Is the drug "ACC" effective for cough? You can find reviews about this medication a little further. Also from the materials in this article you will learn about the form in which this medicine is produced, what components are included in its composition, how it works and whether it has side effects.
Form, composition, description, packaging of mucolytic agent
In what form can the cough medicine “ACC” be purchased? Effervescent tablets are produced in aluminum tubes and strips and have White color, berry or fruit aroma, as well as round and flat shape.
The medication in question is also available in powder form. It is intended for cooking medicinal solution for oral administration. This form goes on sale in sachets, which are placed in cardboard packaging.
If the medication is prescribed to young children, they are recommended to be given ACC cough syrup. This form of the drug is sold in dark jars with a measuring spoon.
The active component of all of these products is acetylcysteine. It is its presence in the medicine that causes high therapeutic effectiveness medicine.
Pharmacological action of the cough medicine
How does ACC work for cough? The instructions say that this is a mucolytic agent.
Taking the drug helps to dilute sputum, increase its volume, facilitate secretion and subsequent expectoration.
The principle of action of the drug "ACC" is associated with its ability to break all disulfide bonds of sputum mucopolysaccharides (acidic). This effect leads to a decrease in mucus viscosity and depolarization of mucoproteins.
It should be especially noted that this drug remains active even in the presence of purulent sputum.
Features of expectorant medication
How does the cough medication “ACC” affect the human body? Effervescent tablets, as well as syrup and powder, have an antioxidant effect, which is due to the presence of an SH group, which is able to interact with and also neutralize oxidative electrophilic toxins.
The active substance of the drug helps to increase the synthesis of glutathione, which is an important antioxidant factor in intracellular protection. It provides support for the morphological integrity and functional activity of the cell.
Pharmacokinetics of mucolytic
Is the drug "ACC" for cough absorbed (the price of this drug is indicated below)? According to the instructions, when taken orally, this medication is quite well absorbed from the intestines. It undergoes a significant first pass through the liver. This leads to a decrease in its bioavailability.
Plasma protein binding is about 50% (approximately 4 hours after administration). The drug is metabolized in the liver, as well as in the intestinal wall. In the blood, acetylcysteine is observed unchanged, as well as in the form of the following metabolites: N,N-diacetylcysteine, cysteine ester and N-acetylcysteine.
Indications for use
Many patients know how effectively “ACC” helps with cough. Reviews from experts say that indications for the use of this drug are all conditions and diseases in which there is an accumulation of sputum in the respiratory tract.
Thus, we can safely say that the mentioned medication effectively treats:
- tracheitis;
- bronchitis in chronic and acute form;
- bronchiolitis;
- sinusitis;
- obstructive bronchitis;
- laryngitis;
- bronchiectasis;
- cystic fibrosis;
- bronchial asthma;
- Exudative otitis media of the middle ear.
By the way, “ACC” does not cure dry cough. It should only be used for difficult-to-clear sputum (i.e., wet cough).
Contraindications for use
Under what conditions should the drug "ACC" not be prescribed for cough? Reviews from experts say that the following diseases are contraindications to the use of this medicine:
- peptic ulcer;
- fructose intolerance;
- renal failure and hepatitis (especially for children);
- bleeding from the lungs.
It should also be noted that this medication is not recommended for use in hypersensitivity patient to the components of the drug.
How to take the medicine "ACC" for cough?
Reviews from experts report that the dosage of this medicine directly depends on the indications.
Treatment of cystic fibrosis - for people weighing more than 30 kg daily dosage is 800 mg. For children from the 10th day of life to 2 years, the drug is given 50 mg three times a day, and for children 2-5 years old - 400 mg per day.
The daily dosage of this medication is divided into several doses.
"ACC" for cough for children (6-12 years old) is prescribed in the amount of 600 mg. The course of therapy is usually 3-6 months.
For other diseases, this drug should be taken according to a different regimen. To clarify it, you need to go through medical examination and consult your doctor.
For adults and adolescents over 12 years of age, the drug is prescribed in a dosage of 400-600 mg per day.
Therapy for uncomplicated disease should last for 5-7 days. If the disease is chronic or complicated, the course of treatment can be significantly increased (up to six months).
According to the attached instructions, this drug should be taken strictly after meals. ACC powder, as well as effervescent tablets must first be dissolved in 100 ml of any liquid (for example, water, tea or juice).
As for baby syrup, it should be given to the child without dilution. The dosage of this form of medication is determined using a measuring spoon.
Side effects
The use of the drug "ACC" may cause side effects such as diarrhea, heartburn, nausea, stomatitis and vomiting. It should also be noted that this medication often contributes to the development of tinnitus, headaches, increased blood pressure and arrhythmias.
Cases of overdose
If an intentional or mistaken overdose of this drug occurs, patients may experience symptoms such as vomiting, diarrhea, heartburn, stomach pain, and nausea. These symptoms do not require discontinuation of the medication and go away on their own after some time.
Drug interactions
At simultaneous administration"ACC" with life-threatening mucus stagnation may occur. This occurs due to suppression of the cough reflex.
The combination of nitroglycerin and acetylcysteine can enhance the vasodilatory effect of the former.
The drug "ACC" reduces the absorption of tetracycline, cephalosporins and penicillins. In this regard, the listed medications should be taken 2 hours after taking acetylcysteine.
"ACC" is not compatible with antibiotics and proteolytic enzymes.
When acetylcysteine reacts with rubber and metals, sulfides are formed, which have a characteristic odor.
"ACC" cough medicine: price and analogues
You can replace the drug in question with one of the following products: “Fluimucil”, licorice root syrup, “Acestad”, “Mukaltin”, “Mukonex”, “Solvin”, “Acetylcysteine Sediko”, “Gedelix”, “Acestin”, “Bromhexine-Ferein” ", "Lazolvan", "Bromhexine-Acri", "Ambrobene", "Libexin Muco", "Ambrol", "Mucosol", "Broncatar".
As for the price, then different forms This drug may vary slightly. For example, you can buy powder for 170 rubles, syrup for 230, and effervescent tablets for 250.
In this article you can read the instructions for use of the drug ACC. Feedback from site visitors - consumers - is presented of this medicine, as well as the opinions of specialist doctors on the use of ACC in their practice. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications were observed and side effects, perhaps not stated by the manufacturer in the annotation. ACC analogues in the presence of existing structural analogues. Use for the treatment of bronchitis and dry cough in adults, children, as well as during pregnancy and lactation. Various forms of release of the drug to thin the sputum.
ACC- mucolytic drug. The presence of sulfhydryl groups in the structure of the acetylcysteine molecule promotes the rupture of disulfide bonds of acidic mucopolysaccharides of sputum, which leads to a decrease in the viscosity of mucus. The drug remains active in the presence of purulent sputum.
With the prophylactic use of acetylcysteine, there is a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis.
Compound
Acetylcysteine + excipients.
Indications
- respiratory diseases accompanied by advanced education viscous mucus that is difficult to separate (acute and chronic bronchitis, obstructive bronchitis, pneumonia, bronchiectasis, bronchial asthma, bronchiolitis, cystic fibrosis, laryngitis);
- acute and chronic sinusitis;
- Otitis media
Release forms
Powder or granules for making syrup 100 mg.
Syrup 100 ml.
Effervescent tablets 100 mg, 200 mg, 600 mg long.
Solution for injection ACC injection - 100 mg and 300 mg in 1 ml.
Instructions for use and dosage
Powder or effervescent tablets
Adults and adolescents over 14 years of age are recommended to prescribe the drug 200 mg 2-3 times a day (ACC in the form of granules for the preparation of solution for oral administration / orange / 100 mg and 200 mg), or 200 mg 3 (ACC in the form of granules for preparing a solution for oral administration 200 mg) or 600 mg 1 time per day (ACC in the form of granules for preparing an oral solution 600 mg).
Children aged 6 to 14 years are recommended to take 100 mg 3 times a day or 200 mg 2 times a day (ACC in the form of granules for oral solution / orange / 100 mg and 200 mg), or 200 mg 2 times a day (ACC in the form of granules for the preparation of a solution for oral administration 200 mg).
Not available sufficient quantity data on the dosage of the drug in newborns.
For cystic fibrosis, children over 6 years of age are recommended to take the drug 200 mg 3 times a day (ACC in the form of granules for preparing an oral solution /orange/ 100 mg and 200 mg or ACC in the form of granules for preparing an oral solution 200 mg ).
Children aged 2 to 5 years - 100 mg 4 times a day (ACC in the form of granules for the preparation of an oral solution / orange / 100 mg and 200 mg).
For patients weighing more than 30 kg with cystic fibrosis, if necessary, the dose can be increased to 800 mg per day.
In case of sudden short-term colds Duration of treatment is 5-7 days. At chronic bronchitis and cystic fibrosis, the drug should be used for a longer period of time to prevent infections.
The drug should be taken after meals. Additional fluid intake enhances the mucolytic effect of the drug.
Rules for preparing the drug
ACC in the form of granules for the preparation of a solution for oral administration /orange/ 100 mg and 200 mg: 1/2 or 1 sachet (depending on the dose) dissolved in water, juice or iced tea and taken after meals.
ACC in the form of granules for the preparation of a solution for oral administration 200 mg and ACC in the form of granules for the preparation of a solution for oral administration 600 mg: 1 sachet is dissolved with stirring in 1 glass hot water and drink it hot if possible. If necessary, you can leave the prepared solution for 3 hours.
Syrup
Adults and adolescents over 14 years of age are prescribed 10 ml of syrup 2-3 times a day (400-600 mg of acetylcysteine).
Children aged 6 to 14 years - 5 ml of syrup 3 times a day or 10 ml of syrup 2 times a day (300-400 mg of acetylcysteine).
Children aged 2 to 5 years are prescribed 5 ml of syrup 2-3 times a day (200-300 mg of acetylcysteine).
For cystic fibrosis, children over 6 years of age are recommended to take the drug 10 ml of syrup 3 times a day (600 mg of acetylcysteine); children aged 2 to 6 years - 5 ml of syrup 4 times a day (400 mg of acetylcysteine).
For short-term colds, the duration of use is 4-5 days. For chronic bronchitis and cystic fibrosis, the drug should be used for a longer period of time to prevent infections. At long-term illnesses The duration of therapy is determined by the attending physician.
The drug is taken orally after meals. Additional fluid intake enhances the mucolytic effect of the drug.
ACC syrup taken using a measuring syringe or measuring cup contained in the package. 10 ml of ACC syrup corresponds to 1/2 measuring cup or 2 filled syringes.
Using a measuring syringe
1. Open the bottle cap by pressing on it and turning it counterclockwise.
2. Remove the cap with the hole from the syringe, insert it into the neck of the bottle and press in until it stops. The stopper is designed to connect the syringe to the bottle and remains in the neck of the bottle.
3. It is necessary to insert the syringe tightly into the stopper. Carefully turn the bottle upside down, pull the syringe plunger down and draw the required amount of syrup (ml). If air bubbles are visible in the syrup, press the plunger all the way and then refill the syringe. Then return the bottle to its original position and remove the syringe.
4. The syrup from the syringe should be poured onto a spoon or directly into the child’s mouth (into the cheek area, slowly, so that the child can swallow the syrup). While taking the syrup, the child should be in an upright position.
5. After use, you should rinse the syringe clean water.
Ampoules for injections
Adults are prescribed intravenously or intramuscularly at 300 mg (1 ampoule) 1-2 times a day.
Children aged 6 to 14 years are prescribed IV or IM 150 mg (1/2 ampoule) 1-2 times a day.
For children under 6 years of age, it is preferable to oral therapy, however, if indicated and necessary parenteral administration daily dose is 10 mg/kg body weight.
For children under 1 year of age, intravenous administration of the drug is possible only for health reasons in a hospital setting.
The duration of therapy is determined individually.
For chronic bronchitis and cystic fibrosis application of ACC INJECT for a long time can be combined with oral administration of the drug to prevent infections.
The mucolytic effect of acetylcysteine increases with increased fluid intake.
Rules for injections
With intramuscular injection, when performing a shallow injection and in the presence of increased sensitivity, a slight and quickly passing burning sensation may occur, therefore it is recommended to administer the drug to patients in a supine position and deep into the muscle.
For intravenous administration, the first dose must be diluted with 0.9% sodium chloride solution or 5% dextrose solution in a 1:1 ratio. The drug should, if possible, be administered by infusion.
IV injections should be administered slowly (over 5 minutes).
Side effect
- headache;
- noise in ears;
- stomatitis;
- diarrhea;
- vomit;
- heartburn;
- nausea;
- drop in blood pressure;
- tachycardia;
- development pulmonary hemorrhage as a manifestation of a hypersensitivity reaction;
- bronchospasm (mainly in patients with a hyperreactive bronchial system with bronchial asthma);
- skin rash;
- hives.
Contraindications
- stomach ulcer and duodenum in the acute phase;
- hemoptysis;
- pulmonary hemorrhage;
- pregnancy;
- lactation period (breastfeeding);
- children under 2 years of age (the drug is in the form of granules for the preparation of a solution for oral administration /orange/ 100 mg and 200 mg, syrup and ACC 200);
- children under 6 years of age (the drug is in the form of granules for the preparation of a solution for oral administration, 200 mg);
- children under 14 years of age (the drug in the form of granules for the preparation of a solution for oral administration 600 mg and ACC Long);
- hypersensitivity to acetylcysteine and other components of the drug.
Use during pregnancy and breastfeeding
Due to insufficient data, the use of the drug during pregnancy is contraindicated.
For syrup: use of the drug during pregnancy is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.
If it is necessary to use the drug during lactation, the issue of stopping breastfeeding should be decided.
Use in children
Contraindicated for children under 2 years of age (the drug in the form of granules for the preparation of an oral solution /orange/ 100 mg and 200 mg, syrup and ACC 200), up to 6 years of age (the drug in the form of granules for the preparation of an oral solution 200 mg) , up to 14 years (the drug in the form of granules for the preparation of a solution for oral administration 600 mg and ACC Long).
special instructions
For bronchial asthma and obstructive bronchitis acetylcysteine should be prescribed with caution under systematic monitoring of bronchial patency.
When using acetylcysteine, very rarely cases of severe allergic reactions such as Stevens-Johnson syndrome and Lyell's syndrome. If changes in the skin and mucous membranes occur, the patient should immediately stop taking the drug and consult a doctor.
When dissolving the drug, it is necessary to use glass containers and avoid contact with metals, rubber, oxygen, and easily oxidized substances.
You should not take the drug immediately before bedtime (the preferred time of administration is before 18.00).
During development side effects the drug should be discontinued.
ACC (in the form of granules for the preparation of solution for oral administration / orange / 100 mg and 200 mg) 100 mg corresponds to 0.24 XE, 200 mg - 0.23 XE.
Impact on the ability to drive vehicles and operate machinery
Information about the effect of the drug on the ability to drive vehicles and potentially engage in others dangerous species activities requiring increased concentration attention and speed psychomotor reactions, are missing.
Drug interactions
At simultaneous use acetylcysteine and antitussives may cause dangerous mucus stagnation due to suppression of the cough reflex (use the combination with caution).
When taking ACC with vasodilators and nitroglycerin simultaneously, the vasodilator effect may be enhanced.
There is a synergism between acetylcysteine and bronchodilators.
ACC is pharmaceutically incompatible with antibiotics (penicillins, cephalosporins, erythromycin, tetracycline and amphotericin B) and proteolytic enzymes.
Acetylcysteine reduces the absorption of cephalosporins, penicillins and tetracycline, so they should be taken orally no earlier than 2 hours after taking acetylcysteine.
When acetylcysteine comes into contact with metals and rubber, sulfides with a characteristic odor are formed.
Drug analogues ACC drug
Structural analogues of the active substance:
- N-AC-ratiopharm;
- N-acetylcysteine;
- Acestine;
- Acetylcysteine;
- Acetylcysteine SEDICO;
- Acetylcysteine solution for inhalation 20%;
- Acetylcysteine solution for injection 10%;
- Mukobene;
- Mucomist;
- Mukonex;
- N-AC-ratiopharm;
- Fluimucil;
- Exomyuk 200.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
Effective and inexpensive analogues-substitutes Acc
ACC treats lesions of the respiratory tract that are complicated by difficult sputum separation, such as bronchitis, tracheitis, pneumonia. Original remedy based on Acetylcysteine is quite popular due to its high efficiency. However, the drug is no exception to the rule, and it also has a number of cheap analogues, like many other drugs. Below we will talk about such substitutes and individual characteristics specific positions.
The essence of the action
The distinctive properties of the drug ACC are determined by substance Acetylcysteine, which acts against cough as follows:
- Mucolytic. In other words, it reduces the viscosity of sputum, which further accelerates the process of its removal.
- Reduces ability bacterial cells to adhesion, or adhesion to the mucous layer of the bronchi.
- Antioxidant properties help neutralize the harmful effect of free particles, which, when entering the lungs with air, can be provocateurs of the disease.
- Anti-inflammatory the effect is observed due to the elimination of pathogenic factors (microbes, toxins) through antioxidant activity.
What does the drug treat?
Indications for use:
The drug is used for diseases of the respiratory tract affecting both the upper and lower section. The main point that unites all the indications of the pharmaceutical product is the presence of sputum formation, which, due to its thick, viscous consistency, does not drain well, which further forms an abundant accumulation of mucous secretion in the bronchi.
Some of the indications with characteristic hard-to-clear sputum:
- Bronchitis acute, chronic, obstructive;
- Inflammation of the trachea, laryngotracheitis;
- Bronchial asthma;
- Bronchiectactic disease;
- Pneumonia, lung abscess;
- Pulmonary obstructive disease (COPD);
- Bronchiolitis, cystic fibrosis;
- Sinusitis, otitis media.
The benefits of the medicine for the above diseases chronic noticed in reducing the severity and frequency of exacerbations, with acute forms- the onset of recovery is accelerated.
It is noteworthy that the mucolytic qualities of ACC similarly extend to purulent-exudative processes.
Contraindications
- The appearance of bloody spots in expectorated mucus;
- Pulmonary hemorrhages;
- Exacerbation of stomach and duodenal ulcers;
- Pregnant and breastfeeding women;
- Personal intolerance to Acetylcysteine. This is indicated by itching, headache, and runny nose of non-inflammatory origin.
ACC, dosed at 100 and 200 mg, is prohibited for children under 2 years of age. The enhanced dosage form of 600 mg is dangerous for children under 14 years of age.
Possible negative effects
In rare cases there may be: nausea, vomiting, heartburn, skin rashes and itching.
Patients with liver or kidney failure require more gentle therapy with this mucolytic, because most of Metabolic transformations are carried out by the liver, and primary excretion from the body is carried out by the kidneys.
Important instructions for use
All forms of ACC are used orally after meals. The duration of treatment depends on individual needs, but for colds it most often lasts 5-7 days. It is advised to avoid taking it immediately before going to bed and take it until 18.00. When using antibiotics simultaneously with a pharmaceutical drug, a break between their consumption of 1-2 hours is necessary.
Introductory instructions for use:
- Standard method Taking the drug for adults and children over 14 years of age is: 200 mg in 2-3 approaches per day.
- Children from 6 to 14 years old 100 mg 2-3 per day is indicated.
- For ages 2 to 6 years 1 effervescent tablet of 100 mg is recommended once a day. If it is syrup or soluble granules 100 mg, take it 2-3 times a day.
- If you have a very severe cough The recommended dosage is 600 mg, which should not be taken more than once a day.
- If you are using a syringe dispenser, attached to baby syrup, it must be washed each time with clean water at the end of use.
- Effervescent tablets must be used immediately after preparing the solution .
- Granules can be diluted with water, juice or tea drink.
Additional therapeutic measure, which accelerates the healing process, is an increase in the volume of fluid consumed, which has a positive effect on the mucolytic dynamics of the expectorant.
How much does ACC cost: price in pharmacies
The cost of German medicine starts from 120 rubles. and reaches 600 rubles. Any drug in the line can be purchased without a prescription.
List of synonyms of Russian and foreign production
The table contains examples of analogs of a wide variety of dosage forms. The indicated absence of some items is meant at the time of writing only on designated pharmacy web resources, but does not indicate a shortage of a particular drug in pharmacies throughout the country as a whole, including in the regions of Moscow and St. Petersburg.
Rinofluimucil (Italy)
The only one of the listed analogues used externally. The spray can replace internal medications if you have rhinitis with thick mucus.
Espa-naz (Germany)
Generic available High Quality. Orange flavor mucolytic has an expectorant effect on productive cough, inhibiting the accumulation of mucus in the bronchi and facilitating its unhindered discharge.
Fluimucil (Italy)
A European synonym with a lower cost, while maintaining compliance with quality requirements.
Regarding the timely use of Fluimucil for cough, a number of experts note its benefits, which can be traced to a reduction in the need antibacterial therapy. There is also a significant reduction in the severity of inflammation, which in turn prevents complications. A decrease in general intoxication is obvious, which is greatly facilitated by the antioxidant properties of Acetylcysteine, which is part of the composition.
Thoraxol Solution Tablets (Russia)
Domestic relatively inexpensive substitute, of interest modern form dispersible tablet. Relief of cough associated with the formation of viscous sputum, as if acute or chronic type, occurs by stimulating the activity of the ciliated membrane of the bronchi and by reducing the viscosity of mucous formations. All this together creates conditions for faster spontaneous cleansing of the surface of the mucous layer.
It is worth considering that Thoraxol only works if there are lesions in the lower part of the section respiratory system: bronchitis, obstructive disease, pneumonia.
The active substance does not lose its mucolytic qualities regardless of the method of administration, and there are several of them:
- Split the tablet in half and drink the whole tablet without water.. Once in the stomach, it quickly begins to dissolve. This method is convenient if you do not have time to prepare a portion of the medicine.
- Dissolve in 20 ml of water, then immediately take the resulting suspension.
- Drink a whole one with a small portion of water.
Lactation and the first three months of pregnancy are the main contraindications for Thoraxol.
Neo-bronchol (Germany)
Cheaper expectorant tablets, the main ones the advantages of which are:
- Lack of sugar (sorbitol serves as a sweetener);
- The type of dosage form intended exclusively for resorption does not require any additional manipulations.
The drug acts within the first half hour after administration and continues to reveal mucolytic activity after 6-12 hours.
In rare situations, the undesirable effects of Neo-bronchol are expressed skin reactions and stomach upset.
Ambroxol (RF)
An inexpensive way to cope with difficult things wet cough. The description of the pharmacological route of action of Ambroxol has already been mentioned above. The types of dosage forms produced by Russian companies are varied: syrups, regular tablets, solutions. Tablets cost the least, but attracts the most attention solution for inhalation as the most modern method mucolytic therapy .
Some of the advantages of the inhalation route of administration of Ambroxol:
- Rapid access to the site of inflammation;
- A comfortable level of hydration of the respiratory organs, namely the bronchial mucosa, is achieved;
- The natural physiological outflow of mucus and its dilution are improved.
Taken together, these factors significantly accelerate the process of onset of the therapeutic effect.
Bromhexine is the cheapest alternative from Germany
The main goal of Bromhexine is to eliminate the high coefficient of mucus thickness, which for this reason does not clear well and causes a cough reflex.
Interestingly, after the biotransformation of Bromhexine in the liver, the active metabolite Ambroxol is formed. It is he who ultimately determines all its properties.
Conclusions on available replacements
It is unacceptable to combine cough treatment with an expectorant group with an antitussive group, otherwise the suppression of the cough reflex by the latter will lead to the opposite effect - difficulties will be created in removing accumulated mucus from the bronchi. In any case, the correct selection of treatment should take place with the participation of a doctor in order to identify hidden, indolent symptoms disease, thereby avoiding spillover acute condition into chronic.
Article rating
Inflammatory infectious processes are the most common pathologies among children and adults. There are many drugs against diseases of this group. In most cases, such medications have a targeted effect.
Characteristics of ACC
Modern pharmaceutical companies offer a wide selection of drugs to eliminate phlegm, relieve coughs and treat the respiratory tract. One of the medicines that has earned positive reviews, is ACC.
The medication is available in the form of powder for suspension and dissolving tablets. The remedy is recommended for the treatment of tracheitis, bronchitis, sinusitis, laryngitis and other similar diseases.
The product is effective in its action, however, in some cases its composition (acetylcysteine, sodium bicarbonate, mannitol, ascorbic acid, sodium citrate) may be contraindicated or the patient may experience side effects.
In such cases, analogues of ACC are prescribed, which have a similar mucolytic effect. The attending physician will advise how to replace the original drug, taking into account all the characteristics of the patient’s body.
The cost of the ACC drug is from 250 rubles.
Lazolvan
The drug ACC Long, but it cannot be called cheap, since the price is almost the same. It is designed to provide an expectorant effect when coughing, due to liquefaction and elimination thick phlegm from the lungs. In addition to the main effect, Lazolvan promotes self-cleaning of inflamed areas from infection.
The drug begins to act after half an hour due to rapid penetration into the blood.
The drug contains the following components:
- ambroxol (active substance);
- acacia gum;
- karion;
- soritol;
- essential oil of mint and eucalyptus.
The product is available in the form of tablets, syrup, lozenges and solution. Depending on the form of release, the composition of the drug and its cost may vary.
Indications include a number of respiratory tract diseases in chronic and acute forms:
- pneumonia;
- bronchitis;
- bronchial asthma;
- cough;
- other diseases.
Before starting treatment with Lazolvan, you should be sure that there are no contraindications (pregnancy in the second and third trimester, kidney pathologies and allergies to the composition).
When treating children, it is necessary to correctly select the type of drug relative to its release form. Lozenges and syrup are recommended for children.
Which is better to choose ACC or Lazolvan?
The drugs cannot be named structural analogues, because active substance they have different things. The countries of origin are also different. If we compare drugs by release form, then Lazolvan wins here, which is produced in five forms - tablets, solution, syrup, capsules and spray. ACC has only three forms of release - effervescent tablets, syrup and granules for preparing a solution.
Both drugs are intended to solve the same problem, sputum discharge, but their mechanisms of action are different. The advantage of ACC is its antibacterial and antitoxic effect. Pediatricians often prescribe Lazolvan, as it can be used with early age, and ACC only from two years old.
To summarize, it is difficult to say with any certainty which drug is better, so before purchasing a drug, it is best to rely on your doctor.
Ambrobene
Unlike original drug, Ambrobene costs much less (from 110 rubles). For this reason, this drug is often preferred. In addition to its low cost, the advantage of Ambrobene is its effective expectorant effect on coughs.
The effect on the inflamed area begins after 30 minutes and lasts up to 12 hours. With regular use, a cumulative effect is established.
In pharmacies you can buy Ambrobene in the form of tablets, capsules, syrup, as well as a solution for inhalation and internal administration. For complex forms of respiratory tract diseases, inhalation with the solution is recommended.
The capsules contain:
- ambroxol;
- sodium (carboxymethylcellulose);
- colloidal silicon;
- cellulose;
- titanium dioxide.
The ACC analogue is used according to the following indications:
- bronchitis varying degrees development;
- pneumonia;
- asthma (bronchial);
- and others.
The list of contraindications is slightly longer than that of Lazolvan:
- epileptic syndrome;
- intolerance to components;
- stomach or duodenal ulcer;
- pregnancy in the first trimester and lactation.
What is better ACC or Ambrobene?
The medicines are not structural analogues, since they have different active substances, but despite this, both have the same task, to eliminate phlegm and relieve the patient from coughing. By dosage forms ACC also loses to its counterpart (three versus five).
Ambrobene has a number of advantages over ACC:
- analgesic effect;
- antiviral effect;
- removal of toxins from the body;
- elimination of inflammation.
If we compare drugs by price, then the ACC analogue clearly wins. Pack of 20 Ambrobene tablets. in an online pharmacy it costs about 145 rubles, and the same package of ACC tablets (by number of pieces) costs about 495 rubles.
To summarize, we can say that ACC is in many ways inferior to its analogue, but what would be better suited Only a doctor will determine the treatment.
Fluimucil
If we consider cheap analogues of ACC, then we can pay attention to the drug Fluimucil. The cost of the drug is 130 rubles.
The product has similar properties. Its main purpose is to remove phlegm when coughing due to the antioxidant and mucolytic effect of use. After several uses, the sputum thins and leaves the bronchi freely.
Fluimucil is sold in pharmacies in the form of solutions for internal reception, carrying out inhalations and intramuscular injection. Effervescent tablets and dissolving granules are also available.
The ACC analogue in the form of a solution consists of a group of substances:
- acetylcysteine;
- sodium benzoate;
- sodium (carmellose);
- methyl parahydroxybenzoate;
- sorbitol;
- sodium hydroxide and saccharinate.
The tablets also contain the active substance, as well as sodium bicarbonate and aspartame.
A cheap analogue of ACC for cough is used for therapeutic purposes for diseases:
- pulmonary atelectasis;
- bronchitis and its varieties;
- cystic fibrosis;
- pneumonia;
- tracheitis;
- emphysema;
- otitis;
- sinusitis;
- other pathologies of the respiratory tract.
The drug has multiple contraindications. The main ones include:
- peptic ulcers of the gastrointestinal tract (gastrointestinal tract);
- child's age up to two years (solution up to 6 years, and tablets up to 18 years);
- lactation;
- individual reaction to the composition.
Particular attention should be paid to relative contraindications.
What is better ACC or Fluimucil?
Both drugs have the same active ingredient - acetylcysteine, therefore they are structural analogues. Taking both remedies by the end of the second day will significantly reduce the cough by eliminating phlegm, and after a few days it will disappear completely.
The differences between the drugs lie in the forms of release. For example, ACC has a syrup, which Fluimucil does not have, but the second one has an inhalation solution that allows you to use the drug from an early age.
Pulmonologists consider the big disadvantage of ACC to be the fact that it does not have a solution for inhalation, as well as injections, due to which the active substance of the medicine would reach its goal faster.
If you compare the prices of drugs in online pharmacies, then effervescent cough tablets of 20 pcs. they cost about the same (about 500 rubles), but out of 10 pcs. Fluimucil tablets will be cheaper (almost 200 rubles). Otherwise the price is various shapes approximately the same.
To summarize, we can say that Fluimucil is a worthy analogue of ACC.
Bromhexine
Another expectorant medicine is Bromhexine. Generic refers to drugs that do not have a stimulating effect on the motor functionality of the respiratory organs.
When taking Bromhexine, there is a decrease in viscosity internal secret bronchi, due to which the stagnant phlegm that comes out when coughing occurs. At the same time, the medicine has a local anti-infective effect, helping to reduce inflammatory process.
The components of the drug act when they accumulate in the body. Therefore, the medicine is used for a course of treatment. The effect begins to be observed after three to four days.
- hydrochloride (bromhexine);
- sugar (milk);
- ruberosum;
- calcium stearate.
Indications include pathologies of the lungs and bronchi:
- bronchial asthma;
- complications of bronchitis;
- pneumoconiosis;
- emphysema;
- pneumonia;
- pulmonary tuberculosis;
- cystic fibrosis.
Contraindications to Bromhyxine are solely reactions to the constituent substances.
Which is better ACC or Bromhexine?
Medicines are not structural analogues, since they have different active ingredients. Both medications are mucolytic agents and affect the thinning of sputum and the elimination of cough.
It is not uncommon for doctors to prescribe both drugs at the same time, since the effect of Bromhexine directly suppresses cough, while ACC acts remotely. This ligament has a double effect and allows you to speed up the recovery time. But this does not mean at all that you can decide on your own complex application medicines. Everything depends on clinical picture inflammatory process, so you need to consult your doctor.
Bromhexine is the cheapest analogue and its average cost among all forms is 109 rubles, and the average cost of ACC among all forms is 301 rubles.
When making a decision when choosing a medicine, you should not rely only on the price, since small role The clinical picture of the disease plays a role, and here you should rely on the doctor’s recommendation.
Ascoril
The drug Ascoril - universal remedy With combined action for bronchodilator and expectorant effect. Ascoril is recommended for therapeutic effects in bronchial and pulmonary inflammation in severe form.
When taking the medication, an expectorant effect is observed, sputum is thinned, pulmonary spasms are eliminated and natural beta receptors of the respiratory system are stimulated.
Ascoril is a medicine with average price. Its cost is from 220 to 270 rubles.
The combined composition includes several active components:
- guaifenesin;
- salbutamol;
- Bromhexine.
Additional composition:
- silica;
- calcium hydrophosphate;
- magnesium stearate;
- silicon dioxide.
A drug with a similar ACC instructions according to application it is intended for the treatment of:
- tuberculosis;
- whooping cough;
- asthma;
- tracheobronchitis;
- pneumonia;
- other diseases.
Ascoril is contraindicated in myocarditis, pregnancy, breastfeeding, pressure disorders, gastrointestinal ulcers. You can study the contraindications in more detail in the annotation for the drug.
What is better ACC or Ascoril?
The drugs are not structural analogues, since they do not have the same active substance. Unlike all other ACC analogues, Ascoril has three active components, therefore it has a more powerful healing effect.
A special difference between the drug is that Ascoril cannot be used when coughing, without signs of suffocation.
If you compare the drug by price, then in some places ACC will cost more, and in others Ascoril. For example, Ascoril tablets of 20 pcs. cost 354 rubles, and ACC tablets of 20 pcs. cost 501 rubles. ACC syrup 200 ml. costs 302 rubles, and Ascoril syrup with the same volume will cost 406 rubles.
Conclusion
If you decide to use ACC analogues, you should read the instructions in full and consult your doctor. Independent selection of substitutes can provoke an exacerbation concomitant diseases or cause serious side effects.
Everyone knows that cough and mucus formation exist defensive reaction body. It is also well known that the treatment of these conditions must begin with establishing the cause. But not everyone knows the advisability of using mucolytics Fluimucil or ACC - agents that dilute sputum to facilitate its separation, although complex treatment respiratory tract, these drugs have a significant impact on the success of the enterprise.
Firstly, they enhance the effectiveness of mechanical removal, along with mucus and phlegm, of foreign agents and toxins, in fact, what the body coughs and “sniffles” for (by the way, they are also used with great success to treat ENT diseases). Secondly, the mucus and sputum itself, produced in the upper and lower respiratory tracts, contains immunoglobulins, lysozyme, opsonins, which lose their bactericidal and barrier properties if the secretion is excessively viscosity. So, in order to increase the productivity of natural protective mechanisms, mucolytic agents are prescribed, the most popular representatives of which in our country are ACC or Fluimucil with a good safety profile and proven effectiveness. Let's look at their similarities and differences.
Fluimucil and ACC - what is the difference?
Release forms and their diversity are where Fluimucil clearly differs from ACC. Both drugs are presented in various variations, allowing their use depending on age and method of delivery to the body. To make it easier to navigate, let’s imagine the difference between their rulers in the form of a table.
| Fluimucil | ACC |
|---|---|
| Effervescent tablets: | |
| 600 mg - 10 or 20 pcs. | 100 mg - 20 pcs (for children), 200 mg each - 20 pcs., 600 mg each (ACC Long) - 10 or 20 pcs. |
| Granules for preparing the solution: | |
| 200 mg each - 20 sachets | 100 mg each - 20 sachets (orange flavor for children), 200 mg each - 20 sachets (orange flavor), 200 mg each - 20 sachets (for preparing a hot drink, orange flavor), 200 mg each - 20 sachets (for preparing a hot drink, honey and lemon flavor) |
| Syrup for children: | |
| - | 100 ml bottles (20 mg per 1 ml) |
| Oral solution: | |
| 200 ml bottles (40 mg per 1 ml) | - |
| Solution for inhalation and injection: | |
| 5 ampoules of 3 ml (100 mg in 1 ml) | - |
The table shows that ACC has a larger range of release forms and flavors than Fluimucil. All forms of ACC except syrup are available in different doses acetylcysteine, tastes and even the temperature of the finished drink. This allows you to more flexibly calculate the dosage, which is especially important in childhood(you can give not only syrup, but also effervescent tablets or granules of 100 mg). It is more convenient for adults to manage the number of doses per day, for example, you can take 200 mg tablets 3 times a day, or you can take ACC Long containing ACC only once a day. daily norm acetylcysteine. Fluimucil effervescent tablets, on the contrary, are available only in high dose, designed for one appointment.
However, Fluimucil has a very important advantage - it is produced in ampoules, the solution from which is also used for inhalation. Naturally, the shorter and natural way delivery to Airways has a positive effect on the speed of its action and effectiveness compared to oral forms. This is especially true in acute conditions.
What is better for children - ACC and Fluimucil?
Both drugs are contraindicated in children under two years of age. Correct selection the quantities in each specific case should be determined by a pediatrician; the recommended dosages of acetylcysteine, which should not be exceeded regardless of the release form of Fluimucil or ACC, are as follows:
- from 2 to 6 years - 2-3 times a day, 100 mg (total 200-300 mg per day);
- from 6 to 14 years - 3 times a day, 100 mg or 2 times 200 mg (total 300-400 mg per day);
- over 14 years old - 2-3 times a day, 200 mg (total 400-600 mg per day).
In general, despite the fact that ACC and Fluimucil are the same thing, the former offers a greater variety of types of medicine and its tastes for children younger age, including cherry syrup, which comes with a measuring device (syringe or measuring cap) in the package, allowing you to dose the medicine correctly.
Drinking plenty of fluids is one of the keys to the success of treatment with acetylcysteine-based mucolytics. Alkaline ones help them with this best mineral water. Also, to increase the effectiveness of therapy, it is desirable to maintain optimal air humidity in the room.
What is the difference in contraindications and price between Fluimucil and ACC?
Both mucolytics are contraindicated in case of hypersensitivity to acetylcysteine or auxiliary components; up to two years of age (up to 14 years in 600 mg tablets), pregnant and lactating women (in special cases strictly under the supervision of a doctor); For separate forms ACC: fructose intolerance, glucose-galactose deficiency.
As for the question of choosing Fluimucil or ACC - which is better to buy, the situation here is ambiguous. In almost all similar forms of release, Fluimucil will be only slightly cheaper than its opponent. But for a package of 10 effervescent tablets of 600 mg - Fluimucil or ACC Long, the former will cost almost half the price. Most likely, such a significant difference is associated with the country of production, because in the same dosage (600 mg), but in packages of 20 tablets, these drugs cost almost the same. Thus, if you need long-acting effervescent tablets for adults, it is more profitable to take Fluimucil in 10 pieces; in other cases, the price difference is insignificant.
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