Is terzhinan dangerous? High effectiveness of terzhinan suppositories in the fight against female diseases

Quite often, women turn to gynecologists with complaints of discharge, itching and burning in the genital area. Such phenomena bring a lot of discomfort to both the woman herself and her sexual partner.

Sex ceases to be enjoyable, and your health gets worse every day. The causes of such symptoms may vary.

This is both thrush and aerobic bacteria, and pathogenic microorganisms, and inflammatory processes on the vaginal mucosa. The drug Terzhinan, widely used in medical practice because of its versatility.
Terzhinan is used in case of detection of genital ureaplasmosis, vaginitis, including those caused by Trichomonas and combined, colpitis, inflammation of the appendages, and thrush.

Vaginal tablets are also administered to prevent inflammatory processes before and after surgical intervention, including during termination of pregnancy, or after installation intrauterine device. Terzhinan is also indicated as a remedy that effectively relieves unpleasant and painful sensations after treatment of cervical erosions. If a woman is diagnosed with candidiasis before giving birth, then with the help of Terzhinan it is possible to prevent infection of the child during passage through the birth canal and avoid possible complications. This wide range of application is ensured by the special composition of the drug.

Composition of Terzhinan

Nystatin. This antifungal antibiotic effectively fights the growth of Candida fungi that cause thrush.

Ternidazole. The antiseptic inhibits the proliferation of Trichomonas, Gardnerella and other types of bacteria.

Neomycin sulfate. The antibacterial effect of the drug can destroy vegetative and dormant varieties of aerobic microorganisms, which include Klebsiella, Enterobacter, Escherichia coli, Pseudomonas aeruginosa, and staphylococci.

Prednisolone. Normally, this glucocorticosteroid hormone is produced in the required quantity by the adrenal glands. If the production of prednisolone is impaired, this can lead to all sorts of manifestations on the vaginal lining, swelling, pain, redness and itching.

Excipients such as starch, lactose monohydrate, colloidal silicon dioxide, magnesium stearate help maintain the bactericidal acidity of the vaginal mucosa and protect it from damage.

Sex while taking Terzhinan

First of all, it should be remembered that all diseases that are treated with Terzhinan must be eliminated not only on the part of the woman, but also on the part of the man. To do this, sexual partners must undergo antibacterial treatment. If you neglect this point, then all the troubles that occur with any disease will come back. It is best to completely abstain from sex during treatment, which is also indicated in the instructions for this medicine, however, some doctors make concessions while taking Terzhinan and allow partners to live their usual sex life.

Naturally, only subject to the mandatory use of a condom, and complete absence any side effects from both genital organs. For example, some women may experience strong feeling burning during sex, or some time after it, and men may complain of some discomfort and unpleasant sensations. In this case, it is better to completely abstain from sexual activity until the end of the course of treatment. It should also be taken into account that sexual intercourse must occur only before the introduction of the next evening vaginal tablet, and not after.

Features of using Terzhinan

Terzhinan belongs to the category of drugs that are safe even during pregnancy, as well as during breastfeeding. But it was precisely at this time future mom often faces gynecological problems due to a decrease in the body's defenses. Therefore, even if a woman’s menstruation is delayed during therapy, it is not advisable to stop treatment. Another undoubted advantage of these tablets is the fact that even menstruation is not an indication for a break in treatment. This allows you to quickly get rid of the disease without adjusting to the menstrual cycle. Alcohol does not affect the effectiveness of this drug.

Terzhinan is produced in the form of vaginal tablets, which, before insertion into the vagina, must be moistened for 30 seconds in water, or held for 2 minutes in a damp hand. After administering the tablet, you should lie down for 10-15 minutes. It is best to carry out this procedure before bedtime. In the morning, yellowish discharge may appear, which is normal during treatment with Terzhinan. If the main goal is to normalize the disturbed vaginal microflora and relieve inflammation, then the duration of treatment is six to ten days, depending on the diagnosis and the doctor’s prescription. The reason for using Terzhinan is thrush? Then the course of therapy doubles in time. Three days after the end of treatment, you must undergo tests that will confirm your recovery. In some cases it may be necessary repeat course taking Terzhinan.

Despite the generally recognized safety of the drug, the possibility of individual intolerance to one of the components of the drug cannot be ruled out. In this case, you should consult your doctor about replacing Terzhinan with any other effective medicine. Terzhinan has no analogues, but in each individual case the doctor will help you choose effective remedy, which will not cause allergies in your particular situation. Allergic reactions in the form of itching, swelling and redness of the genitals are also possible. Such side effects at the first stage of treatment are not indications for discontinuation of the drug. However, you should definitely inform your doctor about them, who will decide on the possibility of further therapy.

Video of using Terzhinan

In the video, the pharmacist talks about the drug Terzhinan, the active ingredients included in its composition, method of use, side effects and contraindications. The video is recommended for viewing by a wide audience

The drug Terzhinan is produced in the form of tablets for vaginal use by a French pharmaceutical company.

Contains several antiseptic (antimicrobial) components. Let's look for Terzhinan candles in detail, as well as instructions for use.

The substance tinidazole has a detrimental effect on anaerobic bacteria, which are the causative agents of trichomoniasis.

Neomycin is an antibacterial substance that affects a number of pathogenic bacteria, causing Various types infections.

Nystatin in the drug has a suppressive effect on fungal infections and suppresses its development. Additionally eliminates the inflammatory process, burning sensation, itching. Has a regenerating effect on the vaginal mucosa.

The drug Terzhinan: indications for use

The main indication for prescribing the drug is infectious and inflammatory processes of the reproductive system caused by pathogenic microorganisms entering the vagina.

The drug Terzhinan is prescribed in the following cases:

• vaginitis (inflammatory process of the vaginal mucosa) caused by putrefactive microflora: staphylococcus, gonococcus;
• nonspecific colpitis;
• vaginal dysbiosis;
• infection caused by the development of Candida (thrush);
• inflammation of the vaginal mucosa of various etiologies.

Terzhinan is also prescribed before the need for surgical intervention in gynecology.

In many cases, the drug is used in labor activity, before artificial interruption pregnancy, if it is necessary to undergo an MRI or fluoroscopy of the pelvic organs. Terzhinan course is recommended before installation intrauterine contraceptives, such as a spiral.

The drug can be used as prophylactic after antibiotic therapy to prevent the development of thrush.

Terzhinan suppositories: use for ureaplasmosis

Ureaplasmosis is an infection caused by small microorganisms, most often transmitted sexually and aggravated by disruption of the immune system. Therefore, it is necessary not only to restore the functioning of the immune system, but also to treat the infection. IN in this case, Terzhinan is not replaceable, since it has a wide spectrum of action against various pathogenic microflora (microorganisms). Additionally, the drug relieves the inflammatory process and restores the structure of the vaginal mucosa.

Great advantage of this product and that it does not violate natural balance and death beneficial microflora, such as after treatment with antibiotics. Therefore, after a course of therapy there is no need to drink lactobacilli to restore the vaginal microflora.

Treatment of thrush with Terzhinan

The drug is successfully used in the treatment of thrush in patients whose pathology is accompanied by a secondary inflammatory process. The product is also excellent for use at the very beginning of the disease to relieve symptoms and suppress the further development of infection.

How to use Terzhinan suppositories

The drug is available in the form of vaginal tablets, shaped like regular suppositories. According to the instructions, the standard course of treatment involves using the drug for at least 10 days, 1-2 tablets per day.

Before administering the tablet, you need to hold it for 20-30 seconds in warm purified water. The tablet is inserted deep into the vagina in the “lying on your back” position. Afterwards you need to lie down in a calm state for 10-15 minutes.

The best time to use the drug is in the evening, since the drug may be released during the day. When using Terzhinan in the morning, you must use sanitary pads.

In the case where there are no obvious pathological processes, but it is only necessary to normalize the imbalance of microflora and relieve minor inflammation, then the course of treatment can be 5-6 days, 1 tablet at night.

When treating a fungal infection such as thrush, the treatment time increases to 20-22 days. After the course, the patient must undergo re-diagnosis, and if necessary, the doctor can prescribe treatment again.

Vaginal tablets Terzhinan during pregnancy and lactation

The official instructions for this drug allow its use during pregnancy, but only under the supervision and recommendations of the attending physician.

The use of this drug is strictly contraindicated for the treatment of patients in the 1st trimester of pregnancy (up to 12 weeks). They begin to use the product from the 2nd and 3rd trimester with the development of inflammatory processes in the vagina of various etiologies.

The drug practically does not enter the blood circulation, therefore the development of signs of overdose or negative influence for the fruit.

Terzhinan suppositories can also be used during breastfeeding; all active components of the product do not pass into breast milk.

Nevertheless, this drug during pregnancy, it is prescribed in the case when the burning, inflammatory process or itching cannot be eliminated by others using medicinal methods failed.

Contraindications to the use of the drug

Terzhinan should not be used if you are intolerant to the main active ingredients. If during treatment you notice allergic manifestations, then the product must be replaced with a more suitable one.

Also, the drug is not prescribed for patients adolescence. In this case, medications in the form of ointments or oral medications should be used.

Possible side effects

The development of side effects is observed in exceptional cases, if you are intolerant to one of the substances of the drug. Terzhinan is well tolerated, absorption into the bloodstream is so insignificant that suppository tablets are safe even during pregnancy.

In rare cases, only local reactions in the form of redness, itching or minor rash at the injection site of Terzhinan.

Use of the drug during the menstrual cycle

Terzhinan suppositories are allowed to be used during menstruation if the patient does not feel discomfort or pain during administration. Therefore, there is no need to discontinue the drug during menstruation.

Drug overdose

No overdose has been observed with the use of this drug.

In some cases, increased side effects may occur in the form of allergic reactions.

No negative manifestations were noted during interactions with other drugs.

The shelf life of Terzhinan is no more than 2 years from the date of manufacture.

Many women know firsthand what it is vaginal infections. You don't have to be promiscuous to get them. Sometimes you can swim in a dirty pond and get a lot of weight unpleasant problems. Modern pharmacology offers many medications to eliminate the infection. Considered to be an effective remedy vaginal tablets Terzhinan. They are available only with a doctor's prescription, so a visit to him is required. Without causing much discomfort to the woman, Terzhinan suppositories treat many infections and are used for their prevention.

Vaginal suppositories Terzhinan

Medication Terzhinan is a multi-component drug for antibacterial therapy, created by French scientists. Indications for use are gynecological infectious diseases, inflammation of the vagina, it is effective for bacterial vaginosis, fungal infections and fungal complications. Terzhinan contains antibacterial components wide range. Suppositories are used for prevention gynecological infections genital organs during appropriate procedures, including abortion.

Some experts recommend using the medication before procedures such as examining the uterus, which involve the use of instruments and devices. The intravaginal method of use turns Terzhinan into a means of precise action. The drug is easy to use, has almost no side effects, and does not come into contact with the mucous membranes of the intestines and stomach.

Compound

Terzhinan contains the following active components:

• ternidazole;
• nystatin;
• prednisolone;
• neomycin sulfate.

The drug contains such auxiliary components as:

• wheat starch;
• colloidal silicon dioxide anhydrous;
• sodium starch glycolate (type a);
• magnesium stearate;
• lactose monohydrate;
• purified water.

Thanks to the combined action of these ingredients, the drug has strong antifungal properties and produces a more complex and extensive antibacterial effect on pathogens without causing harm to the vaginal microflora and female body. All this can be avoided after taking tablets for a course of lactobacilli that restore the microflora. Suppositories have no effect on menstrual cycle.

Release form

Terzhinan is produced only in the form of cream-colored tablets intended for intravaginal use. There is a "T" on each side of the candle. The package contains 6 or 10 pieces. Medicines used directly inside the vagina often come in the form of suppositories, which is why Terzhinan is sometimes called that. The name may also change depending on the number of tablets in the package. Doctors and pharmacists often use the designations "Terzhinan 6" or "Terzhinan 10".

Pharmacodynamics and pharmacokinetics

Ternidazole contained in Terzhinan has a detrimental effect on Trichomonas, kills anaerobic pathogenic bacteria. Neomycin is an aminoglycoside antibiotic. Possessing an antibacterial effect, it prevents pathogenic flora from normally synthesizing proteins, which leads to a slowdown in their reproduction and subsequent death. Aerobic bacteria, such as Staphylococcus aureus methicillin-resistant, listeria and corynebacteria.

Nystatin antifungal belongs to the polyene antibiotic substances. Penetrating into the cell membranes of the “enemy”, it binds with ergosterol, destroying the dangerous microorganism. The antifungal antibiotic is effective against Candida fungi. Capable of affecting only those pathogenic microorganisms that are eukaryotes.

Prednisolone, which is part of the tablets, is a glucocorticosteroid drug that relieves inflammation and is effective in relieving allergic reactions and swelling. Due to the presence of excipients in tablets, epithelial tissue, the vaginal lining receives additional protection and assistance in maintaining pH balance. The pharmacokinetic properties of Terzhinan have not been studied due to its insignificant absorption.

Terzhinan suppositories - indications for use

The indication for use is the prevention of vaginitis before various gynecological procedures, such as installation of an intrauterine device, treatment of cervical erosion, hysterography, hysterosalpingography, abortion. In some cases, gynecologists recommend using a suppository before childbirth or any other actions by doctors that involve the use of instruments in the vagina. The list of infections that Terzhinan can effectively fight:

• Colpitis caused by chlamydia;
• treatment of vaginitis with a mixed causative agent pathogenic microflora(consisting simultaneously of fungi, trichomonas, bacteria and gardnerella);
• vaginitis caused by pathogenic bacteria;
• vaginitis caused by Candida fungi (thrush).

Contraindications

Terzhinan tablets should not be used by pregnant women during the first three months of pregnancy. For more later and for nursing mothers, the drug is prescribed by a specialist in exceptional cases. Its use is prohibited for girls under 16 years of age. The main contraindication is individual hypersensitivity to the ingredients of the drug.

Terzhinan suppositories - instructions for use

No more than one tablet can be placed into the vagina at one time. Exceeding the dosage may cause it to enter the bloodstream. large quantities prednisolone, which can produce side effects typical of glucocorticoid hormone. When treating an infection and using it for prophylactic purposes, one tablet is inserted into the vagina once a day. The duration of the course is determined by the doctor. The tablet must be removed from the blister as quickly as possible so that it does not have time to melt and become soft. The procedure should be carried out with clean hands.

When inserting the suppository, you should be careful not to touch the anus with your fingers, as this may cause infection. The period of menstruation is not a reason to cancel a course of pills. Bleeding will not affect the effect of the drug in any way. You just need to remember that on such days, hygiene requirements increase significantly. If vaginitis is present, antibiotics are sometimes prescribed to the woman's sexual partner. If trichomoniasis has been diagnosed, treatment of the partner will be mandatory. During this period, sexual intercourse should be avoided.

Side effects

In rare cases, problems are noted with eliminating inflammation, which is associated with a reaction to the existing antimicrobial drug corticosteroid. Sometimes the first few days at the beginning of the course, a woman may feel quickly passing discomfort. Possible consequences of using tablets may include local phenomena such as:

• burning;
• tingling;
• swelling and pain syndrome in the vaginal area;
• irritation of the vaginal mucosa.

special instructions

Taking this into account, patients with osteoporosis, heart failure or arterial hypertension Those using Terzhinan should do so under the supervision of doctors and after examination. The attention of specialists during the course of the drug is also required for glaucoma, tuberculosis, myopathy, epilepsy, severe stress or mental disorders, diabetes mellitus and hypothyroidism.

During pregnancy

According to the instructions, the use of suppositories is unacceptable during the first three months of pregnancy. The components of the drug can reach the fetus through the mother's bloodstream. If a pregnant woman has infections, a specialist may prescribe the use of a suppository in the first trimester in exceptional measures. In the second trimester of pregnancy and beyond, the tablets can be used calmly; the drug is no longer able to have an effect on the fetus. Due to the possibility of passage into milk, the suppository is not advisable during lactation.

Drug interactions

Terzhinan's interaction with others medicinal drugs didn't show itself at all.

Overdose

Terzhinan is characterized by insignificant penetration into tissues and circulatory system, which makes the likelihood of an overdose insignificant. If it occurs, the side effects of the drug will become stronger; it can cause burning and discomfort.

Terzhinan is a vaginal tablet that has antifungal, antitrichomoniacal, anti-inflammatory and antibacterial effects. Suitable for complex treatment of infectious gynecological diseases, less often - for prevention. Effective against sexually transmitted diseases, prescribed for candidiasis, trichomoniasis, chlamydia, etc.

Suitable for pregnant and lactating women.

Composition of the drug Terzhinan High efficiency the drug is due to the effect on the fungus of four active ingredients

• , the combination of which ensures rapid recovery:
• nystatin is an antibiotic that acts against fungal infections;
• ternidazole – an antifungal substance;
• prednisolone is a hormone that has anti-inflammatory and antipruritic effects, relieves the symptoms of the disease.

Indications for use

Terzhinan is prescribed not only for thrush (acute and chronic), but also for other gynecological diseases:

• trichomonas vaginitis;
• combined colpitis;
• vaginitis;
• gardnerellosis and chlamydia;
• inflammation of the appendages.

The drug is prescribed for prevention inflammatory diseases in pregnant women, after treatment of cervical erosion, before and after surgical interventions. It is recommended to take Terzhinan before childbirth for women with a predisposition to thrush.

Who are contraindicated for suppositories?

Terzhinan is well tolerated by the body and is suitable for use during pregnancy and lactation. A contraindication is individual intolerance to the components included in the drug. Tablets are not prescribed to young girls under 16 years of age due to the lack of information about the safety of the components on the children's body.

How to take the pills

You need to take Terzhinan for thrush according to the following regimen: 1 tablet every day. The doctor decides how many days the treatment lasts, but for women suffering chronic form candidiasis, you will need to administer suppositories for 10 days.

The tablets are dry, so they need to be slightly moistened before use. warm water, and then insert deep into the vagina and take a horizontal position. Carry out the procedure before going to bed to avoid the candle falling out or leaking out in an already dissolved state.

Side effects in women after using the drug are rare; a burning sensation and irritation of the intimate area may occur.

If long time If your condition does not improve, you will need to adjust your treatment with your doctor. Women experience a decrease in itching and burning after one (maximum three) Terzhinan suppository. And if the tablets do not bring results, you will need to undergo a re-examination or combine the drug with other drugs to treat candidiasis.

Terzhinan for pregnant women

Terzhinan does not cause concern among pregnant women and gynecologists, since its safety for the fetus has been proven by many years of experience in medical use. During the period of waiting for the baby, candles have advantages over competitors:

• even with long-term use substances do not accumulate in the body and are practically not absorbed in the blood, so the drug has no effect on the child;
• high efficiency makes it possible to quickly get rid of the unpleasant symptoms of thrush within a couple of days after starting treatment, which during pregnancy is no less important than proper treatment;
• suppositories have a wide spectrum of action and are effective against many pathogenic microorganisms, which makes it possible to use just one drug to treat several diseases.

Terzhinan is prescribed from the second trimester of pregnancy, but studies conducted in Europe have shown that the drug has no effect on the fetus or on early stages. But precaution in our country comes first, so tablets are not prescribed earlier than 12 weeks and are not allowed for use for a long time. The gynecologist decides how long the course is. For pregnant women, the treatment regimen is adjusted individually after examination..

The drug is not contraindicated during lactation. A young mother may not stop breastfeeding during treatment.

Features of taking Terzhinan

INSTRUCTIONS

1. There is no need to stop treatment with the onset of menstruation. The suppositories take a long time to dissolve without being washed away by menstrual blood.
2. Terzhinan can be taken together with other drugs, including local action. But it’s worth dividing the reception into different time, or use a second medicine after 1-2 hours.
3. At first (2-3 days), Terzhinan relieves symptoms, then begins to fight the infection. Therefore, you cannot discontinue the drug yourself when signs of the disease disappear. If you do not get rid of the fungi, the thrush will worsen again.
4. You cannot use Terzhinan without interruption while self-medicating. This leads to a decrease in immunity and strengthening of infection in the body.
5. Thrush should be treated simultaneously with your sexual partner. During therapy, it is advisable to refrain from sexual contacts, or limit it to a minimum and be sure to use barrier contraception.
6. Suppositories are not canceled if menstruation is delayed, if there is a possibility of pregnancy, or if successful conception is confirmed. It is important to finish treating thrush because it affects the fetus more than pills.
7. The tablets dissolve in the vagina, but are not absorbed into its mucous membranes. The next day after evening administration, yellowish liquid discharge, which is normal during treatment.

The safety of the drug for women, pregnant and lactating, should not encourage self-medication and uncontrolled use of pills for a long time. After completing the course, smears are examined to determine the state of the microflora. Based on the test results, the doctor decides whether to prescribe further therapy.

Combined drug for local use in gynecology. It has antimicrobial, anti-inflammatory, antiprotozoal, antifungal effect; ensures the integrity of the vaginal mucosa and constant pH.

Ternidazole - antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (a component of the cell membrane), changes the structure and properties of the cell membrane. It has a trichomonacid effect and is also active against anaerobic bacteria, in particular Gardnerella spp.

Neomycin is a broad-spectrum antibiotic from the aminoglycoside group. Acts bactericidal against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative ( Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; inactive against Streptococcus spp. Microbial resistance develops slowly and to a small extent.

Nystatin is an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi genus Candida, changes permeability cell membranes and slows down their growth.

Prednisolone is a dehydrated analogue of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.

Pharmacokinetics

Release form

Vaginal tablets are light yellow in color, with possible inclusions of darker or lighter shades, flat, oblong in shape, with chamfered edges and printed in the form of the letter “T” on both sides.

Excipients: wheat starch - 264 mg, lactose monohydrate - q.s. up to 1.2 g, colloidal silicon dioxide - 6 mg, magnesium stearate - 10 mg, sodium carboxymethyl starch - 48 mg.

Dosage

For vaginal administration.

1 tablet is inserted deep into the vagina while lying down before bed. Before administration, the tablet should be kept in water for 20-30 seconds. After administration, you must lie down for 10-15 minutes.

Average duration treatment course- 10 days; in case of confirmed mycosis, the duration of treatment can be increased to 20 days; The average duration of a preventive course is 6 days.

Overdose

There are no data on cases of overdose.

Interaction

Drug interactions The drug Terzhinan was not identified.

Side effects

Local reactions: rarely - burning sensation, itching and irritation in the vagina (especially at the beginning of therapy).

Other: in some cases - allergic reactions.

Indications

• bacterial vaginitis;
• vaginal trichomoniasis;
• vaginitis caused by fungi of the genus Candida;

The use of Terzhinan in the first trimester of pregnancy and during lactation (breastfeeding) is possible only in cases where the expected benefit of therapy for the mother outweighs the potential risk for the fetus or infant.

special instructions

In the case of treatment of vaginitis and trichomoniasis, simultaneous treatment of sexual partners is recommended.

Treatment should not be stopped during menstruation.

For treatment and prevention, one tablet must be administered once a day for the period of time prescribed by the doctor.

The tablet should be removed from the packaging immediately before use and inserted into the vagina as quickly as possible, otherwise it may begin to soften and melt. A soft tablet is much more difficult to insert into the vagina correctly. To remove Terzhinan from the package, the foil must be torn along the length of the tablet or cut with scissors.

Terzhinan should always be administered with freshly washed hands with soap or wearing sterile surgical gloves. No manipulation allowed with dirty hands. Moreover, hands that have not been washed for an hour are considered dirty, even if the woman was at home or in a relatively clean room.

Before administering the Terzhinan tablet, it is recommended to wash your hands with soap - solid or liquid, and not to use various commercially available lotions, waters, foaming compounds, emulsions and other products designed to remove contaminants from the skin of the hands. The only product that can be used to wash and treat your hands before inserting the tablets into the vagina is antiseptic or antibacterial liquids.

In addition, you should avoid touching the anus with your fingers while inserting the tablet into the vagina, as this may lead to additional infection.

If part of the course of treatment with Terzhinan tablets falls on the period menstrual bleeding, then it should not be interrupted. In other words, the tablets must continue to be inserted into the vagina during menstrual bleeding, since their effectiveness does not decrease. But during menstruation, you should especially carefully observe the rules of hygiene when administering tablets.

If a woman has been diagnosed with vaginitis, it is recommended to undergo a course of therapy not only for her, but also for her sexual partner. This recommendation should be considered mandatory in the case of trichomoniasis. In other situations, treatment of the sexual partner is advisory.

During the entire period of therapy, it is necessary to refrain from sexual intercourse and not to use lubricants, gels, ointments or any other means intended for insertion into the vagina, as they can completely neutralize the therapeutic effect of Terzhinan.

How to properly administer Terzhinan vaginally?

It is optimal to administer the drug in the evening hours just before going to bed, but if for some reason this is not possible, then Terzhinan can be used at any time of the day. The main thing is to follow the rule - administer one suppository per day.

Firstly, before inserting the tablet, you should wash the external genitalia and the perineal area, including anal hole, warm water and soap. It is not recommended to use any gels or other hygiene products for washing. Then you need to wash your hands with soap or treat them antiseptic liquid. If it is impossible to wash your hands for any reason, you should put on sterile surgical gloves, which are sold in pharmacies.

After this, remove the tablet from the package and place it in a cup with clean, cool water. boiled water for 20 - 30 seconds to upper layer dissolved a little, and the drug began to act immediately.

The tablet is removed from the cup and taken into a position convenient for administration. We should dwell on this point in more detail, since the instructions for use indicate that the tablet should be administered in a lying position. However, it is not convenient for all women to administer the drug while lying on their back, since the tablet is quite small and difficult to push into a collapsed vagina. Therefore, doctors recommend administering the drug in the position in which it is most convenient to do this, but in close proximity to the bed or sofa, on which you will need to lie down for a while after performing the manipulation.

The most convenient positions for administering Terzhinan tablets are:
1. Squatting with your knees wide apart.
2. Standing, with one leg raised and resting on a chair or other elevation.
3. Lying on your back with your knees and hips bent and your legs pulled to your stomach.

By selecting optimal posture, it is necessary to carefully spread the labia to the sides with the fingers of your non-working hand (left for right-handers and right for left-handers) and expose the entrance to the vagina. Then index finger Using your working hand, push the tablet forward deeply until it stops moving.

After this, the finger must be removed from the vagina and, making a minimum of movements, lie on your back on a bed or sofa. You should lie in this position for 10–20 minutes so that the tablet is completely dissolved and active substances began to be absorbed into the cells of the vaginal mucosa.

After 10 - 20 minutes, you can get up, put on your panties, putting a panty liner on them, since discharge may appear, and go about your business.

How long does the treatment last?

For treatment and prevention, it is necessary to administer one tablet of Terzhinan every day during the entire course of therapy. Treatment of various vaginitis usually lasts 10 days, but with confirmed candidiasis, the course of therapy is extended to 20 days. Preventive use of Terzhinan tablets is carried out for 6 days.

Application of Terzhinan during the day

The use of Terzhinan during the day is quite possible if the woman has the conditions for proper insertion of the tablets into the vagina. The instructions for use of the drug indicate that it is recommended to use the tablets in the evening, before going to bed. This recommendation is due to the fact that such tactics will ensure a long-term, for several hours, presence of the active components in the vagina, from where they will flow out in minimal quantities due to horizontal position bodies. However this recommendation is not strict and can be completely ignored.

That is, Terzhinan tablets can be inserted into the vagina during the day, in the morning, in the early evening, etc. But in this case, after performing the manipulation, you should definitely lie down for 10–20 minutes on your back on a flat surface, and only then get up or sit down. Also, when administering Terzhinan tablets during the daytime, you should use panty liners, since a small portion of the melted medicine will flow out under the influence of gravity. In addition, it is morally and psychologically necessary to adjust to the fact that with daily administration of Terzhinan tablets, it is necessary to increase the duration of therapy by approximately 1/4 - 1/3 in order to compensate for the leaked volume of the drug. That is, if a 10-day course of Terzhinan is prescribed, then when introducing tablets during the day, it should be increased to 12 - 13 days, etc.

After Terzhinan

If the tablets were inserted into the vagina in the evening, before going to bed, then in the morning the woman may have yellow, profuse mucous discharge, sometimes lemon-colored, for 1 to 3 hours. This is normal and represents the release of excess and remnants of the tablet from the vagina. The discharge will stop as soon as the woman completes the course of therapy or prevention with Terzhinan tablets. If the tablets are used during the day, such discharge may appear approximately an hour after administration and continue for another 2 to 4 hours.

In some women Terzhinan causes severe itching, which they mistake for a relapse of thrush. However, this drug is not capable of causing thrush, since it contains components that have a detrimental effect on fungi of the genus Candida, which are the causative agents of the disease. Therefore, other factors are the cause of itching and discharge during the use of Terzhinan.

So, normally, in the first days of treatment, the tablets can actually cause itching, which gradually decreases and completely disappears by the end of therapy. If the itching does not decrease or disappear, then most likely this is a manifestation of an allergic reaction that requires discontinuation of Terzhinan.

After using Terzhinan, many doctors recommend starting a course of any suppositories containing lactobacilli and bifidobacteria for speedy recovery microflora. The suppositories most often used for this purpose are Vagisan, Acylact, Bifidumbacterin and others. Separately, it should be noted the drug Vagilak, which is capsules for oral administration containing strains of lactobacilli that penetrate well from the intestines into the vagina and take root well in it. Also, to restore the vaginal microflora after treatment with Terzhinan, you can take regular probiotics, since normalization intestinal microflora will speed up this process in the genitals.

Impact on the ability to operate machinery

Terzhinan tablets do not affect the ability to operate machinery, so women using the drug can engage in any type of activity that requires high speed reactions and concentration.

Overdose

An overdose of Terzhinan is impossible due to the insignificant absorption of the active components into the systemic circulation.

Interaction with other drugs

Terzhinan tablets do not significantly interact with any other medications, so they can be used in combination with any medications.

Treatment with Terzhinan - effective regimens

Many women are not completely satisfied with the result of treatment with Terzhinan, since they may still have some discomfort or unpleasant sensations after completion of therapy or may arise directly during the use of the tablets. To relieve these unpleasant sensations, among which the most common are itching, burning, discharge, pain at the end of urination and pain during sexual intercourse, Terzhinan is used in combination with other medications.

Thus, in order to relieve itching and prevent triangular discharge similar to thrush that occurs in the first days of using Terzhinan, it is recommended to use Pimafucin suppositories for 3 to 5 days beforehand. This tactic makes the use of Terzhinan comfortable and almost invisible.

For cupping discomfort that arise after treatment with Terzhinan, which in most cases are caused by the absence of normal vaginal microflora, since the pathological one was destroyed during therapy, and the normal one has not yet had time to populate, microsyringes with the antiseptic Tantum Rose or probiotic preparations are used. Among the probiotics, the most effective are Vagisan, Vagilak, Acipol and others.

Separately, it is worth noting Vagilak, which is a capsule for oral administration, which is very convenient because you do not need to insert anything into the vagina again. These capsules contain lactobacilli that are able to penetrate the vaginal wall through the intestinal wall, quickly colonize it and take root, thanks to which Vagilak quickly restores normal microflora.

Use for thrush

For thrush, Terzhinan is an effective treatment, since it contains two active components that have a detrimental effect on different types fungi. However, to achieve stable remission and stop relapses of thrush for a long period of time, Terzhinan tablets for thrush should be used for 20 days. If not only fungi of the genus Candida, but also mycelium are found in a vaginal smear, then for effective treatment it should be taken in combination with Terzhinan tablets antifungal drugs containing fluconazole (Diflucan, Diflazol, etc.), orally. Moreover, antifungal drugs should be taken during the entire course of therapy with Terzhinan, that is, for 20 days. The drug regimen can be twofold:
1. Take any fluconazole drug 50 mg once a day daily.
2. Take any fluconazole drug 150 mg 1 time per day every three days.

If the specified treatment regimen is followed, thrush is completely cured and its relapses do not bother the woman for several years.

Terzhinan during pregnancy and breastfeeding

During the entire first trimester of pregnancy (from the beginning to the 12th week of gestation inclusive), Terzhinan tablets cannot be used, since the active components can penetrate the uterus and have a negative effect on the fetus. However, if the woman’s condition is not satisfactory, which can also negatively affect the course of pregnancy, then Terzhinan tablets are also used in the first trimester.

From the second trimester of pregnancy until childbirth, Terzhinan can be used without fear, since during these periods of gestation the drug is no longer able to have a negative effect on the fetus.

Side effects

Terzhinan can cause the following symptoms as side effects:

• Feeling of itching, burning and irritation in the vagina;
• Allergic reactions (rash, hives, itchy skin, etc.).

Itching, burning and irritation in the vagina usually occur at the beginning of therapy, and completely disappear by the time it is completed.

Contraindications for use

Terzhinan tablets are contraindicated for use only if a woman has an individual hypersensitivity to the components of the drug.

Terzhinan tablets (suppositories): release form, composition, indications, instructions for use, dosages, contraindications, side effects - video

Analogs

There are no synonyms for Terzhinan tablets, since in the domestic language pharmaceutical market There are no drugs that have an identical composition of active ingredients. However, there is a fairly wide range of analogues that contain other active components, but have exactly the same therapeutic effect.

The following drugs are analogues of Terzhinan:

• Vagisept vaginal suppositories;
• Vagiferon vaginal suppositories;
• Gainomax vaginal suppositories;
• Ginalgin vaginal tablets;
• Giterna vaginal tablets;
• Klion-D 100 vaginal tablets;
• Clomegel vaginal gel;
• Metrogyl Plus vaginal gel;
• Metromicon-Neo vaginal suppositories;
• Neo-Penotran, Neo-Penotran forte and Neo-Penotran forte L vaginal suppositories;
• Polygynax vaginal capsules;
• Polygynax Virgo emulsion for insertion into the vagina;
• Elzhina vaginal tablets.

Cheaper analogues of Terzhinan

The cheapest analogues of Terzhinan are the following drugs:

• Vagisept – 209 – 230 rubles;
• Ginalgin – 230 – 300 rubles;
• Clomegel – 60 – 120 rubles;
• Metromicon-Neo – 300 – 400 rubles for 14 tablets.

What is better than Terzhinan?

It is almost impossible to answer the question of which is better than Terzhinan, since medical practice There is no concept of best, but there is a definition of optimal. Thus, the optimal drug is considered to be the one that is most effective for a given woman at a given time. This means that for the same disease in different periods Over time, completely different drugs can be effective, each of which will be optimal, but at different moments.

Terzhinan is an effective drug that is well suited for many women, so it is considered a “good” remedy. If the drug is not suitable for any woman at a given moment, then she will have to try using analogues. And the analogue that turns out to be the most suitable and effective will be the best for this woman at the current moment in time.

According to reviews from doctors and women, good analogues Terzhinana are Vagisept, Polygynax, Gaynomax and Elzhina. Therefore, if Terzhinan for some reason did not suit a woman or was not effective enough, then it is recommended to try these drugs, which are highly likely to be better.

Reviews about the drug

More than 80% of reviews about Terzhinan tablets are positive, which is due to their high effectiveness in the treatment of colpitis, vulvovaginitis, thrush and bacterial vaginosis. Women in the reviews note that the pills quickly stop unpleasant symptoms and cure the disease, which is confirmed not only by a subjective improvement in well-being, but also by the results of a smear.

Women also used Terzhinan before treating cervical erosion (“cauterization”) in order to eliminate the inflammatory process in the vagina and normalize the smear. In almost all cases, the drug was effective.

Negative reviews are usually associated with a burning sensation, irritation and itching that occurs at the beginning of therapy and goes away after 2 to 4 days. However, some women find it very difficult to tolerate these symptoms, as a result of which they stop using Terzhinan and leave a negative review of the drug.

A combined local drug used in the field of gynecology is Terzhinan. Instructions for use recommend using the product for bacterial vaginitis, vaginal trichomoniasis, as well as fungal and mixed vaginitis. This medication has antibacterial, antiprotozoal, antifungal and anti-inflammatory effects.

Composition and release form

The product is produced in the form vaginal suppositories(tablets). In addition to the active ingredients, the Terzhinan vaginal tablet includes: wheat starch (Amylum tritici), colloidal silicon dioxide (Silicii dioxydum colloidale), sodium starch (type A; Natrii amylum), magnesium stearate (Magnesium stearate), lactose (Lactose).

Pharmacological properties

The active components of Terzhinan have antibacterial, antiprotozoal, anti-inflammatory and antifungal effects due to its constituent components:

• Ternidazole, which is active against many anaerobic bacteria (in particular Gardnerella spp.), has a pronounced trichomonacid effect.
• Nystatin is a highly active antifungal antibiotic (against fungi of the genus Candida).
• Neomycin sulfate belongs to the group of broad-spectrum antibiotics (aminoglycoside group).
• Prednisolone has an anti-inflammatory effect.

This composition of the drug Terzhinan, the instructions for use indicate this, ensures the integrity of the vaginal mucosa and a stable pH value.

Medicine Terzhinan: what helps

The main indications for the use of Terzhinan are vaginitis, which is caused by microorganisms sensitive to the action of the drug. Use the drug in the following situations:

• Bacterial vaginosis.
• Bacterial vaginitis.
• Vaginitis, which is caused by fungi of the genus Candida.
• Trichomoniasis of the vagina.
• Mixed vaginitis.

In addition, Terzhinan (according to medical specialists) is very effective for the prevention of vaginitis in the following cases:

• Before performing hysterography.
• Before and after installation of the IUD and diathermocoagulation of the cervix.
• Before performing various gynecological operations.
• Before childbirth and abortion.

Terzhinan for thrush

Terzhinan is recommended for the treatment of women whose thrush is accompanied by suspected secondary inflammation or infection with secondary microflora. In addition, the use of Terzhinan is resorted to in cases where the symptoms are so pronounced that they should be stopped as quickly as possible.

In some cases, the drug is indicated as a substitute complex therapy, if previous treatment with other antifungal agents was ineffective. Reviews of suppositories for thrush left by patients and practicing gynecologists suggest that Terzhinan successfully cures fungal infection without causing the development of unwanted side reactions.

The use of Terzhinan suppositories for ureaplasmosis

Despite the fact that the active growth of ureaplasmosis is most often associated with malfunctions of the immune system, treatment with the use of immunomodulatory medicines does not always allow you to achieve the desired result. In this situation, they resort to prescribing special antibacterial agents or antibiotics.

Very often, for ureaplasma, doctors recommend Terzhinan, which acts on a wide range of pathogenic microorganisms and provides a pronounced anti-inflammatory effect. Valuable property The drug is that, while provoking the death of microbes and fungi, it does not disturb the natural microflora of the vagina.

Contraindications

Terzhinan instructions for use prohibit the use only in case of individual intolerance to the drug. This is fraught with allergic reactions. In other cases there are no contraindications.

Medicine Terzhinan: instructions for use

According to indications, Terzhinan is prescribed in the amount of one vaginal tablet per day, usually before bedtime. Before insertion into the vagina, the tablet must be kept in water for 20-30 seconds. The average duration of use of the drug is ten days, but the course of therapy with Terzhinan can be extended to 20 days if indicated.

You should not stop treatment with the drug during menstruation. An overdose of the drug is unlikely, since Terzhinan, according to the instructions, does not have high degree absorption into the bloodstream. According to indications, the product can be used during pregnancy and lactation.

Side effects

Terzhinan, instructions and reviews explain, quite rarely provokes side effects. Since suppositories are used topically, their constituent components are absorbed into the systemic circulation in very small concentrations. Therefore, in most recorded cases they provoked exclusively local reactions, which were expressed as:

• allergy symptoms;
• burning sensations;
• tingling;
• itching;
• soreness;
• irritation at the injection site.

Systemic effects during treatment with the drug occur in isolated cases. Possible reaction the use of glucocorticosteroids (and, in particular, prednisone) is a slowdown in the healing processes of wounds and cracks, and atrophic processes in the mucous membrane may also occur in some patients.

Analogs

Many patients, having received a prescription for the drug from a doctor, try to find a cheaper alternative to Terzhinan. Currently, the medicine has no analogues. For women who have been diagnosed bacterial vaginosis or vaginitis, may be prescribed whole line drugs, for example: Neotrisol, Polygynax or Meratin Combi. Despite the fact that they are similar in action to Terzhinan, the latter is unique in its composition and ability to have a complex effect on inflammatory and infectious processes affecting the mucous membrane of the female external genital organs.

Price

The average price of Terzhinan candles in Ukraine is 156-170 UAH. How much do candles cost in Russia? The price of 10 Terzhinan tablets varies - from 366 to 410 rubles. You can buy candles in Belarus for 17.5 - 23 Belarusian rubles.

A drug with antibacterial, antiprotozoal, antifungal and anti-inflammatory effects for local application in gynecology

Release form, composition and packaging

Vaginal tablets light yellow in color, with possible inclusions of darker or lighter shades, flat, oblong in shape, chamfered along the edges and printed in the form of the letter "T" on both sides.

Excipients: wheat starch - 264 mg, lactose monohydrate - q.s. up to 1.2 g, colloidal silicon dioxide - 6 mg, magnesium stearate - 10 mg, sodium carboxymethyl starch - 48 mg.

6 pcs. - strips (1) - cardboard packs.
10 pieces. - strips (1) - cardboard packs.

pharmachologic effect

Combined drug for local use in gynecology. Has antimicrobial, anti-inflammatory, antiprotozoal, antifungal effects; ensures the integrity of the vaginal mucosa and constant pH.

Ternidazole- an antifungal agent from the group of imidazole derivatives, reduces the synthesis of ergosterol (a component of the cell membrane), changes the structure and properties of the cell membrane. It has a trichomonacid effect and is also active against anaerobic bacteria, in particular Gardnerella spp.

Neomycin- a broad-spectrum antibiotic from the group of aminoglycosides. It has a bactericidal effect against gram-positive (Staphylococcus, Streptococcus pneumoniae) and gram-negative (Escherichia coli, Shigella dysenteriae, Shigella flexneri, Shigella boydii, Shigella sonnei, Proteus spp.) microorganisms; inactive against Streptococcus spp. Microbial resistance develops slowly and to a small extent.

Nystatin- an antifungal antibiotic from the group of polyenes, highly effective against yeast-like fungi of the genus Candida, changes the permeability of cell membranes and slows down their growth.

Prednisolone- dehydrogenated analogue of hydrocortisone, has a pronounced anti-inflammatory, anti-allergic, anti-exudative effect.

Pharmacokinetics

Data on the pharmacokinetics of the drug Terzhinan are not provided.

Indications

Treatment of vaginitis caused by microorganisms sensitive to the drug, including:

Bacterial vaginitis;

Vaginal trichomoniasis;

Vaginitis caused by fungi of the genus Candida;

Mixed vaginitis.

Prevention of urogenital infections/vaginitis, incl..

Terginan vaginal tablets are a topical drug that is generally well tolerated. But this is if the treatment is carried out according to all the rules: as prescribed by the doctor and under laboratory control. Otherwise (and many women use it for self-medication), side effects cannot be avoided.

Terzhinan vaginal tablets are a highly effective combined medicinal product complex antibacterial, antifungal, antitrichomoniacal and anti-inflammatory action. Terzhinan vaginal tablets contain essential and Excipients, which interact to create a complex effect of getting rid of infection, inflammation and preventing injury to the vaginal mucosa. The composition of terzhinan includes antibacterial agent neomycin (broad-spectrum antibiotic), antifungal agent nystatin (an antifungal antibiotic), the antiprotozoal drug ternidazole, and the anti-inflammatory drug prednisolone (a glucocorticoid hormone).

Manufacturer version

A conscientious manufacturer (“Bouchard-Recordati laboratory, France”) after numerous laboratory and clinical trials(including on pregnant women suffering from vaginitis of various origins) found that with proper use of the drug, side effects can only be in the form of allergic reactions (in this case the drug is discontinued) and in the form of local irritation of the mucous membranes, which are manifested by some increased burning and itching and disappear after a while, so they do not require discontinuation of the drug.

Self-medication

Prednisolone is generally very dangerous drug, in this case, when taking terzhinan vaginal tablets, it is assumed that the body is protected from its side effects various drugs that kill the infection. But as soon as the drug is no longer used, the decrease in immunity makes itself felt. Therefore, competent gynecologists always prescribe Terzhinan after treatment with vaginal tablets rehabilitation treatment in the form of drugs that help restore normal vaginal microflora. It is the normal microflora of the vagina that can restore local immunity. The bacteria that it contains secrete lactic acid, which makes the environment in the vagina acidic and uncomfortable for opportunistic microflora. This helps restore immunity over time.

If a gynecologist prescribes Terzhinan vaginal tablets, then this automatically means it correct application with laboratory control. Treatment with terzhinan blindly, independently, is absolutely contraindicated.

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