin are freely sold in our

From the book His Name is AIDS author Vyacheslav Zalmanovich Tarantula

Immunomodulators and immunostimulants Like the other medications listed above, immunomodulators and immunostimulants do not directly target HIV, but can help the human immune system fight this virus. Nowadays, doctors have many tools in their arsenal

From the book Living Food: Raw food diet is the cure for all diseases author Yulia Sergeevna Popova

VEGETABLE FATS Strictly speaking, vegetable fats cannot be called one hundred percent beneficial for our body. If recently nutritionists advised to focus on vegetable oils in the diet, reducing the amount of animal fats, then in our time it has been proven that our

From the book Eco-Friendly Food: Natural, Natural, Living! by Lyubava Live

From the book 700 questions about harmful and medicinal products nutrition and 699 honest answers to them author Alla Viktorovna Markova

Vegetable oils 160. What is cooking fat in its composition? And why is it needed? Culinary edible fat consists of vegetable and animal fats and refined vegetable oils. It is needed for frying and stewing; you can add to the dough.161. Margarine

From the book Directory of Basic medicines author Elena Yurievna Khramova

Immunomodulators Immunomodulators (immunostimulants) - medications that restore balance various structures immune system, i.e. normalizing immunity. These drugs are divided into three subgroups: – natural exogenous

From the book Symphony for the Spine. Prevention and treatment of diseases of the spine and joints author Irina Anatolyevna Kotesheva

Herbal immunomodulators Green pharmacy products are useful for both primary and secondary prevention rheumatic diseases. Just remember that natural immunomodulators cannot be taken during an exacerbation of the disease, but only after 3-4 weeks. IN

From the book Protect Your Body – 2. Optimal Nutrition author Svetlana Vasilievna Baranova

Vegetable oils Peanut oil has a high content of fatty acids and lipotropic substances (lecithin, phosphatides), effective as a choleretic agent. Corn oil contains many antioxidant forms of tocopherols and vitamin E, which helps reduce

From the book Beauty and Women's Health author Vladislav Gennadievich Liflyandsky

Vegetable oils Vegetable oils (corn, olive, sunflower, soybean, etc.) are sources of essential fatty acids and vitamin E. In principle, vegetable oil can be prepared from any nut and pome fruit. It should be borne in mind that all

From the book Encyclopedia of Immunity Protection. Ginger, turmeric, rose hips and other natural immunostimulants by Rosa Volkova

Immunomodulators The regulation of immunity (immunomodulation) of the body is carried out by two opposing systems - immunostimulants and immunosuppressants. Immunomodulators balance all components of the immune system by reducing the activity of some and enhancing